loading...| Preferred Name |
meropenem |
|
| Synonyms |
(6S)-2-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-6-[(1R)-1-hydroxyethyl]-1beta-methyl-2,3-didehydro-1-carbapenam-3-carboxylic acid Meropenem meropenem anhydrous Antibiotic SM 7338 (4R,5S,6S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]thio}-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid (1R,5S,6S)-2-[(3S,5S)-5-DIMETHYLAMINOCARBONYLPYRROLIDIN-3-YLTHIO]-6-[(R)-1-HYDROXYETHYL]-1-METHYLCARBAPEN-2-EM-3-CARBOXYLIC ACID meropenemum MEPM meropenem |
|
| Definitions |
A carbapenemcarboxylic acid in which the azetidine and pyrroline rings carry 1-hydroxymethyl and in which the azetidine and pyrroline rings carry 1-hydroxymethyl and 5-(dimethylcarbamoyl)pyrrolidin-3-ylthio substituents respectively. |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_43968 |
|
| charge |
0 |
|
| database_cross_reference |
PMID:10776838 Patent:US4943569 Beilstein:6826115 Wikipedia:Meropenem Patent:EP126587 PMID:7588092 PMID:28371721 CAS:96036-03-2 PMID:18645546 PMID:28343819 DrugBank:DB00760 Drug_Central:1709 PMID:18611786 LINCS:LSM-5208 PMID:28669829 PMID:11069213 PMID:28677407 PDBeChem:MER PMID:28583381 |
|
| definition |
A carbapenemcarboxylic acid in which the azetidine and pyrroline rings carry 1-hydroxymethyl and in which the azetidine and pyrroline rings carry 1-hydroxymethyl and 5-(dimethylcarbamoyl)pyrrolidin-3-ylthio substituents respectively. |
|
| formula |
C17H25N3O5S |
|
| has role | ||
| has_exact_synonym |
(6S)-2-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-6-[(1R)-1-hydroxyethyl]-1beta-methyl-2,3-didehydro-1-carbapenam-3-carboxylic acid Meropenem |
|
| has_obo_namespace |
chebi_ontology |
|
| has_related_synonym |
meropenem anhydrous Antibiotic SM 7338 (4R,5S,6S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]thio}-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid (1R,5S,6S)-2-[(3S,5S)-5-DIMETHYLAMINOCARBONYLPYRROLIDIN-3-YLTHIO]-6-[(R)-1-HYDROXYETHYL]-1-METHYLCARBAPEN-2-EM-3-CARBOXYLIC ACID meropenemum MEPM meropenem |
|
| has_RxCUI |
29561 |
|
| id |
CHEBI:43968 |
|
| in_subset | ||
| inchi |
InChI=1S/C17H25N3O5S/c1-7-12-11(8(2)21)16(23)20(12)13(17(24)25)14(7)26-9-5-10(18-6-9)15(22)19(3)4/h7-12,18,21H,5-6H2,1-4H3,(H,24,25)/t7-,8-,9+,10+,11-,12-/m1/s1 |
|
| inchikey |
DMJNNHOOLUXYBV-PQTSNVLCSA-N |
|
| label |
meropenem |
|
| mass |
383.46300 |
|
| monoisotopicmass |
383.15149 |
|
| notation |
CHEBI:43968 |
|
| prefLabel |
meropenem |
|
| smiles |
[H][C@]12[C@@H](C)C(S[C@@H]3CN[C@@H](C3)C(=O)N(C)C)=C(N1C(=O)[C@]2([H])[C@@H](C)O)C(O)=O |
|
| subClassOf |
http://purl.obolibrary.org/obo/CHEBI_46770 http://purl.obolibrary.org/obo/CHEBI_79020 |