The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
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Preferred Name

brentuximab vedotin
Synonyms
ID

http://purl.obolibrary.org/obo/dinto_DB08870
ATCCode

L01XC12
binds

http://purl.obolibrary.org/obo/dinto_2103
CASRN

914088-09-8
DBBrand

adcetris
DBSynonym

cac10-vcmmae

sgn-35
Definition

Brentuximag vedotin or Adcetris? is an antibody-drug conjugate that combines an anti-CD30 antibody and the drug monomethyl auristatin E (MMAE). It is an anti-neoplastic agent used in the treatment of Hodgkin lymphoma and systemic anaplastic large cell lymphoma. Brentuximag vedotin was approved in 2011, and in January 2012, the drug label was revised to include a boxed warning of progressive multifocal leukoencephalopathy and death following JC virus infection.
has pharmacological target

http://purl.obolibrary.org/obo/dinto_2103
inhibits

http://purl.obolibrary.org/obo/dinto_2990

http://purl.obolibrary.org/obo/dinto_0901
is metabolised by

http://purl.obolibrary.org/obo/dinto_2990

http://purl.obolibrary.org/obo/dinto_0901
is transported by

http://purl.obolibrary.org/obo/dinto_1440
label

brentuximab vedotin
may interact with

http://purl.obolibrary.org/obo/dinto_DB00108

http://purl.obolibrary.org/obo/CHEBI_61049

http://purl.obolibrary.org/obo/dinto_DB00290

http://purl.obolibrary.org/obo/dinto_DB00337
prefixIRI

obo2:dinto_DB08870
prefLabel

brentuximab vedotin
xref

RxList:http://www.rxlist.com/adcetris-drug.htm

Drugs.com:http://www.drugs.com/mtm/brentuximab-vedotin.html

Wikipedia:http://en.wikipedia.org/wiki/Brentuximab_vedotin
subClassOf

http://purl.obolibrary.org/obo/dinto_000055
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