The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Preferred Name

butenafine

Synonyms

C23H27N

[(4-tert-butylphenyl)methyl](methyl)(naphthalen-1-ylmethyl)amine

ID

http://purl.obolibrary.org/obo/dinto_DB01091

ATCCode

D01AE23

CASRN

101828-21-1

DBBrand

mentax

DBSynonym

butenafina [inn-spanish]

butenafine [inn]

butenafine hcl

butenafine hydrochloride

butenafinum [inn-latin]

Definition

Butenafine hydrochloride is a synthetic benzylamine antifungal agent. Butenafine works by inhibiting the synthesis of sterols by inhibiting squalene epoxidase, an enzyme responsible for the creation of sterols needed in fungal cell membranes.

has effect

http://purl.obolibrary.org/obo/OAE_0000308

http://purl.obolibrary.org/obo/OAE_0000086

http://purl.obolibrary.org/obo/OAE_0000645

has pharmacological target

http://purl.obolibrary.org/obo/dinto_4017

InChI

InChI=1S/C23H27N/c1-23(2,3)21-14-12-18(13-15-21)16-24(4)17-20-10-7-9-19-8-5-6-11-22(19)20/h5-15H,16-17H2,1-4H3

InChIKey

InChIKey=ABJKWBDEJIDSJZ-UHFFFAOYSA-N

inhibits

http://purl.obolibrary.org/obo/dinto_4017

label

butenafine

prefixIRI

obo2:dinto_DB01091

prefLabel

butenafine

SMILES

CN(CC1=CC=C(C=C1)C(C)(C)C)CC1=CC=CC2=CC=CC=C12

Synonym

C23H27N

[(4-tert-butylphenyl)methyl](methyl)(naphthalen-1-ylmethyl)amine

xref

Drugs.com:http://www.drugs.com/cdi/butenafine-cream.html

Drugs Product Database (DPD):2231063

National Drug Code Directory:0378-6151-46

PubChem Substance:46506191

PubChem Compound:2484

PharmGKB:PA164745478

RxList:http://www.rxlist.com/cgi/generic2/butenafine.htm

ChEBI:3238

Wikipedia:http://en.wikipedia.org/wiki/Butenafine

ChemSpider:2390

subClassOf

http://purl.obolibrary.org/obo/dinto_000055

Delete Subject Author Type Created
No notes to display