The Drug Ontology

Last uploaded: February 15, 2019
Preferred Name

Cefotaxime

Synonyms

cefotaxima

cefotaximum

C16H17N5O7S2

(6R,7R)-3-Acetoxymethyl-7-{2-(2-amino-thiazol-4-yl)-2-[(Z)-methoxyimino]-acetylamino}-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid

(6R,7R,Z)-3-(acetoxymethyl)-7-(2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetamido)-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid

InChIKey=GPRBEKHLDVQUJE-QSWIMTSFSA-N

cefotaxime

[H][C@]12SCC(COC(C)=O)=C(N1C(=O)[C@H]2NC(=O)C(=N/OC)c1csc(N)n1)C(O)=O

Cephotaxime

(6R,7R)-3-(acetoxymethyl)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

3-(acetoxymethyl)-7beta-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3,4-didehydrocepham-4-carboxylic acid

InChI=1S/C16H17N5O7S2/c1-6(22)28-3-7-4-29-14-10(13(24)21(14)11(7)15(25)26)19-12(23)9(20-27-2)8-5-30-16(17)18-8/h5,10,14H,3-4H2,1-2H3,(H2,17,18)(H,19,23)(H,25,26)/b20-9-/t10-,14-/m1/s1

Definitions

A cephalosporin compound having acetoxymethyl and [2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino side groups.

ID

http://purl.obolibrary.org/obo/CHEBI_204928

database_cross_reference

KEGG DRUG:63527-52-6

CiteXplore:1384868

CiteXplore:17006042

Patent:US4152432

ChEMBL:112504

CiteXplore:18611527

ChEMBL:11677129

DrugBank:63527-52-6

KEGG COMPOUND:63527-52-6

KEGG DRUG:D07647

ChemIDplus:63527-52-6

ChEMBL:1635063

CiteXplore:15164972

CiteXplore:17386217

CiteXplore:21425867

CiteXplore:14512220

CiteXplore:15361989

ChEMBL:10866367

CiteXplore:11034276

CiteXplore:11061623

PDBeChem:CE3

DrugBank:DB00493

CiteXplore:19741292

Patent:US4098888

KEGG COMPOUND:C06885

Reaxys:1096643

CiteXplore:15969234

Patent:DE2556736

Beilstein:1096643

Patent:DE2702501

CiteXplore:12833570

ChEMBL:204928

CiteXplore:1502708

Wikipedia:Cefotaxime

has_alternative_id

CHEBI:3497

CHEBI:41475

CHEBI:112504

has_exact_synonym

3-(acetoxymethyl)-7beta-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3,4-didehydrocepham-4-carboxylic acid

has_related_synonym

cefotaxima

cefotaximum

C16H17N5O7S2

(6R,7R)-3-Acetoxymethyl-7-{2-(2-amino-thiazol-4-yl)-2-[(Z)-methoxyimino]-acetylamino}-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid

(6R,7R,Z)-3-(acetoxymethyl)-7-(2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetamido)-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid

InChIKey=GPRBEKHLDVQUJE-QSWIMTSFSA-N

cefotaxime

[H][C@]12SCC(COC(C)=O)=C(N1C(=O)[C@H]2NC(=O)C(=N/OC)c1csc(N)n1)C(O)=O

Cephotaxime

(6R,7R)-3-(acetoxymethyl)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

InChI=1S/C16H17N5O7S2/c1-6(22)28-3-7-4-29-14-10(13(24)21(14)11(7)15(25)26)19-12(23)9(20-27-2)8-5-30-16(17)18-8/h5,10,14H,3-4H2,1-2H3,(H2,17,18)(H,19,23)(H,25,26)/b20-9-/t10-,14-/m1/s1

has_RxCUI

2186

id

CHEBI:204928

label

Cefotaxime

cefotaxime

notation

CHEBI:204928

prefixIRI

CHEBI:204928

prefLabel

Cefotaxime

textual definition

A cephalosporin compound having acetoxymethyl and [2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino side groups.

subClassOf

http://purl.obolibrary.org/obo/CHEBI_38418

http://purl.obolibrary.org/obo/CHEBI_23066

http://purl.obolibrary.org/obo/CHEBI_36816

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http://purl.bioontology.org/ontology/UATC/J01DD01 ATC LOOM
http://purl.bioontology.org/ontology/LNC/MTHU002074 LOINC LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/372704003 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/LNC/LP14831-9 LOINC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.886.665.074.190.190 RH-MESH LOOM
http://stirdf.jst.go.jp/id/200907009723540531 IOBC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.065.589.099.249.190.190 RH-MESH LOOM
http://purl.bioontology.org/ontology/NDDF/004845 NDDF LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C354 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C354 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C354 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C354 NCIT LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000039177 PDQ LOOM
http://purl.jp/bio/4/id/200906042877350186 IOBC LOOM
http://purl.bioontology.org/ontology/MESH/D002439 MESH LOOM
http://www.co-ode.org/ontologies/galen#Cefotaxime GALEN LOOM
http://purl.bioontology.org/ontology/SNMI/C-53530 SNMI LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147755 NDFRT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D04.075.080.875.099.221.249.190.190 RH-MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D002439 RH-MESH LOOM
http://purl.bioontology.org/ontology/RXNORM/2186 RXNORM LOOM
http://purl.obolibrary.org/obo/CHEBI_204928 GENEPIO LOOM
http://purl.obolibrary.org/obo/CHEBI_204928 GENEPIO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_204928 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_204928 BIOMODELS SAME_URI
http://purl.obolibrary.org/obo/CHEBI_204928 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_204928 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_204928 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_204928 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_204928 GENEPIO LOOM
http://purl.obolibrary.org/obo/CHEBI_204928 GENEPIO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_204928 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_204928 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_204928 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_204928 DINTO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_204928 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_204928 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_204928 NIFSTD LOOM
http://purl.obolibrary.org/obo/CHEBI_204928 NIFSTD SAME_URI
http://purl.bioontology.org/ontology/VANDF/4019663 VANDF LOOM
http://id.loc.gov/authorities/subjects/sh90001869 FAST-TOPICAL LOOM