The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Preferred Name

lithium

Synonyms

lithium(1+) ion

Li

ID

http://purl.obolibrary.org/obo/dinto_DB01356

AHFScode

28:28.00

92:02.00*

ATCCode

D11AX04

N05AN01

CASRN

7439-93-2

DBBrand

lithotab

eskalith

Definition

Lithium was used during the 19th century to treat gout. Lithium salts such as lithium carbonate (Li2CO3), lithium citrate, and lithium orotate are mood stabilizers. They are used in the treatment of bipolar disorder, since unlike most other mood altering drugs, they counteract both mania and depression. Lithium can also be used to augment other antidepressant drugs. It is also sometimes prescribed as a preventive treatment for migraine disease and cluster headaches. The active principle in these salts is the lithium ion Li+, which having a smaller diameter, can easily displace K+ and Na+ and even Ca+2, in spite of its greater charge, occupying their sites in several critical neuronal enzymes and neurotransmitter receptors.

has effect

http://purl.obolibrary.org/obo/OAE_0000081

http://purl.obolibrary.org/obo/OAE_0001044

http://purl.obolibrary.org/obo/OAE_0000494

http://purl.obolibrary.org/obo/OAE_0000505

http://purl.obolibrary.org/obo/OAE_0001101

http://purl.obolibrary.org/obo/OAE_0000400

http://purl.obolibrary.org/obo/OAE_0000377

http://purl.obolibrary.org/obo/OAE_0000632

http://purl.obolibrary.org/obo/OAE_0000968

http://purl.obolibrary.org/obo/OAE_0000842

http://purl.obolibrary.org/obo/OAE_0000218

http://purl.obolibrary.org/obo/OAE_0001509

http://purl.obolibrary.org/obo/OAE_0000577

http://purl.obolibrary.org/obo/OAE_0001129

http://purl.obolibrary.org/obo/OAE_0000333

http://purl.obolibrary.org/obo/OAE_0000391

http://purl.obolibrary.org/obo/OAE_0000600

http://purl.obolibrary.org/obo/OAE_0000545

http://purl.obolibrary.org/obo/OAE_0000385

http://purl.obolibrary.org/obo/OAE_0000913

http://purl.obolibrary.org/obo/OAE_0000405

http://purl.obolibrary.org/obo/OAE_0000396

http://purl.obolibrary.org/obo/OAE_0000604

http://purl.obolibrary.org/obo/OAE_0000491

http://purl.obolibrary.org/obo/OAE_0000501

http://purl.obolibrary.org/obo/OAE_0000512

http://purl.obolibrary.org/obo/OAE_0001063

http://purl.obolibrary.org/obo/OAE_0000374

http://purl.obolibrary.org/obo/OAE_0000250

http://purl.obolibrary.org/obo/OAE_0001515

http://purl.obolibrary.org/obo/OAE_0000586

http://purl.obolibrary.org/obo/OAE_0000517

http://purl.obolibrary.org/obo/OAE_0000365

http://purl.obolibrary.org/obo/OAE_0000330

http://purl.obolibrary.org/obo/OAE_0000308

http://purl.obolibrary.org/obo/OAE_0000691

http://purl.obolibrary.org/obo/OAE_0001276

http://purl.obolibrary.org/obo/OAE_0000542

http://purl.obolibrary.org/obo/OAE_0000921

http://purl.obolibrary.org/obo/OAE_0000565

http://purl.obolibrary.org/obo/OAE_0000460

http://purl.obolibrary.org/obo/OAE_0000402

http://purl.obolibrary.org/obo/OAE_0000034

http://purl.obolibrary.org/obo/OAE_0000863

http://purl.obolibrary.org/obo/OAE_0000415

http://purl.obolibrary.org/obo/OAE_0000601

http://purl.obolibrary.org/obo/OAE_0000453

http://purl.obolibrary.org/obo/OAE_0000881

http://purl.obolibrary.org/obo/OAE_0001050

http://purl.obolibrary.org/obo/OAE_0000395

http://purl.obolibrary.org/obo/OAE_0000166

http://purl.obolibrary.org/obo/OAE_0000211

http://purl.obolibrary.org/obo/OAE_0000660

http://purl.obolibrary.org/obo/OAE_0000536

http://purl.obolibrary.org/obo/OAE_0000388

http://purl.obolibrary.org/obo/OAE_0000584

http://purl.obolibrary.org/obo/OAE_0001167

http://purl.obolibrary.org/obo/OAE_0000362

http://purl.obolibrary.org/obo/OAE_0000607

http://purl.obolibrary.org/obo/OAE_0000238

http://purl.obolibrary.org/obo/OAE_0000373

http://purl.obolibrary.org/obo/OAE_0000551

InChI

InChI=1S/Li/q+1

InChIKey

InChIKey=HBBGRARXTFLTSG-UHFFFAOYSA-N

inhibits

http://purl.obolibrary.org/obo/dinto_0530

http://purl.obolibrary.org/obo/dinto_2572

http://purl.obolibrary.org/obo/dinto_1986

label

lithium

may interact with

http://purl.obolibrary.org/obo/dinto_DB01324

http://purl.obolibrary.org/obo/CHEBI_72014

http://purl.obolibrary.org/obo/dinto_DB00519

http://purl.obolibrary.org/obo/CHEBI_8249

http://purl.obolibrary.org/obo/dinto_DB01345

http://purl.obolibrary.org/obo/CHEBI_28177

http://purl.obolibrary.org/obo/dinto_DB00469

http://purl.obolibrary.org/obo/CHEBI_9434

http://purl.obolibrary.org/obo/CHEBI_6128

http://purl.obolibrary.org/obo/dinto_DB01342

http://purl.obolibrary.org/obo/dinto_DB00465

http://purl.obolibrary.org/obo/CHEBI_64354

http://purl.obolibrary.org/obo/CHEBI_63631

http://purl.obolibrary.org/obo/CHEBI_31547

http://purl.obolibrary.org/obo/CHEBI_6909

http://purl.obolibrary.org/obo/CHEBI_5118

http://purl.obolibrary.org/obo/CHEBI_9943

http://purl.obolibrary.org/obo/CHEBI_3380

http://purl.obolibrary.org/obo/dinto_DB01340

http://purl.obolibrary.org/obo/CHEBI_8774

http://purl.obolibrary.org/obo/CHEBI_9927

http://purl.obolibrary.org/obo/CHEBI_41423

http://purl.obolibrary.org/obo/dinto_DB00310

http://purl.obolibrary.org/obo/CHEBI_3640

http://purl.obolibrary.org/obo/dinto_DB00232

http://purl.obolibrary.org/obo/CHEBI_3347

http://purl.obolibrary.org/obo/CHEBI_7476

http://purl.obolibrary.org/obo/CHEBI_5613

http://purl.obolibrary.org/obo/CHEBI_5138

http://purl.obolibrary.org/obo/dinto_DB00752

http://purl.obolibrary.org/obo/dinto_DB06700

http://purl.obolibrary.org/obo/dinto_DB00784

http://purl.obolibrary.org/obo/CHEBI_6339

http://purl.obolibrary.org/obo/CHEBI_8024

http://purl.obolibrary.org/obo/CHEBI_32139

http://purl.obolibrary.org/obo/dinto_DB00691

http://purl.obolibrary.org/obo/CHEBI_10650

http://purl.obolibrary.org/obo/CHEBI_5855

http://purl.obolibrary.org/obo/CHEBI_3013

http://purl.obolibrary.org/obo/dinto_DB01223

http://purl.obolibrary.org/obo/CHEBI_3047

http://purl.obolibrary.org/obo/CHEBI_5893

http://purl.obolibrary.org/obo/CHEBI_4814

http://purl.obolibrary.org/obo/CHEBI_9948

http://purl.obolibrary.org/obo/dinto_DB01303

http://purl.obolibrary.org/obo/dinto_DB01021

http://purl.obolibrary.org/obo/CHEBI_39669

http://purl.obolibrary.org/obo/CHEBI_48574

http://purl.obolibrary.org/obo/CHEBI_5959

http://purl.obolibrary.org/obo/CHEBI_4728

http://purl.obolibrary.org/obo/CHEBI_10124

http://purl.obolibrary.org/obo/CHEBI_68845

http://purl.obolibrary.org/obo/CHEBI_9654

http://purl.obolibrary.org/obo/CHEBI_43755

http://purl.obolibrary.org/obo/dinto_DB00726

http://purl.obolibrary.org/obo/CHEBI_8887

http://purl.obolibrary.org/obo/CHEBI_6541

http://purl.obolibrary.org/obo/dinto_DB00814

http://purl.obolibrary.org/obo/CHEBI_47381

http://purl.obolibrary.org/obo/CHEBI_63634

http://purl.obolibrary.org/obo/CHEBI_5163

http://purl.obolibrary.org/obo/CHEBI_27732

http://purl.obolibrary.org/obo/CHEBI_73044

http://purl.obolibrary.org/obo/CHEBI_8713

http://purl.obolibrary.org/obo/dinto_DB00999

http://purl.obolibrary.org/obo/CHEBI_31448

http://purl.obolibrary.org/obo/dinto_DB00774

http://purl.obolibrary.org/obo/CHEBI_9467

http://purl.obolibrary.org/obo/dinto_DB00684

http://purl.obolibrary.org/obo/CHEBI_49662

http://purl.obolibrary.org/obo/dinto_DB01105

http://purl.obolibrary.org/obo/CHEBI_3011

http://purl.obolibrary.org/obo/dinto_DB04272

http://purl.obolibrary.org/obo/dinto_DB01348

http://purl.obolibrary.org/obo/CHEBI_61058

http://purl.obolibrary.org/obo/dinto_DB01347

http://purl.obolibrary.org/obo/dinto_DB01325

http://purl.obolibrary.org/obo/CHEBI_4784

http://purl.obolibrary.org/obo/CHEBI_32221

http://purl.obolibrary.org/obo/dinto_DB01349

prefixIRI

obo2:dinto_DB01356

prefLabel

lithium

related with

http://purl.obolibrary.org/obo/dinto_2219

SMILES

[Li+]

Synonym

lithium(1+) ion

Li

xref

Drugs Product Database (DPD):236683

ChEBI:49713

PharmGKB:PA450243

RxList:http://www.rxlist.com/cgi/generic/lithium.htm

Wikipedia:http://en.wikipedia.org/wiki/Lithium

Drugs.com:http://www.drugs.com/lithium.html

PubChem Compound:28486

ChemSpider:26502

PubChem Substance:46505392

subClassOf

http://purl.obolibrary.org/obo/dinto_000055

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http://www.projecthalo.com/aura#Lithium AURA LOOM
http://bmi.utah.edu/ontologies/hfontology/C0023870 HFO LOOM
http://purl.jp/bio/4/id/200906085842861324 IOBC LOOM
http://id.loc.gov/authorities/subjects/sh85077577 FAST-TOPICAL LOOM
http://www.case.edu/EpSO.owl#Lithium EPSO LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C95186 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C95186 NCIT LOOM
http://www.drugbank.ca/drugs/DB01356 FTC LOOM
http://purl.bioontology.org/ontology/LNC/LP16175-9 LOINC LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0004035 FASTO LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0004035 DDO LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0004035 DMTO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D01.552.528.480 RH-MESH LOOM
http://doe-generated-ontology.com/OntoAD#C0023870 ONTOAD LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D008094 RH-MESH LOOM
http://scai.fraunhofer.de/AlzheimerOntology#lithium ADO LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147892 NDFRT LOOM
http://purl.bioontology.org/ontology/npo#NPO_782 NPO LOOM
http://purl.bioontology.org/ontology/NDDF/001532 NDDF LOOM
http://ontology.apa.org/apaonto/termsonlyOUT%20(5).owl#Lithium APAONTO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D01.268.549.450 RH-MESH LOOM
http://www.semanticweb.org/tome/ontologies/2015/7/Richfields#lithium ISO-FOOD LOOM
http://purl.bioontology.org/ontology/MESH/D008094 MESH LOOM
http://localhost/plosthes.2017-1#4001 PLOSTHES LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/85899009 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/RXNORM/6448 RXNORM LOOM
http://purl.obolibrary.org/obo/CHEBI_30145 CHEAR LOOM
http://purl.bioontology.org/ontology/CPT/80178 CPT LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#7490 OCHV LOOM
http://purl.bioontology.org/ontology/CSP/1852-6098 CRISP LOOM
http://www.stanford.edu/~coulet/phare.owl#Lithium PHARE LOOM
http://data.bnf.fr/ark:/12148/cb119338639 FAST-TOPICAL LOOM
http://radlex.org/RID/RID11766 RADLEX LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0023870 OCHV LOOM
http://www.co-ode.org/ontologies/galen#Lithium GALEN LOOM
http://purl.bioontology.org/ontology/RCD/XM0lB RCD LOOM
http://purl.bioontology.org/ontology/UATC/N05AN01 ATC LOOM
http://purl.bioontology.org/ontology/LNC/MTHU004197 LOINC LOOM
http://d-nb.info/gnd/4036037-4 FAST-TOPICAL LOOM
http://purl.bioontology.org/ontology/VANDF/4019803 VANDF LOOM