The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Preferred Name

haloprogin

Synonyms

1,2,4-trichloro-5-[(3-iodoprop-2-yn-1-yl)oxy]benzene

C9H4Cl3IO

ID

http://purl.obolibrary.org/obo/dinto_DB00793

ATCCode

D01AE11

CASRN

777-11-7

DBBrand

haloprogin [usan:inn:jan]

mycanden

haloprogina [inn-spanish]

haloproginum [inn-latin]

haloprogine [inn-french]

polik

aloprogen

mycilan

halotex

Definition

Haloprogin is used as a topical ointment or cream in the treatment of Tinea infections. Tinea infections are superficial fungal infections caused by three species of fungi collectively known as dermatophytes (Trichophyton, Microsporum and Epidermophyton). Commonly these infections are named for the body part affected, including tinea corporis (general skin), tinea cruris (groin), and tinea pedis (feet). Haloprogin is a halogenated phenolic ether administered topically for dermotaphytic infections. The mechanism of action is unknown, but it is thought to be via inhibition of oxygen uptake and disruption of yeast membrane structure and function.

InChI

InChI=1S/C9H4Cl3IO/c10-6-4-8(12)9(5-7(6)11)14-3-1-2-13/h4-5H,3H2

InChIKey

InChIKey=CTETYYAZBPJBHE-UHFFFAOYSA-N

label

haloprogin

prefixIRI

obo2:dinto_DB00793

prefLabel

haloprogin

SMILES

ClC1=CC(Cl)=C(Cl)C=C1OCC#CI

Synonym

1,2,4-trichloro-5-[(3-iodoprop-2-yn-1-yl)oxy]benzene

C9H4Cl3IO

xref

Wikipedia:http://en.wikipedia.org/wiki/Haloprogin

PubChem Substance:46504892

PubChem Compound:3561

BindingDB:50194601

Drugs.com:http://www.drugs.com/mtm/haloprogin-topical.html

ChemSpider:3440

PharmGKB:PA164768737

subClassOf

http://purl.obolibrary.org/obo/dinto_000055

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