The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Preferred Name

amiodarone

Synonyms

C25H29I2NO3

(2-{4-[(2-butyl-1-benzofuran-3-yl)carbonyl]-2,6-diiodophenoxy}ethyl)diethylamine

ID

http://purl.obolibrary.org/obo/dinto_DB01118

AHFScode

24:04.04.20

ATCCode

C01BD01

blocks

http://purl.obolibrary.org/obo/dinto_2907

CASRN

1951-25-3

DBBrand

amiodarons

arycor

aminodarone

amio-aqueous iv

pms-amiodarone

aratac

cordarone intravenous

labaz

cordarone

pacerone

DBSynonym

amiodarone hydrochloride

amiodarone hcl

amiodarone base

amiodarona [inn-spanish]

amiodaronum [inn-latin]

Definition

An antianginal and antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting Na,K-activated myocardial adenosine triphosphatase. There is a resulting decrease in heart rate and in vascular resistance. [PubChem]

has effect

http://purl.obolibrary.org/obo/OAE_0000081

http://purl.obolibrary.org/obo/OAE_0000505

http://purl.obolibrary.org/obo/OAE_0000770

http://purl.obolibrary.org/obo/OAE_0001300

http://purl.obolibrary.org/obo/OAE_0000390

http://purl.obolibrary.org/obo/OAE_0000185

http://purl.obolibrary.org/obo/OAE_0000377

http://purl.obolibrary.org/obo/OAE_0001345

http://purl.obolibrary.org/obo/OAE_0001205

http://purl.obolibrary.org/obo/OAE_0000842

http://purl.obolibrary.org/obo/OAE_0000218

http://purl.obolibrary.org/obo/OAE_0001509

http://purl.obolibrary.org/obo/OAE_0000577

http://purl.obolibrary.org/obo/OAE_0000449

http://purl.obolibrary.org/obo/OAE_0001035

http://purl.obolibrary.org/obo/OAE_0000920

http://purl.obolibrary.org/obo/OAE_0001024

http://purl.obolibrary.org/obo/OAE_0001403

http://purl.obolibrary.org/obo/OAE_0000659

http://purl.obolibrary.org/obo/OAE_0001045

http://purl.obolibrary.org/obo/OAE_0000333

http://purl.obolibrary.org/obo/OAE_0001448

http://purl.obolibrary.org/obo/OAE_0001449

http://purl.obolibrary.org/obo/OAE_0000268

http://purl.obolibrary.org/obo/OAE_0000600

http://purl.obolibrary.org/obo/OAE_0000197

http://purl.obolibrary.org/obo/OAE_0000557

http://purl.obolibrary.org/obo/OAE_0001013

http://purl.obolibrary.org/obo/OAE_0000866

http://purl.obolibrary.org/obo/OAE_0000396

http://purl.obolibrary.org/obo/OAE_0000418

http://purl.obolibrary.org/obo/OAE_0000434

http://purl.obolibrary.org/obo/OAE_0001135

http://purl.obolibrary.org/obo/OAE_0000512

http://purl.obolibrary.org/obo/OAE_0000780

http://purl.obolibrary.org/obo/OAE_0001063

http://purl.obolibrary.org/obo/OAE_0000287

http://purl.obolibrary.org/obo/OAE_0001378

http://purl.obolibrary.org/obo/OAE_0000374

http://purl.obolibrary.org/obo/OAE_0000630

http://purl.obolibrary.org/obo/OAE_0001297

http://purl.obolibrary.org/obo/OAE_0001341

http://purl.obolibrary.org/obo/OAE_0000617

http://purl.obolibrary.org/obo/OAE_0000169

http://purl.obolibrary.org/obo/OAE_0002206

http://purl.obolibrary.org/obo/OAE_0001364

http://purl.obolibrary.org/obo/OAE_0000260

http://purl.obolibrary.org/obo/OAE_0000506

http://purl.obolibrary.org/obo/OAE_0001505

http://purl.obolibrary.org/obo/OAE_0001008

http://purl.obolibrary.org/obo/OAE_0000308

http://purl.obolibrary.org/obo/OAE_0001369

http://purl.obolibrary.org/obo/OAE_0001253

http://purl.obolibrary.org/obo/OAE_0001275

http://purl.obolibrary.org/obo/OAE_0000376

http://purl.obolibrary.org/obo/OAE_0001217

http://purl.obolibrary.org/obo/OAE_0000194

http://purl.obolibrary.org/obo/OAE_0001298

http://purl.obolibrary.org/obo/OAE_0001276

http://purl.obolibrary.org/obo/OAE_0001463

http://purl.obolibrary.org/obo/OAE_0000911

http://purl.obolibrary.org/obo/OAE_0000542

http://purl.obolibrary.org/obo/OAE_0000195

http://purl.obolibrary.org/obo/OAE_0000921

http://purl.obolibrary.org/obo/OAE_0000382

http://purl.obolibrary.org/obo/OAE_0000565

http://purl.obolibrary.org/obo/OAE_0000460

http://purl.obolibrary.org/obo/OAE_0000402

http://purl.obolibrary.org/obo/OAE_0000034

http://purl.obolibrary.org/obo/OAE_0000021

http://purl.obolibrary.org/obo/OAE_0000415

http://purl.obolibrary.org/obo/OAE_0000601

http://purl.obolibrary.org/obo/OAE_0000310

http://purl.obolibrary.org/obo/OAE_0000645

http://purl.obolibrary.org/obo/OAE_0000453

http://purl.obolibrary.org/obo/OAE_0000647

http://purl.obolibrary.org/obo/OAE_0000881

http://purl.obolibrary.org/obo/OAE_0000510

http://purl.obolibrary.org/obo/OAE_0001155

http://purl.obolibrary.org/obo/OAE_0000454

http://purl.obolibrary.org/obo/OAE_0000086

http://purl.obolibrary.org/obo/OAE_0000905

http://purl.obolibrary.org/obo/OAE_0000166

http://purl.obolibrary.org/obo/OAE_0000602

http://purl.obolibrary.org/obo/OAE_0000525

http://purl.obolibrary.org/obo/OAE_0000210

http://purl.obolibrary.org/obo/OAE_0000388

http://purl.obolibrary.org/obo/OAE_0000835

http://purl.obolibrary.org/obo/OAE_0000779

http://purl.obolibrary.org/obo/OAE_0001365

http://purl.obolibrary.org/obo/OAE_0000362

http://purl.obolibrary.org/obo/OAE_0000304

http://purl.obolibrary.org/obo/OAE_0001145

http://purl.obolibrary.org/obo/OAE_0001366

http://purl.obolibrary.org/obo/OAE_0000607

http://purl.obolibrary.org/obo/OAE_0000238

http://purl.obolibrary.org/obo/OAE_0001238

http://purl.obolibrary.org/obo/OAE_0000373

http://purl.obolibrary.org/obo/OAE_0000551

has pharmacological target

http://purl.obolibrary.org/obo/dinto_2907

http://purl.obolibrary.org/obo/dinto_3113

http://purl.obolibrary.org/obo/dinto_3187

InChI

InChI=1S/C25H29I2NO3/c1-4-7-11-22-23(18-10-8-9-12-21(18)31-22)24(29)17-15-19(26)25(20(27)16-17)30-14-13-28(5-2)6-3/h8-10,12,15-16H,4-7,11,13-14H2,1-3H3

InChIKey

InChIKey=IYIKLHRQXLHMJQ-UHFFFAOYSA-N

induces

http://purl.obolibrary.org/obo/dinto_1440

inhibits

http://purl.obolibrary.org/obo/dinto_2058

http://purl.obolibrary.org/obo/dinto_1956

http://purl.obolibrary.org/obo/dinto_2990

http://purl.obolibrary.org/obo/dinto_0901

http://purl.obolibrary.org/obo/dinto_2993

http://purl.obolibrary.org/obo/dinto_1440

http://purl.obolibrary.org/obo/dinto_2260

http://purl.obolibrary.org/obo/dinto_3113

http://purl.obolibrary.org/obo/dinto_2651

http://purl.obolibrary.org/obo/dinto_3187

is metabolised by

http://purl.obolibrary.org/obo/dinto_2058

http://purl.obolibrary.org/obo/dinto_0901

http://purl.obolibrary.org/obo/dinto_0269

http://purl.obolibrary.org/obo/dinto_0291

http://purl.obolibrary.org/obo/dinto_2993

http://purl.obolibrary.org/obo/dinto_2651

http://purl.obolibrary.org/obo/dinto_1221

label

amiodarone

may interact with

http://purl.obolibrary.org/obo/CHEBI_46295

http://purl.obolibrary.org/obo/dinto_DB01346

http://purl.obolibrary.org/obo/CHEBI_10033

http://purl.obolibrary.org/obo/CHEBI_5280

http://purl.obolibrary.org/obo/dinto_DB01320

http://purl.obolibrary.org/obo/dinto_DB00503

http://purl.obolibrary.org/obo/CHEBI_63621

http://purl.obolibrary.org/obo/dinto_DB00199

http://purl.obolibrary.org/obo/CHEBI_195280

http://purl.obolibrary.org/obo/CHEBI_63632

http://purl.obolibrary.org/obo/dinto_DB00224

http://purl.obolibrary.org/obo/CHEBI_3732

http://purl.obolibrary.org/obo/CHEBI_4551

http://purl.obolibrary.org/obo/CHEBI_4513

http://purl.obolibrary.org/obo/CHEBI_37924

http://purl.obolibrary.org/obo/CHEBI_127342

http://purl.obolibrary.org/obo/CHEBI_28077

http://purl.obolibrary.org/obo/CHEBI_8428

http://purl.obolibrary.org/obo/dinto_DB00220

http://purl.obolibrary.org/obo/CHEBI_71226

http://purl.obolibrary.org/obo/dinto_DB01341

http://purl.obolibrary.org/obo/CHEBI_63611

http://purl.obolibrary.org/obo/dinto_DB06210

http://purl.obolibrary.org/obo/CHEBI_32250

http://purl.obolibrary.org/obo/dinto_DB00243

http://purl.obolibrary.org/obo/CHEBI_40050

http://purl.obolibrary.org/obo/CHEBI_9566

http://purl.obolibrary.org/obo/dinto_DB00976

http://purl.obolibrary.org/obo/CHEBI_45716

http://purl.obolibrary.org/obo/dinto_DB01208

http://purl.obolibrary.org/obo/CHEBI_101278

http://purl.obolibrary.org/obo/CHEBI_61049

http://purl.obolibrary.org/obo/CHEBI_59594

http://purl.obolibrary.org/obo/dinto_DB01319

http://purl.obolibrary.org/obo/CHEBI_51364

http://purl.obolibrary.org/obo/CHEBI_70746

http://purl.obolibrary.org/obo/CHEBI_6780

http://purl.obolibrary.org/obo/CHEBI_9948

http://purl.obolibrary.org/obo/CHEBI_9635

http://purl.obolibrary.org/obo/CHEBI_63628

http://purl.obolibrary.org/obo/CHEBI_3720

http://purl.obolibrary.org/obo/CHEBI_41774

http://purl.obolibrary.org/obo/CHEBI_133809

http://purl.obolibrary.org/obo/CHEBI_119915

http://purl.obolibrary.org/obo/CHEBI_63115

http://purl.obolibrary.org/obo/CHEBI_9654

http://purl.obolibrary.org/obo/dinto_DB06274

http://purl.obolibrary.org/obo/CHEBI_28593

http://purl.obolibrary.org/obo/dinto_DB00726

http://purl.obolibrary.org/obo/dinto_DB01623

http://purl.obolibrary.org/obo/dinto_DB00342

http://purl.obolibrary.org/obo/dinto_DB00532

http://purl.obolibrary.org/obo/CHEBI_4031

http://purl.obolibrary.org/obo/dinto_DB01362

http://purl.obolibrary.org/obo/CHEBI_9622

http://purl.obolibrary.org/obo/CHEBI_9150

http://purl.obolibrary.org/obo/dinto_DB00365

http://purl.obolibrary.org/obo/CHEBI_47657

http://purl.obolibrary.org/obo/dinto_DB00582

http://purl.obolibrary.org/obo/CHEBI_53766

http://purl.obolibrary.org/obo/CHEBI_10119

http://purl.obolibrary.org/obo/CHEBI_75984

http://purl.obolibrary.org/obo/CHEBI_68575

http://purl.obolibrary.org/obo/CHEBI_156095

http://purl.obolibrary.org/obo/CHEBI_9398

http://purl.obolibrary.org/obo/CHEBI_8107

http://purl.obolibrary.org/obo/CHEBI_63598

http://purl.obolibrary.org/obo/CHEBI_4888

http://purl.obolibrary.org/obo/CHEBI_63629

prefixIRI

obo2:dinto_DB01118

prefLabel

amiodarone

SMILES

CCCCC1=C(C(=O)C2=CC(I)=C(OCCN(CC)CC)C(I)=C2)C2=CC=CC=C2O1

Synonym

C25H29I2NO3

(2-{4-[(2-butyl-1-benzofuran-3-yl)carbonyl]-2,6-diiodophenoxy}ethyl)diethylamine

xref

ChemSpider:2072

Drugs.com:http://www.drugs.com/amiodarone.html

Drugs Product Database (DPD):2243836

BindingDB:18957

National Drug Code Directory:0703-1332-03

IUPHAR:2566

PubChem Compound:2157

RxList:http://www.rxlist.com/cgi/generic/amiodarone.htm

Wikipedia:http://en.wikipedia.org/wiki/Amiodarone

PharmGKB:PA448383

ChEBI:2663

PubChem Substance:46507387

Guide To Pharmacology:2566

subClassOf

http://purl.obolibrary.org/obo/dinto_000055

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http://purl.bioontology.org/ontology/MESH/D000638 MESH LOOM
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