The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Preferred Name

rilonacept

ID

http://purl.obolibrary.org/obo/dinto_DB06372

binds

http://purl.obolibrary.org/obo/dinto_1371

http://purl.obolibrary.org/obo/dinto_1811

http://purl.obolibrary.org/obo/dinto_1808

CASRN

501081-76-1

DBBrand

arcalyst

DBSynonym

interleukin-1 (il-1) trap

arcalyst

Definition

Rilonacept is a dimeric fusion protein consisting of portions of IL-1R and the IL-1R accessory protein linked to the Fc portion of immunoglobulin G1. Rilonacept functions as an interleukin 1 inhibitor and is used in the treatment of CAPS, also known as cryopyrin-associated periodic syndromes, including familial cold auto-inflammatory syndrome (FCAS) and Muckle-Wells Syndrome (MWS), in adults and children greater than 12 years old.

label

rilonacept

may interact with

http://purl.obolibrary.org/obo/dinto_DB00005

http://purl.obolibrary.org/obo/dinto_DB00098

http://purl.obolibrary.org/obo/dinto_DB00065

http://purl.obolibrary.org/obo/CHEBI_68478

http://purl.obolibrary.org/obo/dinto_DB05259

http://purl.obolibrary.org/obo/CHEBI_2948

http://purl.obolibrary.org/obo/dinto_DB00095

http://purl.obolibrary.org/obo/dinto_DB00092

http://purl.obolibrary.org/obo/dinto_DB00051

http://purl.obolibrary.org/obo/dinto_DB06674

http://purl.obolibrary.org/obo/CHEBI_8764

http://purl.obolibrary.org/obo/CHEBI_9513

http://purl.obolibrary.org/obo/CHEBI_61049

http://purl.obolibrary.org/obo/CHEBI_44185

http://purl.obolibrary.org/obo/dinto_DB00026

http://purl.obolibrary.org/obo/dinto_DB06681

http://purl.obolibrary.org/obo/dinto_DB00075

http://purl.obolibrary.org/obo/dinto_DB00074

http://purl.obolibrary.org/obo/dinto_DB06287

http://purl.obolibrary.org/obo/dinto_DB00111

http://purl.obolibrary.org/obo/CHEBI_6402

http://purl.obolibrary.org/obo/dinto_DB00072

http://purl.obolibrary.org/obo/dinto_DB06273

http://purl.obolibrary.org/obo/CHEBI_4031

http://purl.obolibrary.org/obo/dinto_DB06643

http://purl.obolibrary.org/obo/dinto_DB06168

http://purl.obolibrary.org/obo/CHEBI_5801

http://purl.obolibrary.org/obo/dinto_DB00004

http://purl.obolibrary.org/obo/CHEBI_9168

prefixIRI

obo2:dinto_DB06372

prefLabel

rilonacept

xref

Drugs.com:http://www.drugs.com/ppa/rilonacept.html

RxList:http://www.rxlist.com/arcalyst-drug.htm

Wikipedia:http://en.wikipedia.org/wiki/Rilonacept

National Drug Code Directory:61755-001-01

subClassOf

http://purl.obolibrary.org/obo/dinto_000055

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