Preferred Name |
butenafine |
|
Synonyms |
C23H27N [(4-tert-butylphenyl)methyl](methyl)(naphthalen-1-ylmethyl)amine |
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ID |
http://purl.obolibrary.org/obo/dinto_DB01091 |
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ATCCode |
D01AE23 |
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CASRN |
101828-21-1 |
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DBBrand |
mentax |
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DBSynonym |
butenafina [inn-spanish] butenafine [inn] butenafine hcl butenafine hydrochloride butenafinum [inn-latin] |
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Definition |
Butenafine hydrochloride is a synthetic benzylamine antifungal agent. Butenafine works by inhibiting the synthesis of sterols by inhibiting squalene epoxidase, an enzyme responsible for the creation of sterols needed in fungal cell membranes. |
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has effect |
http://purl.obolibrary.org/obo/OAE_0000308 |
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has pharmacological target | ||
InChI |
InChI=1S/C23H27N/c1-23(2,3)21-14-12-18(13-15-21)16-24(4)17-20-10-7-9-19-8-5-6-11-22(19)20/h5-15H,16-17H2,1-4H3 |
|
InChIKey |
InChIKey=ABJKWBDEJIDSJZ-UHFFFAOYSA-N |
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inhibits | ||
label |
butenafine |
|
prefixIRI |
obo2:dinto_DB01091 |
|
prefLabel |
butenafine |
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SMILES |
CN(CC1=CC=C(C=C1)C(C)(C)C)CC1=CC=CC2=CC=CC=C12 |
|
Synonym |
C23H27N [(4-tert-butylphenyl)methyl](methyl)(naphthalen-1-ylmethyl)amine |
|
xref |
Drugs.com:http://www.drugs.com/cdi/butenafine-cream.html Drugs Product Database (DPD):2231063 National Drug Code Directory:0378-6151-46 PubChem Substance:46506191 PubChem Compound:2484 PharmGKB:PA164745478 RxList:http://www.rxlist.com/cgi/generic2/butenafine.htm ChEBI:3238 Wikipedia:http://en.wikipedia.org/wiki/Butenafine ChemSpider:2390 |
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subClassOf |