The Drug Ontology

Last uploaded: March 3, 2024
Preferred Name

Benztropine

Synonyms

Benzatropine

(3-endo)-3-(diphenylmethoxy)-8-methyl-8-azabicyclo[3.2.1]octane

benzatropina

benzatropine

benzhydryl 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ether

benzatropinum

tropine benzohydryl ether

3alpha-benzhydryloxy-8-methyl-8-azabicyclo[3.2.1]octane

3alpha-(diphenylmethoxy)tropane

Benztropine

3alpha-(diphenylmethoxy)-1alphaH,5alphaH-tropane

3endo-benzhydryloxytropane

Definitions

Tropane in which a hydrogen at position 3 is substituted by a diphenylmethoxy group (endo-isomer). An acetylcholine receptor antagonist, it is used (particularly as its methanesulphonate salt) in the treatment of Parkinson's disease, and to reduce parkinsonism and akathisia side effects of antipsychotic treatments.

ID

http://purl.obolibrary.org/obo/CHEBI_3048

charge

0

database_cross_reference

Patent:US2595405

Beilstein:90688

Drug_Central:333

Wikipedia:Benzatropine

CAS:86-13-5

DrugBank:DB00245

KEGG:D07511

KEGG:C06846

definition

Tropane in which a hydrogen at position 3 is substituted by a diphenylmethoxy group (endo-isomer). An acetylcholine receptor antagonist, it is used (particularly as its methanesulphonate salt) in the treatment of Parkinson's disease, and to reduce parkinsonism and akathisia side effects of antipsychotic treatments.

formula

C21H25NO

has role

http://purl.obolibrary.org/obo/CHEBI_48876

http://purl.obolibrary.org/obo/CHEBI_50370

http://purl.obolibrary.org/obo/CHEBI_146270

http://purl.obolibrary.org/obo/CHEBI_48407

has_alternative_id

CHEBI:661238

has_exact_synonym

Benzatropine

(3-endo)-3-(diphenylmethoxy)-8-methyl-8-azabicyclo[3.2.1]octane

has_obo_namespace

chebi_ontology

has_related_synonym

benzatropina

benzatropine

benzhydryl 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ether

benzatropinum

tropine benzohydryl ether

3alpha-benzhydryloxy-8-methyl-8-azabicyclo[3.2.1]octane

3alpha-(diphenylmethoxy)tropane

Benztropine

3alpha-(diphenylmethoxy)-1alphaH,5alphaH-tropane

3endo-benzhydryloxytropane

has_RxCUI

1424

id

CHEBI:3048

in_subset

http://purl.obolibrary.org/obo/chebi#3_STAR

inchi

InChI=1S/C21H25NO/c1-22-18-12-13-19(22)15-20(14-18)23-21(16-8-4-2-5-9-16)17-10-6-3-7-11-17/h2-11,18-21H,12-15H2,1H3/t18-,19+,20+

inchikey

GIJXKZJWITVLHI-PMOLBWCYSA-N

label

benzatropine

Benztropine

mass

307.42930

monoisotopicmass

307.19361

notation

CHEBI:3048

prefLabel

Benztropine

smiles

[H][C@]1(C[C@]2([H])CC[C@]([H])(C1)N2C)OC(c1ccccc1)c1ccccc1

subClassOf

http://purl.obolibrary.org/obo/CHEBI_50996

Delete Subject Author Type Created
No notes to display
Create mapping

Delete Mapping To Ontology Source
http://purl.obolibrary.org/obo/CHEBI_3048 PDRO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_3048 FIDEO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_3048 INBANCIDO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_3048 DINTO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_3048 BERO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_3048 BIOMODELS SAME_URI
http://purl.obolibrary.org/obo/CHEBI_3048 CIDO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_3048 CHEBI SAME_URI
http://purl.bioontology.org/ontology/NDFRT/N0000147723 NDFRT LOOM
http://purl.obolibrary.org/obo/OMIT_0002955 OMIT LOOM
http://purl.bioontology.org/ontology/LNC/MTHU019541 LOINC LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000147723 INBANCIDO LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000147723 CIDO LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0005098 OCHV LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61649 NCIT LOOM
http://stirdf.jst.go.jp/id/200907098862701046 IOBC LOOM
http://purl.bioontology.org/ontology/RXNORM/1424 RXNORM LOOM
http://purl.bioontology.org/ontology/RCD/x01DT RCD LOOM
http://purl.obolibrary.org/obo/NCIT_C61649 BERO LOOM
http://purl.jp/bio/4/id/200906033175029097 IOBC LOOM
http://www.semanticweb.org/ontologies/2011/1/Ontology1296772722296.owl#EPO_00000064 PDON LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.605.869.270 RH-MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D001590 RH-MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.145.074.722.270 RH-MESH LOOM
http://purl.bioontology.org/ontology/CSP/3002-3254 CRISP LOOM
http://purl.bioontology.org/ontology/LNC/LP17858-9 LOINC LOOM
http://purl.obolibrary.org/obo/MESH_D001590 BERO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D04.075.080.875.099.722.270 RH-MESH LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#1802 OCHV LOOM
http://purl.bioontology.org/ontology/VANDF/4019630 VANDF LOOM
http://www.phoc.org.cn/pmo/class/PMO_00016243 PMAPP-PMO LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/372846002 SNOMEDCT LOOM
http://www.gamuts.net/entity#benztropine GAMUTS LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.132.889.244 RH-MESH LOOM
http://purl.bioontology.org/ontology/MESH/D001590 MESH LOOM
http://purl.obolibrary.org/obo/CHEBI_3048 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_3048 INBANCIDO LOOM
http://purl.obolibrary.org/obo/CHEBI_3048 CIDO LOOM
http://purl.bioontology.org/ontology/SNMI/C-67510 SNMI LOOM