The Drug Ontology

Last uploaded: February 15, 2019
Preferred Name

famciclovir

Synonyms

FCV

InChIKey=GGXKWVWZWMLJEH-UHFFFAOYSA-N

C14H19N5O4

BRL-42810

famciclovir

famciclovirum

FAMCICLOVIR

2-(2-(2-amino-9H-purin-9-yl)ethyl)-1,3-propanediol diacetate

2-[(acetyloxy)methyl]-4-(2-amino-9H-purin-9-yl)butyl acetate

InChI=1S/C14H19N5O4/c1-9(20)22-6-11(7-23-10(2)21)3-4-19-8-17-12-5-16-14(15)18-13(12)19/h5,8,11H,3-4,6-7H2,1-2H3,(H2,15,16,18)

CC(=O)OCC(CCn1cnc2cnc(N)nc12)COC(C)=O

9-[4-acetoxy-3-(acetoxymethyl)but-1-yl]-2-aminopurine

acetic acid 2-acetoxymethyl-4-(2-amino-purin-9-yl)-butyl ester

Definitions

2-Amino-9H-purine in which the hydrogen at position 9 is substituted by a 4-acetoxy-3-(acetoxymethyl)but-1-yl group. A prodrug of the antiviral penciclovir, it is used for the treatment of acute herpes zoster (shingles), for the treatment or suppression of recurrent genital herpes in immunocompetent patients and for the treatment of recurrent mucocutaneous herpes simplex infections in HIV infected patients.

ID

http://purl.obolibrary.org/obo/CHEBI_4974

database_cross_reference

KEGG DRUG:D00317

Wikipedia:Famciclovir

KEGG DRUG:104227-87-4

ChEMBL:17870541

ChemIDplus:104227-87-4

ChEMBL:9719596

DrugBank:DB00426

Patent:US5246937

ChEMBL:2754699

Reaxys:4208403

ChEMBL:174284

has_alternative_id

CHEBI:174284

has_exact_synonym

FAMCICLOVIR

2-[(acetyloxy)methyl]-4-(2-amino-9H-purin-9-yl)butyl acetate

has_related_synonym

FCV

InChIKey=GGXKWVWZWMLJEH-UHFFFAOYSA-N

C14H19N5O4

BRL-42810

famciclovir

famciclovirum

2-(2-(2-amino-9H-purin-9-yl)ethyl)-1,3-propanediol diacetate

InChI=1S/C14H19N5O4/c1-9(20)22-6-11(7-23-10(2)21)3-4-19-8-17-12-5-16-14(15)18-13(12)19/h5,8,11H,3-4,6-7H2,1-2H3,(H2,15,16,18)

CC(=O)OCC(CCn1cnc2cnc(N)nc12)COC(C)=O

9-[4-acetoxy-3-(acetoxymethyl)but-1-yl]-2-aminopurine

acetic acid 2-acetoxymethyl-4-(2-amino-purin-9-yl)-butyl ester

has_RxCUI

68099

id

CHEBI:4974

label

famciclovir

notation

CHEBI:4974

prefixIRI

CHEBI:4974

prefLabel

famciclovir

textual definition

2-Amino-9H-purine in which the hydrogen at position 9 is substituted by a 4-acetoxy-3-(acetoxymethyl)but-1-yl group. A prodrug of the antiviral penciclovir, it is used for the treatment of acute herpes zoster (shingles), for the treatment or suppression of recurrent genital herpes in immunocompetent patients and for the treatment of recurrent mucocutaneous herpes simplex infections in HIV infected patients.

subClassOf

http://purl.obolibrary.org/obo/CHEBI_47622

http://purl.obolibrary.org/obo/CHEBI_20702

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http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29044 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29044 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29044 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29044 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29044 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29044 NCIT LOOM
http://purl.jp/bio/4/id/200906085346025605 IOBC LOOM
http://purl.jp/bio/4/id/200906085346025605 IOBC LOOM
http://purl.jp/bio/4/id/200906085346025605 IOBC LOOM
http://purl.jp/bio/4/id/200906085346025605 IOBC LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000148380 NDFRT LOOM
http://purl.bioontology.org/ontology/SNMI/C-55B14 SNMI LOOM
http://purl.bioontology.org/ontology/MESH/D000077595 MESH LOOM
http://purl.bioontology.org/ontology/RXNORM/68099 RXNORM LOOM
http://purl.bioontology.org/ontology/UATC/S01AD07 ATC LOOM
http://purl.obolibrary.org/obo/CHEBI_4974 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_4974 BIOMODELS SAME_URI
http://purl.obolibrary.org/obo/CHEBI_4974 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_4974 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_4974 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_4974 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_4974 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_4974 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_4974 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_4974 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_4974 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_4974 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_4974 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_4974 DINTO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_4974 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_4974 CHEBI SAME_URI
http://purl.bioontology.org/ontology/LNC/LP157326-2 LOINC LOOM
http://www.co-ode.org/ontologies/galen#Famciclovir GALEN LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C060590 RH-MESH LOOM
http://purl.bioontology.org/ontology/VANDF/4020882 VANDF LOOM
http://purl.bioontology.org/ontology/UATC/J05AB09 ATC LOOM
http://purl.bioontology.org/ontology/LNC/MTHU045606 LOINC LOOM
http://stirdf.jst.go.jp/id/200907093494886110 IOBC LOOM
http://stirdf.jst.go.jp/id/200907093494886110 IOBC LOOM
http://stirdf.jst.go.jp/id/200907093494886110 IOBC LOOM
http://stirdf.jst.go.jp/id/200907093494886110 IOBC LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387557001 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/NDDF/004470 NDDF LOOM