Preferred Name |
mecamylamine |
|
Synonyms |
C11H21N N,2,3,3-tetramethylbicyclo[2.2.1]heptan-2-amine |
|
ID |
http://purl.obolibrary.org/obo/dinto_DB00657 |
|
ATCCode |
C02BB01 |
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CASRN |
60-40-2 |
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DBBrand |
mecamine versamine inversine mevasin hydrochloride mekamin hydrochloride mevasine inversine hydrochloride revertina mecamine hydrochloride mekamine |
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DBSynonym |
3-methylaminoisocamphane hydrochloride 2-methylamino-2,3,3-trimethylnorbornane 3-methylaminoisocamphane mecamilamina 2-methylaminoisocamphane mecamylamine hydrochloride |
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Definition |
A nicotinic antagonist that is well absorbed from the gastrointestinal tract and crosses the blood-brain barrier. Mecamylamine has been used as a ganglionic blocker in treating hypertension, but, like most ganglionic blockers, is more often used now as a research tool. [PubChem] |
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has effect |
http://purl.obolibrary.org/obo/OAE_0000388 http://purl.obolibrary.org/obo/OAE_0000589 http://purl.obolibrary.org/obo/OAE_0001509 http://purl.obolibrary.org/obo/OAE_0000921 http://purl.obolibrary.org/obo/OAE_0001489 http://purl.obolibrary.org/obo/OAE_0000600 http://purl.obolibrary.org/obo/OAE_0000601 http://purl.obolibrary.org/obo/OAE_0000551 http://purl.obolibrary.org/obo/OAE_0001068 http://purl.obolibrary.org/obo/OAE_0000400 http://purl.obolibrary.org/obo/OAE_0000034 http://purl.obolibrary.org/obo/OAE_0000166 http://purl.obolibrary.org/obo/OAE_0000505 http://purl.obolibrary.org/obo/OAE_0000306 http://purl.obolibrary.org/obo/OAE_0000602 |
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has pharmacological target | ||
InChI |
InChI=1S/C11H21N/c1-10(2)8-5-6-9(7-8)11(10,3)12-4/h8-9,12H,5-7H2,1-4H3 |
|
InChIKey |
InChIKey=IMYZQPCYWPFTAG-UHFFFAOYSA-N |
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inhibits | ||
label |
mecamylamine |
|
prefixIRI |
obo2:dinto_DB00657 |
|
prefLabel |
mecamylamine |
|
SMILES |
CNC1(C)C2CCC(C2)C1(C)C |
|
Synonym |
C11H21N N,2,3,3-tetramethylbicyclo[2.2.1]heptan-2-amine |
|
xref |
ChemSpider:3892 RxList:http://www.rxlist.com/cgi/generic2/mecamylamine.htm BindingDB:50061565 Guide To Pharmacology:3990 National Drug Code Directory:17205-0626-1 Wikipedia:http://en.wikipedia.org/wiki/Mecamylamine PubChem Compound:4032 PubChem Substance:46508607 PharmGKB:PA450334 IUPHAR:3990 |
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subClassOf |