The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Preferred Name

tacrine

Synonyms

1,2,3,4-tetrahydroacridin-9-amine

C13H14N2

ID

http://purl.obolibrary.org/obo/dinto_DB00382

ATCCode

N06DA01

N06AA18

CASRN

321-64-2

DBBrand

cognex

romotal

DBSynonym

tha

tetrahydroaminoacridine

tetrahydroaminocrine

tetrahydroaminacrine

tetrahydroaminocrin

Definition

A centerally active cholinesterase inhibitor that has been used to counter the effects of muscle relaxants, as a respiratory stimulant, and in the treatment of Alzheimer s disease and other central nervous system disorders. [PubChem]

has effect

http://purl.obolibrary.org/obo/OAE_0001436

http://purl.obolibrary.org/obo/OAE_0000355

http://purl.obolibrary.org/obo/OAE_0000573

http://purl.obolibrary.org/obo/OAE_0000411

http://purl.obolibrary.org/obo/OAE_0000400

http://purl.obolibrary.org/obo/OAE_0001421

http://purl.obolibrary.org/obo/OAE_0000309

http://purl.obolibrary.org/obo/OAE_0000356

http://purl.obolibrary.org/obo/OAE_0000390

http://purl.obolibrary.org/obo/OAE_0000401

http://purl.obolibrary.org/obo/OAE_0000772

http://purl.obolibrary.org/obo/OAE_0000377

http://purl.obolibrary.org/obo/OAE_0001345

http://purl.obolibrary.org/obo/OAE_0000632

http://purl.obolibrary.org/obo/OAE_0000205

http://purl.obolibrary.org/obo/OAE_0000968

http://purl.obolibrary.org/obo/OAE_0001205

http://purl.obolibrary.org/obo/OAE_0000608

http://purl.obolibrary.org/obo/OAE_0000567

http://purl.obolibrary.org/obo/OAE_0000218

http://purl.obolibrary.org/obo/OAE_0000577

http://purl.obolibrary.org/obo/OAE_0000462

http://purl.obolibrary.org/obo/OAE_0000473

http://purl.obolibrary.org/obo/OAE_0001129

http://purl.obolibrary.org/obo/OAE_0000496

http://purl.obolibrary.org/obo/OAE_0000659

http://purl.obolibrary.org/obo/OAE_0000391

http://purl.obolibrary.org/obo/OAE_0001448

http://purl.obolibrary.org/obo/OAE_0000898

http://purl.obolibrary.org/obo/OAE_0001327

http://purl.obolibrary.org/obo/OAE_0000300

http://purl.obolibrary.org/obo/OAE_0000716

http://purl.obolibrary.org/obo/OAE_0001291

http://purl.obolibrary.org/obo/OAE_0000600

http://purl.obolibrary.org/obo/OAE_0000611

http://purl.obolibrary.org/obo/OAE_0000902

http://purl.obolibrary.org/obo/OAE_0000197

http://purl.obolibrary.org/obo/OAE_0000545

http://purl.obolibrary.org/obo/OAE_0001142

http://purl.obolibrary.org/obo/OAE_0000534

http://purl.obolibrary.org/obo/OAE_0000385

http://purl.obolibrary.org/obo/OAE_0000581

http://purl.obolibrary.org/obo/OAE_0001489

http://purl.obolibrary.org/obo/OAE_0000406

http://purl.obolibrary.org/obo/OAE_0000789

http://purl.obolibrary.org/obo/OAE_0001013

http://purl.obolibrary.org/obo/OAE_0000396

http://purl.obolibrary.org/obo/OAE_0000418

http://purl.obolibrary.org/obo/OAE_0001340

http://purl.obolibrary.org/obo/OAE_0000766

http://purl.obolibrary.org/obo/OAE_0000604

http://purl.obolibrary.org/obo/OAE_0001755

http://purl.obolibrary.org/obo/OAE_0001339

http://purl.obolibrary.org/obo/OAE_0001373

http://purl.obolibrary.org/obo/OAE_0001234

http://purl.obolibrary.org/obo/OAE_0000895

http://purl.obolibrary.org/obo/OAE_0000596

http://purl.obolibrary.org/obo/OAE_0000491

http://purl.obolibrary.org/obo/OAE_0000894

http://purl.obolibrary.org/obo/OAE_0000501

http://purl.obolibrary.org/obo/OAE_0000512

http://purl.obolibrary.org/obo/OAE_0001098

http://purl.obolibrary.org/obo/OAE_0001063

http://purl.obolibrary.org/obo/OAE_0000317

http://purl.obolibrary.org/obo/OAE_0000375

http://purl.obolibrary.org/obo/OAE_0000306

http://purl.obolibrary.org/obo/OAE_0000479

http://purl.obolibrary.org/obo/OAE_0000374

http://purl.obolibrary.org/obo/OAE_0000250

http://purl.obolibrary.org/obo/OAE_0002206

http://purl.obolibrary.org/obo/OAE_0001364

http://purl.obolibrary.org/obo/OAE_0001515

http://purl.obolibrary.org/obo/OAE_0000539

http://purl.obolibrary.org/obo/OAE_0000586

http://purl.obolibrary.org/obo/OAE_0000967

http://purl.obolibrary.org/obo/OAE_0000470

http://purl.obolibrary.org/obo/OAE_0000873

http://purl.obolibrary.org/obo/OAE_0000482

http://purl.obolibrary.org/obo/OAE_0000424

http://purl.obolibrary.org/obo/OAE_0000885

http://purl.obolibrary.org/obo/OAE_0001147

http://purl.obolibrary.org/obo/OAE_0000597

http://purl.obolibrary.org/obo/OAE_0000492

http://purl.obolibrary.org/obo/OAE_0000365

http://purl.obolibrary.org/obo/OAE_0000701

http://purl.obolibrary.org/obo/OAE_0000343

http://purl.obolibrary.org/obo/OAE_0000447

http://purl.obolibrary.org/obo/OAE_0001275

http://purl.obolibrary.org/obo/OAE_0000376

http://purl.obolibrary.org/obo/OAE_0000194

http://purl.obolibrary.org/obo/OAE_0000487

http://purl.obolibrary.org/obo/OAE_0000542

http://purl.obolibrary.org/obo/OAE_0000508

http://purl.obolibrary.org/obo/OAE_0000195

http://purl.obolibrary.org/obo/OAE_0000921

http://purl.obolibrary.org/obo/OAE_0000382

http://purl.obolibrary.org/obo/OAE_0000403

http://purl.obolibrary.org/obo/OAE_0000414

http://purl.obolibrary.org/obo/OAE_0000358

http://purl.obolibrary.org/obo/OAE_0000762

http://purl.obolibrary.org/obo/OAE_0000460

http://purl.obolibrary.org/obo/OAE_0000402

http://purl.obolibrary.org/obo/OAE_0000034

http://purl.obolibrary.org/obo/OAE_0001751

http://purl.obolibrary.org/obo/OAE_0000021

http://purl.obolibrary.org/obo/OAE_0000415

http://purl.obolibrary.org/obo/OAE_0000601

http://purl.obolibrary.org/obo/OAE_0000310

http://purl.obolibrary.org/obo/OAE_0001336

http://purl.obolibrary.org/obo/OAE_0000453

http://purl.obolibrary.org/obo/OAE_0000647

http://purl.obolibrary.org/obo/OAE_0000038

http://purl.obolibrary.org/obo/OAE_0000498

http://purl.obolibrary.org/obo/OAE_0000394

http://purl.obolibrary.org/obo/OAE_0000086

http://purl.obolibrary.org/obo/OAE_0000350

http://purl.obolibrary.org/obo/OAE_0000687

http://purl.obolibrary.org/obo/OAE_0000905

http://purl.obolibrary.org/obo/OAE_0000166

http://purl.obolibrary.org/obo/OAE_0000211

http://purl.obolibrary.org/obo/OAE_0000671

http://purl.obolibrary.org/obo/OAE_0000602

http://purl.obolibrary.org/obo/OAE_0000525

http://purl.obolibrary.org/obo/OAE_0000536

http://purl.obolibrary.org/obo/OAE_0000527

http://purl.obolibrary.org/obo/OAE_0000561

http://purl.obolibrary.org/obo/OAE_0000388

http://purl.obolibrary.org/obo/OAE_0000526

http://purl.obolibrary.org/obo/OAE_0002122

http://purl.obolibrary.org/obo/OAE_0000779

http://purl.obolibrary.org/obo/OAE_0000362

http://purl.obolibrary.org/obo/OAE_0000304

http://purl.obolibrary.org/obo/OAE_0000340

http://purl.obolibrary.org/obo/OAE_0001309

http://purl.obolibrary.org/obo/OAE_0000607

http://purl.obolibrary.org/obo/OAE_0000618

http://purl.obolibrary.org/obo/OAE_0000238

http://purl.obolibrary.org/obo/OAE_0001529

http://purl.obolibrary.org/obo/OAE_0000373

http://purl.obolibrary.org/obo/OAE_0000551

has pharmacological target

http://purl.obolibrary.org/obo/dinto_1021

http://purl.obolibrary.org/obo/dinto_3568

InChI

InChI=1S/C13H14N2/c14-13-9-5-1-3-7-11(9)15-12-8-4-2-6-10(12)13/h1,3,5,7H,2,4,6,8H2,(H2,14,15)

InChIKey

InChIKey=YLJREFDVOIBQDA-UHFFFAOYSA-N

inhibits

http://purl.obolibrary.org/obo/dinto_1440

http://purl.obolibrary.org/obo/dinto_1021

http://purl.obolibrary.org/obo/dinto_3568

is metabolised by

http://purl.obolibrary.org/obo/dinto_2651

label

tacrine

may interact with

http://purl.obolibrary.org/obo/CHEBI_7856

http://purl.obolibrary.org/obo/dinto_DB00737

http://purl.obolibrary.org/obo/dinto_DB00427

http://purl.obolibrary.org/obo/CHEBI_51380

http://purl.obolibrary.org/obo/dinto_DB01619

http://purl.obolibrary.org/obo/CHEBI_8212

http://purl.obolibrary.org/obo/CHEBI_59177

http://purl.obolibrary.org/obo/dinto_DB01285

http://purl.obolibrary.org/obo/CHEBI_3084

http://purl.obolibrary.org/obo/dinto_DB01142

http://purl.obolibrary.org/obo/CHEBI_28177

http://purl.obolibrary.org/obo/CHEBI_8707

http://purl.obolibrary.org/obo/CHEBI_3183

http://purl.obolibrary.org/obo/CHEBI_47781

http://purl.obolibrary.org/obo/CHEBI_8382

http://purl.obolibrary.org/obo/dinto_DB00424

http://purl.obolibrary.org/obo/CHEBI_5118

http://purl.obolibrary.org/obo/CHEBI_5050

http://purl.obolibrary.org/obo/CHEBI_100241

http://purl.obolibrary.org/obo/CHEBI_6916

http://purl.obolibrary.org/obo/CHEBI_71418

http://purl.obolibrary.org/obo/dinto_DB01381

http://purl.obolibrary.org/obo/dinto_DB00462

http://purl.obolibrary.org/obo/dinto_DB00376

http://purl.obolibrary.org/obo/CHEBI_251408

http://purl.obolibrary.org/obo/CHEBI_4024

http://purl.obolibrary.org/obo/CHEBI_8461

http://purl.obolibrary.org/obo/CHEBI_15355

http://purl.obolibrary.org/obo/dinto_DB00986

http://purl.obolibrary.org/obo/CHEBI_18358

http://purl.obolibrary.org/obo/dinto_DB00934

http://purl.obolibrary.org/obo/dinto_DB01026

http://purl.obolibrary.org/obo/CHEBI_2666

http://purl.obolibrary.org/obo/CHEBI_3385

http://purl.obolibrary.org/obo/CHEBI_2950

http://purl.obolibrary.org/obo/CHEBI_6456

http://purl.obolibrary.org/obo/dinto_DB01380

http://purl.obolibrary.org/obo/CHEBI_9566

http://purl.obolibrary.org/obo/dinto_DB01114

http://purl.obolibrary.org/obo/CHEBI_5613

http://purl.obolibrary.org/obo/CHEBI_5818

http://purl.obolibrary.org/obo/CHEBI_8871

http://purl.obolibrary.org/obo/CHEBI_5138

http://purl.obolibrary.org/obo/dinto_DB01409

http://purl.obolibrary.org/obo/dinto_DB00752

http://purl.obolibrary.org/obo/CHEBI_3996

http://purl.obolibrary.org/obo/CHEBI_391960

http://purl.obolibrary.org/obo/CHEBI_100246

http://purl.obolibrary.org/obo/CHEBI_50885

http://purl.obolibrary.org/obo/dinto_DB01267

http://purl.obolibrary.org/obo/dinto_DB00780

http://purl.obolibrary.org/obo/CHEBI_3568

http://purl.obolibrary.org/obo/CHEBI_8448

http://purl.obolibrary.org/obo/CHEBI_7789

http://purl.obolibrary.org/obo/CHEBI_51364

http://purl.obolibrary.org/obo/CHEBI_3994

http://purl.obolibrary.org/obo/dinto_DB00782

http://purl.obolibrary.org/obo/dinto_DB00920

http://purl.obolibrary.org/obo/dinto_DB01085

http://purl.obolibrary.org/obo/dinto_DB01223

http://purl.obolibrary.org/obo/CHEBI_6780

http://purl.obolibrary.org/obo/CHEBI_8028

http://purl.obolibrary.org/obo/dinto_DB01122

http://purl.obolibrary.org/obo/CHEBI_3048

http://purl.obolibrary.org/obo/dinto_DB01303

http://purl.obolibrary.org/obo/CHEBI_4717

http://purl.obolibrary.org/obo/dinto_DB00209

http://purl.obolibrary.org/obo/CHEBI_5123

http://purl.obolibrary.org/obo/dinto_DB01110

http://purl.obolibrary.org/obo/CHEBI_45951

http://purl.obolibrary.org/obo/CHEBI_31236

http://purl.obolibrary.org/obo/CHEBI_41879

http://purl.obolibrary.org/obo/dinto_DB00980

http://purl.obolibrary.org/obo/CHEBI_16684

http://purl.obolibrary.org/obo/CHEBI_3398

http://purl.obolibrary.org/obo/CHEBI_5296

http://purl.obolibrary.org/obo/CHEBI_3766

http://purl.obolibrary.org/obo/CHEBI_8378

http://purl.obolibrary.org/obo/CHEBI_17650

http://purl.obolibrary.org/obo/CHEBI_4514

http://purl.obolibrary.org/obo/dinto_DB01171

http://purl.obolibrary.org/obo/dinto_DB00455

http://purl.obolibrary.org/obo/CHEBI_3647

http://purl.obolibrary.org/obo/dinto_DB00536

http://purl.obolibrary.org/obo/CHEBI_45652

http://purl.obolibrary.org/obo/dinto_DB04843

http://purl.obolibrary.org/obo/CHEBI_7735

http://purl.obolibrary.org/obo/CHEBI_47780

http://purl.obolibrary.org/obo/CHEBI_4636

http://purl.obolibrary.org/obo/CHEBI_50841

http://purl.obolibrary.org/obo/CHEBI_5088

http://purl.obolibrary.org/obo/CHEBI_2668

http://purl.obolibrary.org/obo/dinto_DB00726

http://purl.obolibrary.org/obo/dinto_DB01623

http://purl.obolibrary.org/obo/CHEBI_4046

http://purl.obolibrary.org/obo/CHEBI_3699

http://purl.obolibrary.org/obo/CHEBI_291342

http://purl.obolibrary.org/obo/CHEBI_16794

http://purl.obolibrary.org/obo/CHEBI_7565

http://purl.obolibrary.org/obo/CHEBI_2401

http://purl.obolibrary.org/obo/CHEBI_47381

http://purl.obolibrary.org/obo/dinto_DB00344

http://purl.obolibrary.org/obo/CHEBI_45979

http://purl.obolibrary.org/obo/CHEBI_3738

http://purl.obolibrary.org/obo/CHEBI_9622

http://purl.obolibrary.org/obo/CHEBI_2675

http://purl.obolibrary.org/obo/dinto_DB01591

http://purl.obolibrary.org/obo/CHEBI_8405

http://purl.obolibrary.org/obo/CHEBI_3112

http://purl.obolibrary.org/obo/CHEBI_10119

http://purl.obolibrary.org/obo/CHEBI_6888

http://purl.obolibrary.org/obo/CHEBI_50373

http://purl.obolibrary.org/obo/CHEBI_8435

http://purl.obolibrary.org/obo/dinto_DB00944

http://purl.obolibrary.org/obo/CHEBI_4604

http://purl.obolibrary.org/obo/CHEBI_46659

http://purl.obolibrary.org/obo/dinto_DB00540

http://purl.obolibrary.org/obo/CHEBI_7731

http://purl.obolibrary.org/obo/CHEBI_59269

http://purl.obolibrary.org/obo/dinto_DB01618

http://purl.obolibrary.org/obo/CHEBI_3743

http://purl.obolibrary.org/obo/CHEBI_5121

http://purl.obolibrary.org/obo/CHEBI_3077

http://purl.obolibrary.org/obo/dinto_DB00940

http://purl.obolibrary.org/obo/CHEBI_47499

http://purl.obolibrary.org/obo/dinto_DB01247

http://purl.obolibrary.org/obo/dinto_DB01246

http://purl.obolibrary.org/obo/CHEBI_27796

http://purl.obolibrary.org/obo/CHEBI_44915

prefixIRI

obo2:dinto_DB00382

prefLabel

tacrine

SMILES

NC1=C2CCCCC2=NC2=CC=CC=C12

Synonym

1,2,3,4-tetrahydroacridin-9-amine

C13H14N2

xref

National Drug Code Directory:59630-190-12

RxList:http://www.rxlist.com/cgi/generic2/tacrine.htm

Drugs.com:http://www.drugs.com/cdi/tacrine.html

ChEBI:9389

BindingDB:8961

Wikipedia:http://en.wikipedia.org/wiki/Tacrine

PubChem Compound:1935

PubChem Substance:46505487

ChemSpider:1859

PDB:760

PharmGKB:PA451576

subClassOf

http://purl.obolibrary.org/obo/dinto_000055

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Delete Mapping To Ontology Source
http://purl.bioontology.org/ontology/UATC/N06DA01 ATC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D013619 RH-MESH LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61961 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61961 NCIT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.494.046.250.900 RH-MESH LOOM
http://purl.bioontology.org/ontology/LNC/LP17860-5 LOINC LOOM
http://purl.jp/bio/4/id/200906021386422358 IOBC LOOM
http://doe-generated-ontology.com/OntoAD#C0039245 ONTOAD LOOM
http://purl.bioontology.org/ontology/NDDF/004378 NDDF LOOM
http://purl.bioontology.org/ontology/MESH/D013619 MESH LOOM
http://purl.bioontology.org/ontology/LNC/MTHU024717 LOINC LOOM
http://purl.bioontology.org/ontology/RXNORM/10318 RXNORM LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000021901 NDFRT LOOM
http://purl.obolibrary.org/obo/DRON_00012216 DRON LOOM
http://www.drugbank.ca/drugs/DB00382 FTC LOOM
http://scai.fraunhofer.de/AlzheimerOntology#Tacrine ADO LOOM
http://purl.obolibrary.org/obo/CHEBI_45980 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_45980 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_45980 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_45980 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_45980 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_45980 NIFSTD LOOM
http://stirdf.jst.go.jp/id/200907058721582459 IOBC LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/373727000 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/VANDF/4023896 VANDF LOOM