The Drug Ontology

Last uploaded: February 15, 2019
Preferred Name

Norfloxacin

Synonyms

1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid

1,4-Dihydro-1-ethyl-6-fluoro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid

norfloxacino

norfloxacinum

1-ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid

InChIKey=OGJPXUAPXNRGGI-UHFFFAOYSA-N

NFLX

C16H18FN3O3

norfloxacin

CCn1cc(C(O)=O)c(=O)c2cc(F)c(cc12)N1CCNCC1

norfloxacine

InChI=1S/C16H18FN3O3/c1-2-19-9-11(16(22)23)15(21)10-7-12(17)14(8-13(10)19)20-5-3-18-4-6-20/h7-9,18H,2-6H2,1H3,(H,22,23)

1-Ethyl-6-fluor-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-chinolincarbonsaeure

Definitions

A synthetic fluoroquinolone with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin is bactericidal and its mode of action depends on blocking of bacterial DNA replication by binding itself to an enzyme called DNA gyrase.

ID

http://purl.obolibrary.org/obo/CHEBI_100246

database_cross_reference

KEGG COMPOUND:C06687

DrugBank:DB01059

CiteXplore:6211142

Patent:BE863429

CiteXplore:3317294

KEGG DRUG:D00210

Patent:US4292317

ChEMBL:100246

CiteXplore:6224685

ChemIDplus:70458-96-7

CiteXplore:6234465

Gmelin:1576626

Patent:DE2840910

CiteXplore:6454381

KEGG COMPOUND:70458-96-7

Patent:US4146719

Beilstein:567897

Wikipedia:Norfloxacin

CiteXplore:6461606

CiteXplore:3908074

has_alternative_id

CHEBI:7629

has_exact_synonym

1-ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid

has_related_synonym

1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid

1,4-Dihydro-1-ethyl-6-fluoro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid

norfloxacino

norfloxacinum

InChIKey=OGJPXUAPXNRGGI-UHFFFAOYSA-N

NFLX

C16H18FN3O3

norfloxacin

CCn1cc(C(O)=O)c(=O)c2cc(F)c(cc12)N1CCNCC1

norfloxacine

InChI=1S/C16H18FN3O3/c1-2-19-9-11(16(22)23)15(21)10-7-12(17)14(8-13(10)19)20-5-3-18-4-6-20/h7-9,18H,2-6H2,1H3,(H,22,23)

1-Ethyl-6-fluor-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-chinolincarbonsaeure

has_RxCUI

7517

id

CHEBI:100246

label

Norfloxacin

norfloxacin

notation

CHEBI:100246

prefixIRI

CHEBI:100246

prefLabel

Norfloxacin

textual definition

A synthetic fluoroquinolone with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin is bactericidal and its mode of action depends on blocking of bacterial DNA replication by binding itself to an enzyme called DNA gyrase.

subClassOf

http://purl.obolibrary.org/obo/CHEBI_46848

http://purl.obolibrary.org/obo/CHEBI_26512

http://purl.obolibrary.org/obo/CHEBI_23765

http://purl.obolibrary.org/obo/CHEBI_37143

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http://purl.obolibrary.org/obo/ARO_3000662 ARO LOOM
http://purl.obolibrary.org/obo/ARO_3000662 ARO LOOM
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http://www.co-ode.org/ontologies/galen#Norfloxacin GALEN LOOM
http://purl.bioontology.org/ontology/LNC/LP16156-9 LOINC LOOM
http://id.loc.gov/authorities/subjects/sh85092409 FAST-TOPICAL LOOM
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http://purl.bioontology.org/ontology/MESH/D009643 MESH LOOM
http://www.drugbank.ca/drugs/DB01059 FTC LOOM
http://d-nb.info/gnd/4243995-4 FAST-TOPICAL LOOM
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