The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Jump to:
loading...
Preferred Name

terbinafine
Synonyms

C21H25N

[(2E)-6,6-dimethylhept-2-en-4-yn-1-yl](methyl)(naphthalen-1-ylmethyl)amine
ID

http://purl.obolibrary.org/obo/dinto_DB00857
AHFScode

84:04.08.04

08:14.04
ATCCode

D01AE15

D01BA02
CASRN

91161-71-6
DBBrand

bramazil

lamasil

terbina

lamisil

lamisil at

lamisil oral

terbifoam
DBSynonym

terbinafine hcl

terbinafine hydrochloride

ternbinafine hcl
Definition

Terbinafine hydrochloride (Lamisil) is a synthetic allylamine antifungal. It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues. Like other allylamines, terbinafine inhibits ergosterol synthesis by inhibiting the fungal squalene monooxygenase (squalene 2,3-epoxidase), an enzyme that is part of the fungal cell wall synthesis pathway.
has effect

http://purl.obolibrary.org/obo/OAE_0000238

http://purl.obolibrary.org/obo/OAE_0000388

http://purl.obolibrary.org/obo/OAE_0000449

http://purl.obolibrary.org/obo/OAE_0000453

http://purl.obolibrary.org/obo/OAE_0000905

http://purl.obolibrary.org/obo/OAE_0000377

http://purl.obolibrary.org/obo/OAE_0001510

http://purl.obolibrary.org/obo/OAE_0000376

http://purl.obolibrary.org/obo/OAE_0000596

http://purl.obolibrary.org/obo/OAE_0000308

http://purl.obolibrary.org/obo/OAE_0000415

http://purl.obolibrary.org/obo/OAE_0000195

http://purl.obolibrary.org/obo/OAE_0000319

http://purl.obolibrary.org/obo/OAE_0001448

http://purl.obolibrary.org/obo/OAE_0000317

http://purl.obolibrary.org/obo/OAE_0001397

http://purl.obolibrary.org/obo/OAE_0001025

http://purl.obolibrary.org/obo/OAE_0000600

http://purl.obolibrary.org/obo/OAE_0001378

http://purl.obolibrary.org/obo/OAE_0001026

http://purl.obolibrary.org/obo/OAE_0000632

http://purl.obolibrary.org/obo/OAE_0000601

http://purl.obolibrary.org/obo/OAE_0001463

http://purl.obolibrary.org/obo/OAE_0001357

http://purl.obolibrary.org/obo/OAE_0000375

http://purl.obolibrary.org/obo/OAE_0001275

http://purl.obolibrary.org/obo/OAE_0000687

http://purl.obolibrary.org/obo/OAE_0001057

http://purl.obolibrary.org/obo/OAE_0001295

http://purl.obolibrary.org/obo/OAE_0001425

http://purl.obolibrary.org/obo/OAE_0000268

http://purl.obolibrary.org/obo/OAE_0000086

http://purl.obolibrary.org/obo/OAE_0000645

http://purl.obolibrary.org/obo/OAE_0001135

http://purl.obolibrary.org/obo/OAE_0000968

http://purl.obolibrary.org/obo/OAE_0000034

http://purl.obolibrary.org/obo/OAE_0000536

http://purl.obolibrary.org/obo/OAE_0000505

http://purl.obolibrary.org/obo/OAE_0001356

http://purl.obolibrary.org/obo/OAE_0000385

http://purl.obolibrary.org/obo/OAE_0000468

http://purl.obolibrary.org/obo/OAE_0000487

http://purl.obolibrary.org/obo/OAE_0001217

http://purl.obolibrary.org/obo/OAE_0000396

http://purl.obolibrary.org/obo/OAE_0000390

http://purl.obolibrary.org/obo/OAE_0000362

http://purl.obolibrary.org/obo/OAE_0000565

http://purl.obolibrary.org/obo/OAE_0000374

http://purl.obolibrary.org/obo/OAE_0000299

http://purl.obolibrary.org/obo/OAE_0000480

http://purl.obolibrary.org/obo/OAE_0000402
has pharmacological target

http://purl.obolibrary.org/obo/dinto_4017
InChI

InChI=1S/C21H25N/c1-21(2,3)15-8-5-9-16-22(4)17-19-13-10-12-18-11-6-7-14-20(18)19/h5-7,9-14H,16-17H2,1-4H3/b9-5+
InChIKey

InChIKey=DOMXUEMWDBAQBQ-WEVVVXLNSA-N
induces

http://purl.obolibrary.org/obo/dinto_0901
inhibits

http://purl.obolibrary.org/obo/dinto_3102

http://purl.obolibrary.org/obo/dinto_2993

http://purl.obolibrary.org/obo/dinto_4017

http://purl.obolibrary.org/obo/dinto_0266
is metabolised by

http://purl.obolibrary.org/obo/dinto_2651

http://purl.obolibrary.org/obo/dinto_2058

http://purl.obolibrary.org/obo/dinto_0291

http://purl.obolibrary.org/obo/dinto_0901

http://purl.obolibrary.org/obo/dinto_1221

http://purl.obolibrary.org/obo/dinto_0938
label

terbinafine
may interact with

http://purl.obolibrary.org/obo/CHEBI_32250

http://purl.obolibrary.org/obo/dinto_DB01303

http://purl.obolibrary.org/obo/CHEBI_9943

http://purl.obolibrary.org/obo/CHEBI_16714

http://purl.obolibrary.org/obo/dinto_DB01621

http://purl.obolibrary.org/obo/CHEBI_127342

http://purl.obolibrary.org/obo/CHEBI_41774

http://purl.obolibrary.org/obo/dinto_DB01142

http://purl.obolibrary.org/obo/CHEBI_8028

http://purl.obolibrary.org/obo/CHEBI_7936

http://purl.obolibrary.org/obo/CHEBI_3647

http://purl.obolibrary.org/obo/CHEBI_8499

http://purl.obolibrary.org/obo/dinto_DB00476

http://purl.obolibrary.org/obo/dinto_DB00344

http://purl.obolibrary.org/obo/dinto_DB00540

http://purl.obolibrary.org/obo/dinto_DB01206

http://purl.obolibrary.org/obo/dinto_DB00997

http://purl.obolibrary.org/obo/dinto_DB01223

http://purl.obolibrary.org/obo/CHEBI_4031

http://purl.obolibrary.org/obo/CHEBI_8871

http://purl.obolibrary.org/obo/CHEBI_47499

http://purl.obolibrary.org/obo/CHEBI_45304

http://purl.obolibrary.org/obo/dinto_DB00726

http://purl.obolibrary.org/obo/CHEBI_5613

http://purl.obolibrary.org/obo/CHEBI_47780

http://purl.obolibrary.org/obo/CHEBI_7494

http://purl.obolibrary.org/obo/dinto_DB00373

http://purl.obolibrary.org/obo/CHEBI_9566

http://purl.obolibrary.org/obo/CHEBI_51364

http://purl.obolibrary.org/obo/CHEBI_3441

http://purl.obolibrary.org/obo/CHEBI_75984

http://purl.obolibrary.org/obo/CHEBI_5123

http://purl.obolibrary.org/obo/CHEBI_27732

http://purl.obolibrary.org/obo/dinto_DB00514

http://purl.obolibrary.org/obo/CHEBI_6916

http://purl.obolibrary.org/obo/CHEBI_5138

http://purl.obolibrary.org/obo/CHEBI_4728

http://purl.obolibrary.org/obo/CHEBI_3380

http://purl.obolibrary.org/obo/CHEBI_3638

http://purl.obolibrary.org/obo/CHEBI_8466

http://purl.obolibrary.org/obo/CHEBI_8461

http://purl.obolibrary.org/obo/CHEBI_6904

http://purl.obolibrary.org/obo/CHEBI_9622

http://purl.obolibrary.org/obo/CHEBI_45367

http://purl.obolibrary.org/obo/dinto_DB01577

http://purl.obolibrary.org/obo/CHEBI_9398

http://purl.obolibrary.org/obo/CHEBI_9467

http://purl.obolibrary.org/obo/dinto_DB01171

http://purl.obolibrary.org/obo/CHEBI_31236

http://purl.obolibrary.org/obo/CHEBI_9123

http://purl.obolibrary.org/obo/CHEBI_6950

http://purl.obolibrary.org/obo/CHEBI_8428

http://purl.obolibrary.org/obo/CHEBI_6456

http://purl.obolibrary.org/obo/CHEBI_28177

http://purl.obolibrary.org/obo/CHEBI_28077

http://purl.obolibrary.org/obo/CHEBI_47781

http://purl.obolibrary.org/obo/dinto_DB00934

http://purl.obolibrary.org/obo/CHEBI_2675

http://purl.obolibrary.org/obo/CHEBI_2666

http://purl.obolibrary.org/obo/CHEBI_5118
prefixIRI

obo2:dinto_DB00857
prefLabel

terbinafine
SMILES

CN(C\C=C\C#CC(C)(C)C)CC1=CC=CC2=CC=CC=C12
Synonym

C21H25N

[(2E)-6,6-dimethylhept-2-en-4-yn-1-yl](methyl)(naphthalen-1-ylmethyl)amine
xref

National Drug Code Directory:0378-5710-93

RxList:http://www.rxlist.com/cgi/generic/terbin.htm

Wikipedia:http://en.wikipedia.org/wiki/Terbinafine

PharmGKB:PA451614

Drugs Product Database (DPD):2240346

Drugs.com:http://www.drugs.com/cdi/terbinafine.html
subClassOf

http://purl.obolibrary.org/obo/dinto_000055
Add comment
Add proposal
Delete Subject Author Type Created
No notes to display
Create mapping

Delete Mapping To Ontology Source
http://purl.obolibrary.org/obo/CHEBI_9448 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_9448 FYPO LOOM
http://purl.obolibrary.org/obo/CHEBI_9448 OBA LOOM
http://purl.obolibrary.org/obo/CHEBI_9448 HOIP LOOM
http://purl.obolibrary.org/obo/CHEBI_9448 PHIPO LOOM
http://purl.obolibrary.org/obo/CHEBI_9448 CHEBI LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#14916 OCHV LOOM
http://www.drugbank.ca/drugs/DB00857 FTC LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000021605 NDFRT LOOM
http://purl.bioontology.org/ontology/RXNORM/37801 RXNORM LOOM
http://stirdf.jst.go.jp/id/200907095366807234 IOBC LOOM
http://purl.bioontology.org/ontology/LNC/LP14848-3 LOINC LOOM
http://purl.bioontology.org/ontology/VANDF/4023600 VANDF LOOM
http://www.co-ode.org/ontologies/galen#Terbinafine GALEN LOOM
http://purl.obolibrary.org/obo/ARO_3007507 ARO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C041359 RH-MESH LOOM
http://purl.obolibrary.org/obo/CHEBI_9448 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_9448 FIDEO LOOM
http://purl.obolibrary.org/obo/CHEBI_9448 COVID-19 LOOM
http://purl.obolibrary.org/obo/CHEBI_9448 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_9448 TXPO LOOM
http://purl.obolibrary.org/obo/CHEBI_9448 DRON LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C48019 NCIT LOOM
http://purl.obolibrary.org/obo/NCIT_C48019 BERO LOOM
http://purl.jp/bio/4/id/200906017874991755 IOBC LOOM
http://purl.bioontology.org/ontology/ATC/D01BA02 ATC LOOM
http://purl.bioontology.org/ontology/LNC/MTHU002062 LOINC LOOM
http://purl.bioontology.org/ontology/RCD/x03eY RCD LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0076110 OCHV LOOM
https://go.drugbank.com/drugs/DB00857 MDM LOOM
http://www.phoc.org.cn/pmo/class/PMO_00025785 PMAPP-PMO LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/373450007 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/ATC/D01AE15 ATC LOOM
http://purl.bioontology.org/ontology/MESH/D000077291 MESH LOOM