Preferred Name |
bromfenac |
|
Synonyms |
[2-amino-3-(4-bromobenzoyl)phenyl]acetic acid bromfenacum 2-amino-3-(4-bromobenzoyl)benzeneacetic acid [2-Amino-3-(4-bromo-benzoyl)-phenyl]-acetic acid bromfenac bromfenaco |
|
Definitions |
Amfenac in which the the hydrogen at the 4 position of the benzoyl group is substituted by bromine. It is used for the management of ocular pain and treatment of postoperative inflammation in patients who have undergone cataract extraction. It was withdrawn from the US market in 1998, following concerns over off-label abuse and hepatic failure. |
|
ID |
http://purl.obolibrary.org/obo/CHEBI_240107 |
|
charge |
0 |
|
database_cross_reference |
Wikipedia:Bromfenac KEGG:D07541 LINCS:LSM-5585 Drug_Central:401 Beilstein:8335547 Patent:US4683242 DrugBank:DB00963 Patent:EP221753 CAS:91714-94-2 |
|
definition |
Amfenac in which the the hydrogen at the 4 position of the benzoyl group is substituted by bromine. It is used for the management of ocular pain and treatment of postoperative inflammation in patients who have undergone cataract extraction. It was withdrawn from the US market in 1998, following concerns over off-label abuse and hepatic failure. |
|
formula |
C15H12BrNO3 |
|
has functional parent | ||
has role | ||
has_exact_synonym |
[2-amino-3-(4-bromobenzoyl)phenyl]acetic acid |
|
has_obo_namespace |
chebi_ontology |
|
has_related_synonym |
bromfenacum 2-amino-3-(4-bromobenzoyl)benzeneacetic acid [2-Amino-3-(4-bromo-benzoyl)-phenyl]-acetic acid bromfenac bromfenaco |
|
has_RxCUI |
19737 |
|
id |
CHEBI:240107 |
|
in_subset | ||
inchi |
InChI=1S/C15H12BrNO3/c16-11-6-4-9(5-7-11)15(20)12-3-1-2-10(14(12)17)8-13(18)19/h1-7H,8,17H2,(H,18,19) |
|
inchikey |
ZBPLOVFIXSTCRZ-UHFFFAOYSA-N |
|
is conjugate acid of | ||
label |
bromfenac |
|
mass |
334.16500 |
|
monoisotopicmass |
333.00006 |
|
notation |
CHEBI:240107 |
|
prefLabel |
bromfenac |
|
smiles |
Nc1c(CC(O)=O)cccc1C(=O)c1ccc(Br)cc1 |
|
subClassOf |
http://purl.obolibrary.org/obo/CHEBI_33856 http://purl.obolibrary.org/obo/CHEBI_37141 |