loading...| Preferred Name |
meprobamate |
|
| Synonyms |
2-[(carbamoyloxy)methyl]-2-methylpentyl carbamate C9H18N2O4 |
|
| ID |
http://purl.obolibrary.org/obo/dinto_DB00371 |
|
| activates |
http://purl.obolibrary.org/obo/dinto_0016 http://purl.obolibrary.org/obo/dinto_0630 http://purl.obolibrary.org/obo/dinto_2875 http://purl.obolibrary.org/obo/dinto_2778 |
|
| ATCCode |
N05BC01 |
|
| CASRN |
57-53-4 |
|
| DBBrand |
meprin tranmep mar-bate tranquiline milpath miltown mepantin ayermate hartol restinal trelmar robamate restran epicur aneurol equinil multaun meprospan anastress promato metranquil dicandiol meproban mepavlon epikur oasil reostral meprotanum ansil 3p bamate tranquilax enorden despasmol amepromat apasil miltamato erina shalvaton diurnal vio-bamate cypron orolevol tamate tranquillin klort meprosa diveron meprindon probamyl lepetown meprotil metractyl amosene meprodil pankalma trancot quietidon mepriam pancalma gadexyl tensol equilium perequietil mendel anathylmon estasil meprodiol tranquilate quanil nervonus calmax meptran misedant sedoselecta bamo 400 anxietil miltaun carbaxin anatimon dormabrol tranlisant miltann orlevol libiolan setran equazine-m neuramate mepronil artolon canquil 400 arcoban aneural meprovan harmonin tranquilsan quaname diron meprosin q-gesic auxietil deprol cyrpon canquil-400 calmiren appetrol-sr perquietil gagexyl restenil mepro-aspirin meproten tranquisan apo-meprobamate dapaz holbamate optarket sedoquil ataraxine larten equitar procalmidol trankvilan meprol morbam ipsotian mepro-analgesic biobamate andaksin meprobam cirpon nephentine andaxin perequil ayeramate meprocon cmc milprem anzil appetrol lepenil kessobamate protran scolazil kesso-bamate micrainin urbilat sedabamate rastenil my-trans tranquil bamate stensolo sowell vistabamate spantran sedanyl equatrate quivet bamd 400 crestanil meprotabs probate panediol miltwon fas-cile 200 meproleaf promate selene ansiatan paxin tranquilan sedanil seril aneuxral anural ecuanil procalmadol restinil wardamate equanil mepamtin ansiowas placitate biobamat mepiosine mepranil meprotan placidon meposed arpon ansietan sadanyl madiol miltuan fas-cile edenal procalmadiol calmadin brobamate tranquinol tensonal cirponyl atraxin pertranquil pensive aneuxal urbil zirpon solevione anastress wyseals pathibamate quanane meprocon proquanil meprocompren meprobamat sedazil sk-bamate letyl restenyl meprozine neo-tran apascil aneusral meprosan margonil prequil probamato pimal coprobate pan-tranquil |
|
| DBSynonym |
meprobamatum [inn-latin] procarbamide meprobamato [italian] meprobamic acid meprobamato [inn-spanish] dea no. 2820 meprobamat [german] |
|
| Definition |
A carbamate with hypnotic, sedative, and some muscle relaxant properties, although in therapeutic doses reduction of anxiety rather than a direct effect may be responsible for muscle relaxation. Meprobamate has been reported to have anticonvulsant actions against petit mal seizures, but not against grand mal seizures (which may be exacerbated). It is used in the treatment of anxiety disorders, and also for the short-term management of insomnia but has largely been superseded by the benzodiazepines. (From Martindale, The Extra Pharmacopoeia, 30th ed, p603) Meprobamate is a controlled substance in the U.S. |
|
| has effect |
http://purl.obolibrary.org/obo/OAE_0000388 http://purl.obolibrary.org/obo/OAE_0000449 http://purl.obolibrary.org/obo/OAE_0000377 http://purl.obolibrary.org/obo/OAE_0000630 http://purl.obolibrary.org/obo/OAE_0000376 http://purl.obolibrary.org/obo/OAE_0000373 http://purl.obolibrary.org/obo/OAE_0000660 http://purl.obolibrary.org/obo/OAE_0000600 http://purl.obolibrary.org/obo/OAE_0000920 http://purl.obolibrary.org/obo/OAE_0000608 http://purl.obolibrary.org/obo/OAE_0000770 http://purl.obolibrary.org/obo/OAE_0000287 http://purl.obolibrary.org/obo/OAE_0000601 http://purl.obolibrary.org/obo/OAE_0000642 http://purl.obolibrary.org/obo/OAE_0000283 http://purl.obolibrary.org/obo/OAE_0000268 http://purl.obolibrary.org/obo/OAE_0000400 http://purl.obolibrary.org/obo/OAE_0000086 http://purl.obolibrary.org/obo/OAE_0000645 http://purl.obolibrary.org/obo/OAE_0000584 http://purl.obolibrary.org/obo/OAE_0001129 http://purl.obolibrary.org/obo/OAE_0000542 http://purl.obolibrary.org/obo/OAE_0000355 http://purl.obolibrary.org/obo/OAE_0000460 http://purl.obolibrary.org/obo/OAE_0000866 http://purl.obolibrary.org/obo/OAE_0000487 http://purl.obolibrary.org/obo/OAE_0001147 http://purl.obolibrary.org/obo/OAE_0000362 http://purl.obolibrary.org/obo/OAE_0001291 http://purl.obolibrary.org/obo/OAE_0000394 |
|
| has pharmacological target |
http://purl.obolibrary.org/obo/dinto_0016 http://purl.obolibrary.org/obo/dinto_0630 http://purl.obolibrary.org/obo/dinto_2875 http://purl.obolibrary.org/obo/dinto_2778 |
|
| InChI |
InChI=1S/C9H18N2O4/c1-3-4-9(2,5-14-7(10)12)6-15-8(11)13/h3-6H2,1-2H3,(H2,10,12)(H2,11,13) |
|
| InChIKey |
InChIKey=NPPQSCRMBWNHMW-UHFFFAOYSA-N |
|
| inhibits | ||
| is metabolised by | ||
| label |
meprobamate |
|
| prefixIRI |
obo2:dinto_DB00371 |
|
| prefLabel |
meprobamate |
|
| SMILES |
CCCC(C)(COC(N)=O)COC(N)=O |
|
| Synonym |
2-[(carbamoyloxy)methyl]-2-methylpentyl carbamate C9H18N2O4 |
|
| xref |
PharmGKB:PA450377 RxList:http://www.rxlist.com/cgi/generic2/meprobamate.htm Drugs Product Database (DPD):2238646 Wikipedia:http://en.wikipedia.org/wiki/Meprobamate ChemSpider:3924 PubChem Compound:4064 Drugs.com:http://www.drugs.com/cdi/meprobamate.html National Drug Code Directory:23155-128-03 PDRhealth:http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/mil1268.shtml PubChem Substance:46508142 |
|
| subClassOf |