The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Preferred Name

moexipril

Synonyms

C27H34N2O7

(3S)-2-[(2S)-2-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}propanoyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid

ID

http://purl.obolibrary.org/obo/dinto_DB00691

AHFScode

24:32.04

ATCCode

C09AA13

CASRN

103775-10-6

DBBrand

univasc

DBSynonym

moexipril hcl

moexiprilum [inn-latin]

moexipril hydrochloride

Definition

Moexipril is a non-sulfhydryl containing precursor of the active angiotensin-converting enzyme (ACE) inhibitor moexiprilat. It is used to treat high blood pressure (hypertension). It works by relaxing blood vessels, causing them to widen. Lowering high blood pressure helps prevent strokes, heart attacks and kidney problems.

has effect

http://purl.obolibrary.org/obo/OAE_0000505

http://purl.obolibrary.org/obo/OAE_0000400

http://purl.obolibrary.org/obo/OAE_0000770

http://purl.obolibrary.org/obo/OAE_0000390

http://purl.obolibrary.org/obo/OAE_0000401

http://purl.obolibrary.org/obo/OAE_0000377

http://purl.obolibrary.org/obo/OAE_0000567

http://purl.obolibrary.org/obo/OAE_0000300

http://purl.obolibrary.org/obo/OAE_0001046

http://purl.obolibrary.org/obo/OAE_0000600

http://purl.obolibrary.org/obo/OAE_0000534

http://purl.obolibrary.org/obo/OAE_0000385

http://purl.obolibrary.org/obo/OAE_0000406

http://purl.obolibrary.org/obo/OAE_0000375

http://purl.obolibrary.org/obo/OAE_0000374

http://purl.obolibrary.org/obo/OAE_0000343

http://purl.obolibrary.org/obo/OAE_0000319

http://purl.obolibrary.org/obo/OAE_0000376

http://purl.obolibrary.org/obo/OAE_0001217

http://purl.obolibrary.org/obo/OAE_0000195

http://purl.obolibrary.org/obo/OAE_0000402

http://purl.obolibrary.org/obo/OAE_0000034

http://purl.obolibrary.org/obo/OAE_0000021

http://purl.obolibrary.org/obo/OAE_0000415

http://purl.obolibrary.org/obo/OAE_0000601

http://purl.obolibrary.org/obo/OAE_0000310

http://purl.obolibrary.org/obo/OAE_0000453

http://purl.obolibrary.org/obo/OAE_0000647

http://purl.obolibrary.org/obo/OAE_0000038

http://purl.obolibrary.org/obo/OAE_0000350

http://purl.obolibrary.org/obo/OAE_0000602

http://purl.obolibrary.org/obo/OAE_0000210

http://purl.obolibrary.org/obo/OAE_0000388

http://purl.obolibrary.org/obo/OAE_0000584

http://purl.obolibrary.org/obo/OAE_0002122

http://purl.obolibrary.org/obo/OAE_0000362

http://purl.obolibrary.org/obo/OAE_0001309

http://purl.obolibrary.org/obo/OAE_0000607

http://purl.obolibrary.org/obo/OAE_0000373

http://purl.obolibrary.org/obo/OAE_0000551

has pharmacological target

http://purl.obolibrary.org/obo/dinto_2130

http://purl.obolibrary.org/obo/dinto_2574

InChI

InChI=1S/C27H34N2O7/c1-5-36-27(33)21(12-11-18-9-7-6-8-10-18)28-17(2)25(30)29-16-20-15-24(35-4)23(34-3)14-19(20)13-22(29)26(31)32/h6-10,14-15,17,21-22,28H,5,11-13,16H2,1-4H3,(H,31,32)/t17-,21-,22-/m0/s1

InChIKey

InChIKey=UWWDHYUMIORJTA-HSQYWUDLSA-N

inhibits

http://purl.obolibrary.org/obo/dinto_2130

http://purl.obolibrary.org/obo/dinto_2574

is transported by

http://purl.obolibrary.org/obo/dinto_2004

http://purl.obolibrary.org/obo/dinto_4065

label

moexipril

may interact with

http://purl.obolibrary.org/obo/CHEBI_68564

http://purl.obolibrary.org/obo/dinto_DB01345

http://purl.obolibrary.org/obo/dinto_DB00384

http://purl.obolibrary.org/obo/dinto_DB01369

http://purl.obolibrary.org/obo/dinto_DB01356

http://purl.obolibrary.org/obo/CHEBI_68845

http://purl.obolibrary.org/obo/CHEBI_2639

http://purl.obolibrary.org/obo/CHEBI_50861

http://purl.obolibrary.org/obo/CHEBI_63629

prefixIRI

obo2:dinto_DB00691

prefLabel

moexipril

SMILES

CCOC(=O)[C@H](CCC1=CC=CC=C1)N[C@@H](C)C(=O)N1CC2=CC(OC)=C(OC)C=C2C[C@H]1C(O)=O

Synonym

C27H34N2O7

(3S)-2-[(2S)-2-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}propanoyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid

xref

PDRhealth:http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/uni1468.shtml

PharmGKB:PA164769059

BindingDB:50084673

National Drug Code Directory:0574-0110-01

RxList:http://www.rxlist.com/cgi/generic2/moexip.htm

PubChem Substance:46508441

Wikipedia:http://en.wikipedia.org/wiki/Moexipril

Drugs.com:http://www.drugs.com/cdi/moexipril.html

PubChem Compound:91270

ChemSpider:82418

subClassOf

http://purl.obolibrary.org/obo/dinto_000055

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Delete Mapping To Ontology Source
http://purl.obolibrary.org/obo/DDO.owl#DDO_0005833 FASTO LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0005833 DDO LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0005833 DMTO LOOM
http://purl.bioontology.org/ontology/VANDF/4023996 VANDF LOOM
http://purl.bioontology.org/ontology/RXNORM/30131 NLMVS LOOM
http://purl.bioontology.org/ontology/RXNORM/30131 RXNORM LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C83967 NCIT LOOM
https://bioportal.bioontology.org/ontologies/FTDM.owl#moexipril FASTO LOOM
http://www.drugbank.ca/drugs/DB00691 FTC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C058302 RH-MESH LOOM
http://purl.obolibrary.org/obo/DRON_00011124 DRON LOOM
http://purl.bioontology.org/ontology/RCD/biA.. RCD LOOM
http://www.co-ode.org/ontologies/galen#Moexipril GALEN LOOM
http://purl.obolibrary.org/obo/XCO_0000589 XCO LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0066685 OCHV LOOM
http://purl.jp/bio/4/id/200906028405187416 IOBC LOOM
http://purl.bioontology.org/ontology/MESH/C058302 MESH LOOM
http://purl.obolibrary.org/obo/CHEBI_6960 CHEBI LOOM
http://purl.bioontology.org/ontology/UATC/C09AA13 ATC LOOM
http://stirdf.jst.go.jp/id/200907018645105695 IOBC LOOM
http://scai.fraunhofer.de/AlzheimerOntology#moexipril ADO LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/373442003 SNOMEDCT LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0005835 DDO LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0005835 DMTO LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000022001 NDFRT LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#14421 OCHV LOOM