The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Preferred Name

temafloxacin

Synonyms

1-(2,4-difluorophenyl)-6-fluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

C21H18F3N3O3

ID

http://purl.obolibrary.org/obo/dinto_DB01405

ATCCode

J01MA05

CASRN

108319-06-8

DBBrand

omniflox

DBSynonym

temafloxacina [spanish]

temafloxacinum [latin]

temafloxacine [french]

temafloxacin hydrochloride

Definition

Temafloxacin is a fluoroquinolone antibiotic drug which was withdrawn from sale in the U.S. shortly after its approval in 1992 because of serious adverse reactions resulting in three deaths. [Wikipedia]

has pharmacological target

http://purl.obolibrary.org/obo/dinto_0551

http://purl.obolibrary.org/obo/dinto_1028

InChI

InChI=1S/C21H18F3N3O3/c1-11-9-26(5-4-25-11)19-8-18-13(7-16(19)24)20(28)14(21(29)30)10-27(18)17-3-2-12(22)6-15(17)23/h2-3,6-8,10-11,25H,4-5,9H2,1H3,(H,29,30)

InChIKey

InChIKey=QKDHBVNJCZBTMR-UHFFFAOYSA-N

inhibits

http://purl.obolibrary.org/obo/dinto_0551

http://purl.obolibrary.org/obo/dinto_2651

http://purl.obolibrary.org/obo/dinto_1028

is metabolised by

http://purl.obolibrary.org/obo/dinto_2651

label

temafloxacin

may interact with

http://purl.obolibrary.org/obo/dinto_DB00893

http://purl.obolibrary.org/obo/dinto_DB01378

http://purl.obolibrary.org/obo/dinto_DB01373

prefixIRI

obo2:dinto_DB01405

prefLabel

temafloxacin

SMILES

CC1CN(CCN1)C1=C(F)C=C2C(=O)C(=CN(C2=C1)C1=C(F)C=C(F)C=C1)C(O)=O

Synonym

1-(2,4-difluorophenyl)-6-fluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

C21H18F3N3O3

xref

Wikipedia:http://en.wikipedia.org/wiki/Temafloxacin

ChemSpider:54143

PubChem Compound:60021

PubChem Substance:46508032

subClassOf

http://purl.obolibrary.org/obo/dinto_000055

Delete Subject Author Type Created
No notes to display