The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

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Preferred Name	pilocarpine
Synonyms	C11H16N2O2 (3S,4R)-3-ethyl-4-[(1-methyl-1H-imidazol-5-yl)methyl]oxolan-2-one
ID	http://purl.obolibrary.org/obo/dinto_DB01085
activates	http://purl.obolibrary.org/obo/dinto_3182 http://purl.obolibrary.org/obo/dinto_1005 http://purl.obolibrary.org/obo/dinto_3887
AHFScode	92:02.00* 12:04.00 52:20.00
ATCCode	N07AX01 S01EB01
CASRN	54-71-7
DBBrand	pilocar epicar isoptocarpine pilagan sno pilo amistura p pilocel syncarpine piloptic-1 piloptic-4 ocu-carpine pilopine hs mi-pilo ophth sol ami-pilo pilocarpol ocusert pilo-40 piloptic-6 piloptic-3 pilovisc minims pilocarpine salagen ocusert p 20 piloptic-2 miocarpine pilomiotin pilokarpol pilostat ocusert pilo mistura p pilocarpal pilocar smp p.v. carpine liquifilm akarpine ocusert pilo-20 piloptic-1/2 almocarpine isopto carpine mi-pilo
DBSynonym	pilocarpine hcl beta-pilocarpine hydrochloride pilocarpine muriate pilocarpine hydrochloride spersacarpine hydrochloride pilocarpine monohydrochloride spersacarpine pilokarpin adsorbocarpine pilocarpin pilokarpin monohydrochloride pilocarpine chloride
Definition	A slowly hydrolyzed muscarinic agonist with no nicotinic effects. Pilocarpine is used as a miotic and in the treatment of glaucoma. [PubChem]
has effect	http://purl.obolibrary.org/obo/OAE_0000388 http://purl.obolibrary.org/obo/OAE_0000496 http://purl.obolibrary.org/obo/OAE_0000447 http://purl.obolibrary.org/obo/OAE_0000453 http://purl.obolibrary.org/obo/OAE_0000597 http://purl.obolibrary.org/obo/OAE_0000081 http://purl.obolibrary.org/obo/OAE_0000573 http://purl.obolibrary.org/obo/OAE_0000604 http://purl.obolibrary.org/obo/OAE_0000905 http://purl.obolibrary.org/obo/OAE_0000377 http://purl.obolibrary.org/obo/OAE_0001510 http://purl.obolibrary.org/obo/OAE_0000902 http://purl.obolibrary.org/obo/OAE_0000391 http://purl.obolibrary.org/obo/OAE_0000218 http://purl.obolibrary.org/obo/OAE_0000479 http://purl.obolibrary.org/obo/OAE_0000492 http://purl.obolibrary.org/obo/OAE_0000596 http://purl.obolibrary.org/obo/OAE_0000406 http://purl.obolibrary.org/obo/OAE_0000561 http://purl.obolibrary.org/obo/OAE_0000825 http://purl.obolibrary.org/obo/OAE_0001509 http://purl.obolibrary.org/obo/OAE_0000493 http://purl.obolibrary.org/obo/OAE_0000443 http://purl.obolibrary.org/obo/OAE_0001186 http://purl.obolibrary.org/obo/OAE_0000512 http://purl.obolibrary.org/obo/OAE_0000308 http://purl.obolibrary.org/obo/OAE_0000567 http://purl.obolibrary.org/obo/OAE_0000415 http://purl.obolibrary.org/obo/OAE_0000195 http://purl.obolibrary.org/obo/OAE_0000373 http://purl.obolibrary.org/obo/OAE_0000210 http://purl.obolibrary.org/obo/OAE_0000319 http://purl.obolibrary.org/obo/OAE_0000021 http://purl.obolibrary.org/obo/OAE_0000412 http://purl.obolibrary.org/obo/OAE_0000465 http://purl.obolibrary.org/obo/OAE_0001448 http://purl.obolibrary.org/obo/OAE_0000317 http://purl.obolibrary.org/obo/OAE_0000660 http://purl.obolibrary.org/obo/OAE_0001280 http://purl.obolibrary.org/obo/OAE_0000382 http://purl.obolibrary.org/obo/OAE_0000935 http://purl.obolibrary.org/obo/OAE_0000677 http://purl.obolibrary.org/obo/OAE_0000365 http://purl.obolibrary.org/obo/OAE_0000600 http://purl.obolibrary.org/obo/OAE_0000310 http://purl.obolibrary.org/obo/OAE_0000426 http://purl.obolibrary.org/obo/OAE_0000608 http://purl.obolibrary.org/obo/OAE_0000518 http://purl.obolibrary.org/obo/OAE_0000632 http://purl.obolibrary.org/obo/OAE_0000690 http://purl.obolibrary.org/obo/OAE_0000601 http://purl.obolibrary.org/obo/OAE_0001463 http://purl.obolibrary.org/obo/OAE_0000375 http://purl.obolibrary.org/obo/OAE_0000300 http://purl.obolibrary.org/obo/OAE_0000386 http://purl.obolibrary.org/obo/OAE_0000551 http://purl.obolibrary.org/obo/OAE_0000691 http://purl.obolibrary.org/obo/OAE_0000455 http://purl.obolibrary.org/obo/OAE_0001234 http://purl.obolibrary.org/obo/OAE_0000498 http://purl.obolibrary.org/obo/OAE_0000502 http://purl.obolibrary.org/obo/OAE_0001420 http://purl.obolibrary.org/obo/OAE_0000312 http://purl.obolibrary.org/obo/OAE_0001014 http://purl.obolibrary.org/obo/OAE_0001057 http://purl.obolibrary.org/obo/OAE_0001295 http://purl.obolibrary.org/obo/OAE_0000400 http://purl.obolibrary.org/obo/OAE_0000086 http://purl.obolibrary.org/obo/OAE_0000645 http://purl.obolibrary.org/obo/OAE_0000584 http://purl.obolibrary.org/obo/OAE_0001129 http://purl.obolibrary.org/obo/OAE_0002206 http://purl.obolibrary.org/obo/OAE_0000894 http://purl.obolibrary.org/obo/OAE_0000473 http://purl.obolibrary.org/obo/OAE_0000414 http://purl.obolibrary.org/obo/OAE_0000607 http://purl.obolibrary.org/obo/OAE_0000355 http://purl.obolibrary.org/obo/OAE_0000789 http://purl.obolibrary.org/obo/OAE_0000038 http://purl.obolibrary.org/obo/OAE_0000968 http://purl.obolibrary.org/obo/OAE_0000166 http://purl.obolibrary.org/obo/OAE_0002122 http://purl.obolibrary.org/obo/OAE_0000866 http://purl.obolibrary.org/obo/OAE_0000508 http://purl.obolibrary.org/obo/OAE_0000401 http://purl.obolibrary.org/obo/OAE_0000343 http://purl.obolibrary.org/obo/OAE_0000405 http://purl.obolibrary.org/obo/OAE_0000536 http://purl.obolibrary.org/obo/OAE_0000647 http://purl.obolibrary.org/obo/OAE_0000385 http://purl.obolibrary.org/obo/OAE_0000185 http://purl.obolibrary.org/obo/OAE_0000602 http://purl.obolibrary.org/obo/OAE_0001147 http://purl.obolibrary.org/obo/OAE_0000396 http://purl.obolibrary.org/obo/OAE_0000362 http://purl.obolibrary.org/obo/OAE_0000470 http://purl.obolibrary.org/obo/OAE_0000374 http://purl.obolibrary.org/obo/OAE_0001166 http://purl.obolibrary.org/obo/OAE_0000394 http://purl.obolibrary.org/obo/OAE_0000211 http://purl.obolibrary.org/obo/OAE_0000462 http://purl.obolibrary.org/obo/OAE_0000466 http://purl.obolibrary.org/obo/OAE_0001309 http://purl.obolibrary.org/obo/OAE_0001170 http://purl.obolibrary.org/obo/OAE_0000766 http://purl.obolibrary.org/obo/OAE_0001458 http://purl.obolibrary.org/obo/OAE_0000513 http://purl.obolibrary.org/obo/OAE_0000402 http://purl.obolibrary.org/obo/OAE_0000350
has pharmacological target	http://purl.obolibrary.org/obo/dinto_3182 http://purl.obolibrary.org/obo/dinto_1005 http://purl.obolibrary.org/obo/dinto_3887
InChI	InChI=1S/C11H16N2O2/c1-3-10-8(6-15-11(10)14)4-9-5-12-7-13(9)2/h5,7-8,10H,3-4,6H2,1-2H3/t8-,10-/m0/s1
InChIKey	InChIKey=QCHFTSOMWOSFHM-WPRPVWTQSA-N
inhibits	http://purl.obolibrary.org/obo/dinto_0901 http://purl.obolibrary.org/obo/dinto_2496
is metabolised by	http://purl.obolibrary.org/obo/dinto_0293 http://purl.obolibrary.org/obo/dinto_0901 http://purl.obolibrary.org/obo/dinto_2496
label	pilocarpine
may interact with	http://purl.obolibrary.org/obo/dinto_DB00382
prefixIRI	obo2:dinto_DB01085
prefLabel	pilocarpine
SMILES	CC[C@H]1[C@@H](CC2=CN=CN2C)COC1=O
Synonym	C11H16N2O2 (3S,4R)-3-ethyl-4-[(1-methyl-1H-imidazol-5-yl)methyl]oxolan-2-one
xref	PubChem Compound:5910 Drugs.com:http://www.drugs.com/cdi/pilocarpine-drops.html Guide To Pharmacology:305 Drugs Product Database (DPD):2229556 RxList:http://www.rxlist.com/cgi/generic3/salagen.htm PubChem Substance:46507475 Wikipedia:http://en.wikipedia.org/wiki/Pilocarpine IUPHAR:305 ChemSpider:5699 ChEBI:39462 PharmGKB:PA450962 National Drug Code Directory:0065-0215-35
subClassOf	http://purl.obolibrary.org/obo/dinto_000055

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Mapping To	Ontology	Source
http://purl.obolibrary.org/obo/XCO_0000888	XCO	LOOM
http://purl.obolibrary.org/obo/CHEBI_8207	CHEBI	LOOM
http://purl.obolibrary.org/obo/CHEBI_39464	CHEBI	LOOM
http://purl.obolibrary.org/obo/CHEBI_39462	CHEBI	LOOM
http://purl.obolibrary.org/obo/NCIT_C62068	BERO	LOOM
http://purl.bioontology.org/ontology/RXNORM/8328	RXNORM	LOOM
http://www.drugbank.ca/drugs/DB01085	FTC	LOOM
http://purl.bioontology.org/ontology/RCD/k8d..	RCD	LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000146543	NDFRT	LOOM
http://purl.bioontology.org/ontology/SNMI/C-97770	SNMI	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D010862	RH-MESH	LOOM
http://purl.bioontology.org/ontology/VANDF/4018209	VANDF	LOOM
http://purl.obolibrary.org/obo/CHEBI_8207	BERO	LOOM
http://purl.obolibrary.org/obo/CHEBI_8207	BIOMODELS	LOOM
http://purl.obolibrary.org/obo/OMIT_0011840	OMIT	LOOM
https://go.drugbank.com/drugs/DB01085	MDM	LOOM
http://purl.jp/bio/4/id/200906027254541917	IOBC	LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/372895002	SNOMEDCT	LOOM
http://purl.obolibrary.org/obo/CHEBI_39464	BERO	LOOM
http://purl.obolibrary.org/obo/CHEBI_39464	BIOMODELS	LOOM
http://purl.obolibrary.org/obo/CHEBI_39462	PDRO	LOOM
http://purl.obolibrary.org/obo/CHEBI_39462	BERO	LOOM
http://purl.obolibrary.org/obo/CHEBI_39462	BIOMODELS	LOOM
http://purl.obolibrary.org/obo/CHEBI_39462	DRON	LOOM
http://purl.obolibrary.org/obo/CHEBI_39462	NIFSTD	LOOM
http://purl.bioontology.org/ontology/ATC/S01EB01	ATC	LOOM
http://purl.bioontology.org/ontology/NDDF/001693	NDDF	LOOM
http://purl.obolibrary.org/obo/MESH_D010862	BERO	LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C62068	NCIT	LOOM
http://purl.bioontology.org/ontology/ATC/N07AX01	ATC	LOOM
http://stirdf.jst.go.jp/id/200907029874836425	IOBC	LOOM
http://www.co-ode.org/ontologies/galen#Pilocarpine	GALEN	LOOM
http://www.phoc.org.cn/pmo/class/PMO_00018123	PMAPP-PMO	LOOM
http://ontology.apa.org/apaonto/termsonlyOUT%20(5).owl#Pilocarpine	APAONTO	LOOM
http://purl.bioontology.org/ontology/CSP/0092-9479	CRISP	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.132.672	RH-MESH	LOOM
http://purl.bioontology.org/ontology/MESH/D010862	MESH	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0031923	OCHV	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#9735	OCHV	LOOM