loading...| Preferred Name |
eculizumab |
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| Synonyms |
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| ID |
http://purl.obolibrary.org/obo/dinto_DB01257 |
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| CASRN |
219685-50-4 |
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| DBBrand |
soliris (alexion pharmaceuticals) soliris |
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| DBSynonym |
5g1.1 |
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| Definition |
Soliris is a formulation of eculizumab which is a recombinant humanized monoclonal IgG2/4; and kappa; antibody produced by murine myeloma cell culture and purified by standard bioprocess technology. Eculizumab contains human constant regions from human IgG2 sequences and human IgG4 sequences and murine complementarity-determining regions grafted onto the human framework light- and heavy-chain variable regions. Eculizumab is composed of two 448 amino acid heavy chains and two 214 amino acid light chains and has a molecular weight of approximately 148 kDa. |
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| has pharmacological target | ||
| label |
eculizumab |
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| prefixIRI |
obo2:dinto_DB01257 |
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| prefLabel |
eculizumab |
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| related with | ||
| xref |
RxList:http://www.rxlist.com/cgi/generic/soliris.htm Wikipedia:http://en.wikipedia.org/wiki/Eculizumab PharmGKB:PA164776637 National Drug Code Directory:25682-001-01 Drugs.com:http://www.drugs.com/cdi/eculizumab.html |
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| subClassOf |