The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Jump to:
loading...
Preferred Name

chlorambucil
Synonyms

C14H19Cl2NO2

4-{4-[bis(2-chloroethyl)amino]phenyl}butanoic acid
ID

http://purl.obolibrary.org/obo/dinto_DB00291
AHFScode

10:00.00
ATCCode

L01AA02
CASRN

305-03-3
DBBrand

leukeran tablets

elcoril

pepstatin

amboclorin

ambochlorin

ecloril

leukoran

linfolizin

leukeran

linfolysin

leukersan
DBSynonym

chloroambucil

chlocambucil

chloraminophen

phenylbutyric acid nitrogen mustard

chlorbutine

chlorobutine

chlorobutin

chlorbutin

chloraminophene
Definition

A nitrogen mustard alkylating agent used as antineoplastic agent for the treatment of various malignant and nonmalignant diseases. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
has effect

http://purl.obolibrary.org/obo/OAE_0000879

http://purl.obolibrary.org/obo/OAE_0000449

http://purl.obolibrary.org/obo/OAE_0001154

http://purl.obolibrary.org/obo/OAE_0000376

http://purl.obolibrary.org/obo/OAE_0000617

http://purl.obolibrary.org/obo/OAE_0000267

http://purl.obolibrary.org/obo/OAE_0001286

http://purl.obolibrary.org/obo/OAE_0000512

http://purl.obolibrary.org/obo/OAE_0000415

http://purl.obolibrary.org/obo/OAE_0000373

http://purl.obolibrary.org/obo/OAE_0000418

http://purl.obolibrary.org/obo/OAE_0001448

http://purl.obolibrary.org/obo/OAE_0000205

http://purl.obolibrary.org/obo/OAE_0000365

http://purl.obolibrary.org/obo/OAE_0000600

http://purl.obolibrary.org/obo/OAE_0000310

http://purl.obolibrary.org/obo/OAE_0001365

http://purl.obolibrary.org/obo/OAE_0001485

http://purl.obolibrary.org/obo/OAE_0000539

http://purl.obolibrary.org/obo/OAE_0001053

http://purl.obolibrary.org/obo/OAE_0000601

http://purl.obolibrary.org/obo/OAE_0001275

http://purl.obolibrary.org/obo/OAE_0000943

http://purl.obolibrary.org/obo/OAE_0001190

http://purl.obolibrary.org/obo/OAE_0001341

http://purl.obolibrary.org/obo/OAE_0000645

http://purl.obolibrary.org/obo/OAE_0000584

http://purl.obolibrary.org/obo/OAE_0001129

http://purl.obolibrary.org/obo/OAE_0000542

http://purl.obolibrary.org/obo/OAE_0000752

http://purl.obolibrary.org/obo/OAE_0000034

http://purl.obolibrary.org/obo/OAE_0000166

http://purl.obolibrary.org/obo/OAE_0000647

http://purl.obolibrary.org/obo/OAE_0000468

http://purl.obolibrary.org/obo/OAE_0001147

http://purl.obolibrary.org/obo/OAE_0001217

http://purl.obolibrary.org/obo/OAE_0000396

http://purl.obolibrary.org/obo/OAE_0000275

http://purl.obolibrary.org/obo/OAE_0000347

http://purl.obolibrary.org/obo/OAE_0000362

http://purl.obolibrary.org/obo/OAE_0000374

http://purl.obolibrary.org/obo/OAE_0000211

http://purl.obolibrary.org/obo/OAE_0001364

http://purl.obolibrary.org/obo/OAE_0000402
InChI

InChI=1S/C14H19Cl2NO2/c15-8-10-17(11-9-16)13-6-4-12(5-7-13)2-1-3-14(18)19/h4-7H,1-3,8-11H2,(H,18,19)
InChIKey

InChIKey=JCKYGMPEJWAADB-UHFFFAOYSA-N
is metabolised by

http://purl.obolibrary.org/obo/dinto_3307
label

chlorambucil
may interact with

http://purl.obolibrary.org/obo/dinto_DB00108

http://purl.obolibrary.org/obo/CHEBI_61049

http://purl.obolibrary.org/obo/CHEBI_47657

http://purl.obolibrary.org/obo/dinto_DB00072

http://purl.obolibrary.org/obo/dinto_DB00337

http://purl.obolibrary.org/obo/CHEBI_6402
prefixIRI

obo2:dinto_DB00291
prefLabel

chlorambucil
related with

http://purl.obolibrary.org/obo/dinto_2873

http://purl.obolibrary.org/obo/dinto_1987
SMILES

OC(=O)CCCC1=CC=C(C=C1)N(CCCl)CCCl
Synonym

C14H19Cl2NO2

4-{4-[bis(2-chloroethyl)amino]phenyl}butanoic acid
xref

Wikipedia:http://en.wikipedia.org/wiki/Chlorambucil

National Drug Code Directory:0173-0635-35

PubChem Substance:46506842

RxList:http://www.rxlist.com/cgi/generic2/leukeran.htm

Drugs.com:http://www.drugs.com/cdi/chlorambucil.html

PharmGKB:PA448926

ChEBI:28830

ChemSpider:2607

PubChem Compound:2708

Drugs Product Database (DPD):4626
subClassOf

http://purl.obolibrary.org/obo/dinto_000055
Add comment
Add proposal
Delete Subject Author Type Created
No notes to display
Create mapping

Delete Mapping To Ontology Source
http://purl.obolibrary.org/obo/CHEBI_28830 CHEBI LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.455.526.728.650.156 RH-MESH LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147072 NDFRT LOOM
http://purl.org/obo/owl/CHEBI#CHEBI_28830 NPO LOOM
http://purl.bioontology.org/ontology/RXNORM/2346 RXNORM LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000147072 ODAE LOOM
http://purl.jp/bio/4/id/200906064084533224 IOBC LOOM
http://www.co-ode.org/ontologies/galen#Chlorambucil GALEN LOOM
http://purl.obolibrary.org/obo/DRON_00014630 ODNAE LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D002699 RH-MESH LOOM
https://go.drugbank.com/drugs/DB00291 MDM LOOM
http://purl.bioontology.org/ontology/RCD/h13.. RCD LOOM
http://purl.bioontology.org/ontology/CSP/1371-8226 CRISP LOOM
http://purl.obolibrary.org/obo/MESH_D002699 BERO LOOM
http://purl.obolibrary.org/obo/OMIT_0004023 OMIT LOOM
http://www.gamuts.net/entity#chlorambucil GAMUTS LOOM
http://www.phoc.org.cn/pmo/class/PMO_00017028 PMAPP-PMO LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0008163 OCHV LOOM
http://purl.obolibrary.org/obo/NCIT_C362 BERO LOOM
http://stirdf.jst.go.jp/id/200907000907030237 IOBC LOOM
http://purl.bioontology.org/ontology/SNMI/C-78050 SNMI LOOM
http://purl.obolibrary.org/obo/CHEBI_28830 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_28830 FIDEO LOOM
http://purl.obolibrary.org/obo/CHEBI_28830 FB-CV LOOM
http://purl.obolibrary.org/obo/CHEBI_28830 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_28830 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_28830 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_28830 NIFSTD LOOM
http://purl.obolibrary.org/obo/CHEBI_28830 PECO LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C362 NCIT LOOM
http://purl.bioontology.org/ontology/ATC/L01AA02 ATC LOOM
http://purl.bioontology.org/ontology/VANDF/4018769 VANDF LOOM
http://purl.bioontology.org/ontology/MESH/D002699 MESH LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387249003 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000043113 PDQ LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#2812 OCHV LOOM