The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Preferred Name

dehydroepiandrosterone

Synonyms

(1S,2R,5S,10R,11S,15S)-5-hydroxy-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-7-en-14-one

C19H28O2

ID

http://purl.obolibrary.org/obo/dinto_DB01708

ATCCode

A14AA07

CASRN

53-43-0

DBBrand

ovigyn-d

fidelin

DBSynonym

5-dhea

3-beta-hydroxy-5-androsten-17-one

prasterone

dhea

5-dehydroepiandrosterone

dha

Definition

Dehydroepiandrosterone (DHEA) is a major C19 steroid produced by the adrenal cortex. It is also produced in small quantities in the testis and the ovary. Dehydroepiandrosterone (DHEA) can be converted to testosterone; androstenedione; estradiol; and estrone. Most of DHEA is sulfated (dehydroepiandrosterone sulfate) before secretion. In the United States, DHEA or DHEAS have been advertised with claims that they may be beneficial for a wide variety of ailments. DHEA and DHEAS are readily available in the United States, where they are marketed as over-the-counter dietary supplements. In Canada, a prescription is required to buy DHEA.

InChI

InChI=1S/C19H28O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h3,13-16,20H,4-11H2,1-2H3/t13-,14-,15-,16-,18-,19-/m0/s1

InChIKey

InChIKey=FMGSKLZLMKYGDP-USOAJAOKSA-N

inhibits

http://purl.obolibrary.org/obo/dinto_1956

is metabolised by

http://purl.obolibrary.org/obo/dinto_1956

http://purl.obolibrary.org/obo/dinto_0901

label

dehydroepiandrosterone

prefixIRI

obo2:dinto_DB01708

prefLabel

dehydroepiandrosterone

related with

http://purl.obolibrary.org/obo/dinto_0806

http://purl.obolibrary.org/obo/dinto_0789

http://purl.obolibrary.org/obo/dinto_4257

http://purl.obolibrary.org/obo/dinto_2989

http://purl.obolibrary.org/obo/dinto_1662

SMILES

[H][C@@]12CCC(=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC=C2C[C@@]([H])(O)CC[C@]12C

Synonym

(1S,2R,5S,10R,11S,15S)-5-hydroxy-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-7-en-14-one

C19H28O2

xref

Wikipedia:http://en.wikipedia.org/wiki/Dehydroepiandrosterone

IUPHAR:2370

PDB:AND

Guide To Pharmacology:2370

PubChem Compound:5881

PubChem Substance:46508824

PharmGKB:PA451993

ChEBI:28689

ChemSpider:5670

subClassOf

http://purl.obolibrary.org/obo/dinto_000055

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http://purl.bioontology.org/ontology/NDFRT/N0000148779 NDFRT LOOM
http://purl.bioontology.org/ontology/MESH/D003687 MESH LOOM
http://id.loc.gov/authorities/subjects/sh90004019 FAST-TOPICAL LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0004598 DDO LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0004598 DMTO LOOM
http://stirdf.jst.go.jp/id/200907033803231457 IOBC LOOM
http://localhost/plosthes.2017-1#5823 PLOSTHES LOOM
http://purl.jp/bio/4/id/200906009425230836 IOBC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D06.472.334.851.968.952 RH-MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D04.808.578.502.400 RH-MESH LOOM
http://purl.bioontology.org/ontology/RCD/X80FW RCD LOOM
http://purl.bioontology.org/ontology/VANDF/4021360 VANDF LOOM
http://purl.bioontology.org/ontology/SNMI/F-B2830 SNMI LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D06.472.040.502.400 RH-MESH LOOM
http://www.co-ode.org/ontologies/galen#Dehydroepiandrosterone GALEN LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000042419 PDQ LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/78316004 SNOMEDCT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D003687 RH-MESH LOOM
http://purl.bioontology.org/ontology/LNC/MTHU003476 LOINC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D04.808.054.079.429.625 RH-MESH LOOM
http://www.drugbank.ca/drugs/DB01708 FTC LOOM
http://purl.obolibrary.org/obo/CHEBI_28689 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_28689 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_28689 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_28689 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_28689 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_28689 UPHENO LOOM
http://purl.obolibrary.org/obo/CHEBI_28689 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_28689 HINO LOOM
http://purl.obolibrary.org/obo/CHEBI_28689 EFO LOOM
http://purl.bioontology.org/ontology/LNC/LP15528-0 LOINC LOOM
http://purl.bioontology.org/ontology/CSP/0171-4928 CRISP LOOM