The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Preferred Name

methaqualone

Synonyms

C16H14N2O

2-methyl-3-(2-methylphenyl)-3,4-dihydroquinazolin-4-one

ID

http://purl.obolibrary.org/obo/dinto_DB04833

ATCCode

N05CM01

CASRN

72-44-6

DBBrand

quaalude

Definition

Methaqualone is a sedative-hypnotic drug that is similar in effect to barbiturates, a general central nervous system depressant. The sedative-hypnotic activity was first noted by Indian researchers in the 1950s and in 1962 methaqualone itself was patented in the US by Wallace and Tiernan. Its use peaked in the early 1970s as a hypnotic, for the treatment of insomnia, and as a sedative and muscle relaxant. It has also been used illegally as a recreational drug, commonly known as Quaaludes, Sopors, Ludes or Mandrax (particularly in the 1970s in North America) depending on the manufacturer. Since at least 2001, it has been widely used in South Africa, where it is commonly referred to as "smarties" or "geluk-tablette" (meaning happy tablets). Clandestinely produced methaqualone is still seized by government agencies and police forces around the world. [Wikipedia]

InChI

InChI=1S/C16H14N2O/c1-11-7-3-6-10-15(11)18-12(2)17-14-9-5-4-8-13(14)16(18)19/h3-10H,1-2H3

InChIKey

InChIKey=JEYCTXHKTXCGPB-UHFFFAOYSA-N

is metabolised by

http://purl.obolibrary.org/obo/dinto_0901

label

methaqualone

prefixIRI

obo2:dinto_DB04833

prefLabel

methaqualone

SMILES

CC1=CC=CC=C1N1C(C)=NC2=CC=CC=C2C1=O

Synonym

C16H14N2O

2-methyl-3-(2-methylphenyl)-3,4-dihydroquinazolin-4-one

xref

PubChem Compound:6292

Drugs Product Database (DPD):2243257

BindingDB:50089081

PubChem Substance:46507178

Wikipedia:http://en.wikipedia.org/wiki/Methaqualone

ChemSpider:6055

subClassOf

http://purl.obolibrary.org/obo/dinto_000055

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http://purl.obolibrary.org/obo/CHEBI_6821 CHEBI LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0025627 OCHV LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D008702 RH-MESH LOOM
http://purl.bioontology.org/ontology/LNC/MTHU001003 LOINC LOOM
http://uri.neuinfo.org/nif/nifstd/nlx_chem_100307 NIFSTD LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/71813009 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/LNC/LP15016-6 LOINC LOOM
http://purl.jp/bio/4/id/200906089778236904 IOBC LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#8030 OCHV LOOM
http://purl.bioontology.org/ontology/VANDF/4027428 VANDF LOOM
http://purl.bioontology.org/ontology/MESH/D008702 MESH LOOM
http://purl.obolibrary.org/obo/NCIT_C640 BERO LOOM
https://go.drugbank.com/drugs/DB04833 MDM LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000176151 NDFRT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C640 NCIT LOOM
http://purl.obolibrary.org/obo/MESH_D008702 BERO LOOM
http://stirdf.jst.go.jp/id/200907096302698276 IOBC LOOM
http://purl.obolibrary.org/obo/CHEBI_6821 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_6821 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_6821 DRON LOOM
http://ontology.apa.org/apaonto/termsonlyOUT%20(5).owl#Methaqualone APAONTO LOOM
http://www.phoc.org.cn/pmo/class/PMO_00017882 PMAPP-PMO LOOM
http://purl.bioontology.org/ontology/NDDF/001434 NDDF LOOM
http://purl.bioontology.org/ontology/SNMI/C-64030 SNMI LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.438.786.830.666 RH-MESH LOOM
http://purl.bioontology.org/ontology/ATC/N05CM01 ATC LOOM
http://purl.obolibrary.org/obo/OMIT_0009763 OMIT LOOM
http://purl.bioontology.org/ontology/RXNORM/6823 RXNORM LOOM