The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

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Preferred Name	temazepam
Synonyms	C16H13ClN2O2 7-chloro-3-hydroxy-1-methyl-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-2-one
ID	http://purl.obolibrary.org/obo/dinto_DB00231
AHFScode	28:24.08
ATCCode	N05CD07
CASRN	846-50-4
DBBrand	restoril perdorm signopam euipnos apo-temazepam cerepax euhypnos levanxene temaz remestan mabertin levanzene crisonar normison levanxol gelthix planum novo-temazepam
DBSynonym	methyloxazepam hydroxydiazepam oxydiazepam n-methyloxazepam
Definition	A benzodiazepine that acts as a gamma-aminobutyric acid modulator and anti-anxiety agent. [PubChem]
has effect	http://purl.obolibrary.org/obo/OAE_0000388 http://purl.obolibrary.org/obo/OAE_0000081 http://purl.obolibrary.org/obo/OAE_0000377 http://purl.obolibrary.org/obo/OAE_0001045 http://purl.obolibrary.org/obo/OAE_0001509 http://purl.obolibrary.org/obo/OAE_0000512 http://purl.obolibrary.org/obo/OAE_0000482 http://purl.obolibrary.org/obo/OAE_0000365 http://purl.obolibrary.org/obo/OAE_0000600 http://purl.obolibrary.org/obo/OAE_0000310 http://purl.obolibrary.org/obo/OAE_0000601 http://purl.obolibrary.org/obo/OAE_0000300 http://purl.obolibrary.org/obo/OAE_0000542 http://purl.obolibrary.org/obo/OAE_0000414 http://purl.obolibrary.org/obo/OAE_0000034 http://purl.obolibrary.org/obo/OAE_0000166 http://purl.obolibrary.org/obo/OAE_0000460 http://purl.obolibrary.org/obo/OAE_0000505 http://purl.obolibrary.org/obo/OAE_0000396 http://purl.obolibrary.org/obo/OAE_0000242
has pharmacological target	http://purl.obolibrary.org/obo/dinto_0016 http://purl.obolibrary.org/obo/dinto_0630 http://purl.obolibrary.org/obo/dinto_2875 http://purl.obolibrary.org/obo/dinto_0045 http://purl.obolibrary.org/obo/dinto_0043 http://purl.obolibrary.org/obo/dinto_0044 http://purl.obolibrary.org/obo/dinto_0111 http://purl.obolibrary.org/obo/dinto_0114 http://purl.obolibrary.org/obo/dinto_2853 http://purl.obolibrary.org/obo/dinto_1453 http://purl.obolibrary.org/obo/dinto_1457 http://purl.obolibrary.org/obo/dinto_2778 http://purl.obolibrary.org/obo/dinto_0109 http://purl.obolibrary.org/obo/dinto_0107 http://purl.obolibrary.org/obo/dinto_0199 http://purl.obolibrary.org/obo/dinto_0038 http://purl.obolibrary.org/obo/dinto_3062 http://purl.obolibrary.org/obo/dinto_1948 http://purl.obolibrary.org/obo/dinto_0159
InChI	InChI=1S/C16H13ClN2O2/c1-19-13-8-7-11(17)9-12(13)14(18-15(20)16(19)21)10-5-3-2-4-6-10/h2-9,15,20H,1H3
InChIKey	InChIKey=SEQDDYPDSLOBDC-UHFFFAOYSA-N
is metabolised by	http://purl.obolibrary.org/obo/dinto_2058 http://purl.obolibrary.org/obo/dinto_0291 http://purl.obolibrary.org/obo/dinto_0901 http://purl.obolibrary.org/obo/dinto_1221 http://purl.obolibrary.org/obo/dinto_0465
label	temazepam
may interact with	http://purl.obolibrary.org/obo/dinto_DB01223 http://purl.obolibrary.org/obo/dinto_DB01322 http://purl.obolibrary.org/obo/CHEBI_3766 http://purl.obolibrary.org/obo/dinto_DB00427 http://purl.obolibrary.org/obo/CHEBI_4728 http://purl.obolibrary.org/obo/CHEBI_28177
prefixIRI	obo2:dinto_DB00231
prefLabel	temazepam
related with	http://purl.obolibrary.org/obo/dinto_0016 http://purl.obolibrary.org/obo/dinto_0630 http://purl.obolibrary.org/obo/dinto_2875 http://purl.obolibrary.org/obo/dinto_0045 http://purl.obolibrary.org/obo/dinto_0043 http://purl.obolibrary.org/obo/dinto_0044 http://purl.obolibrary.org/obo/dinto_0111 http://purl.obolibrary.org/obo/dinto_0114 http://purl.obolibrary.org/obo/dinto_2745 http://purl.obolibrary.org/obo/dinto_2853 http://purl.obolibrary.org/obo/dinto_1453 http://purl.obolibrary.org/obo/dinto_1457 http://purl.obolibrary.org/obo/dinto_2778 http://purl.obolibrary.org/obo/dinto_0109 http://purl.obolibrary.org/obo/dinto_0107 http://purl.obolibrary.org/obo/dinto_0199 http://purl.obolibrary.org/obo/dinto_0038 http://purl.obolibrary.org/obo/dinto_3062 http://purl.obolibrary.org/obo/dinto_1948 http://purl.obolibrary.org/obo/dinto_0159
SMILES	CN1C2=C(C=C(Cl)C=C2)C(=NC(O)C1=O)C1=CC=CC=C1
Synonym	C16H13ClN2O2 7-chloro-3-hydroxy-1-methyl-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-2-one
xref	PharmGKB:PA451608 ChemSpider:5198 PDRhealth:http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/res1373.shtml RxList:http://www.rxlist.com/cgi/generic/temaz.htm Drugs.com:http://www.drugs.com/temazepam.html National Drug Code Directory:53489-648-07 Drugs Product Database (DPD):2244815 PubChem Substance:46506604 Wikipedia:http://en.wikipedia.org/wiki/Temazepam PubChem Compound:5391
subClassOf	http://purl.obolibrary.org/obo/dinto_000055

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Mapping To	Ontology	Source
http://purl.obolibrary.org/obo/CHEBI_9435	CHEBI	LOOM
http://purl.bioontology.org/ontology/LNC/LP14551-3	LOINC	LOOM
http://www.co-ode.org/ontologies/galen#Temazepam	GALEN	LOOM
http://purl.obolibrary.org/obo/CHEBI_9435	PDRO	LOOM
http://purl.obolibrary.org/obo/CHEBI_9435	FIDEO	LOOM
http://purl.obolibrary.org/obo/CHEBI_9435	BERO	LOOM
http://purl.obolibrary.org/obo/CHEBI_9435	DRON	LOOM
http://purl.obolibrary.org/obo/MESH_D013693	BERO	LOOM
https://go.drugbank.com/drugs/DB00231	MDM	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0039468	OCHV	LOOM
http://purl.obolibrary.org/obo/OMIT_0014550	OMIT	LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387300007	SNOMEDCT	LOOM
http://purl.bioontology.org/ontology/RCD/x02Ml	RCD	LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000146246	NDFRT	LOOM
http://purl.bioontology.org/ontology/SNMI/C-645B0	SNMI	LOOM
http://purl.bioontology.org/ontology/LNC/MTHU001573	LOINC	LOOM
http://purl.jp/bio/4/id/200906071433283717	IOBC	LOOM
http://purl.bioontology.org/ontology/ATC/N05CD07	ATC	LOOM
http://www.semanticweb.org/administrator/ontologies/2022/0/untitled-ontology-34#OWLClass9e5ffeb7_8a4b_4423_be3c_01ac0dddb3cf	WWECA	LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29488	NCIT	LOOM
http://www.phoc.org.cn/pmo/class/PMO_00017587	PMAPP-PMO	LOOM
http://www.drugbank.ca/drugs/DB00231	FTC	LOOM
http://purl.bioontology.org/ontology/RXNORM/10355	RXNORM	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#12081	OCHV	LOOM
http://purl.obolibrary.org/obo/NCIT_C29488	BERO	LOOM
http://stirdf.jst.go.jp/id/200907058081363003	IOBC	LOOM
http://purl.bioontology.org/ontology/VANDF/4017894	VANDF	LOOM
http://purl.bioontology.org/ontology/MESH/D013693	MESH	LOOM
http://scai.fraunhofer.de/AlzheimerOntology#Temazepam	ADO	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.438.079.080.070.880	RH-MESH	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D013693	RH-MESH	LOOM