The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
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Preferred Name

indinavir
Synonyms

(2S)-1-[(2S,4R)-4-benzyl-2-hydroxy-4-{[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]carbamoyl}butyl]-N-tert-butyl-4-(pyridin-3-ylmethyl)piperazine-2-carboxamide

C36H47N5O4
ID

http://purl.obolibrary.org/obo/dinto_DB00224
AHFScode

08:18.08.08
ATCCode

J05AE02
CASRN

150378-17-9
DBBrand

crixivan
DBSynonym

indinavir sulfate

compound j
Definition

A potent and specific HIV protease inhibitor that appears to have good oral bioavailability. [PubChem]
has effect

http://purl.obolibrary.org/obo/OAE_0000388

http://purl.obolibrary.org/obo/OAE_0000449

http://purl.obolibrary.org/obo/OAE_0000599

http://purl.obolibrary.org/obo/OAE_0000453

http://purl.obolibrary.org/obo/OAE_0001373

http://purl.obolibrary.org/obo/OAE_0000377

http://purl.obolibrary.org/obo/OAE_0000902

http://purl.obolibrary.org/obo/OAE_0000391

http://purl.obolibrary.org/obo/OAE_0000376

http://purl.obolibrary.org/obo/OAE_0000493

http://purl.obolibrary.org/obo/OAE_0000308

http://purl.obolibrary.org/obo/OAE_0000415

http://purl.obolibrary.org/obo/OAE_0000195

http://purl.obolibrary.org/obo/OAE_0000373

http://purl.obolibrary.org/obo/OAE_0000210

http://purl.obolibrary.org/obo/OAE_0000382

http://purl.obolibrary.org/obo/OAE_0001397

http://purl.obolibrary.org/obo/OAE_0000600

http://purl.obolibrary.org/obo/OAE_0000310

http://purl.obolibrary.org/obo/OAE_0001365

http://purl.obolibrary.org/obo/OAE_0000454

http://purl.obolibrary.org/obo/OAE_0001026

http://purl.obolibrary.org/obo/OAE_0001042

http://purl.obolibrary.org/obo/OAE_0000360

http://purl.obolibrary.org/obo/OAE_0000601

http://purl.obolibrary.org/obo/OAE_0001463

http://purl.obolibrary.org/obo/OAE_0000645

http://purl.obolibrary.org/obo/OAE_0000584

http://purl.obolibrary.org/obo/OAE_0000894

http://purl.obolibrary.org/obo/OAE_0000243

http://purl.obolibrary.org/obo/OAE_0000414

http://purl.obolibrary.org/obo/OAE_0000038

http://purl.obolibrary.org/obo/OAE_0000034

http://purl.obolibrary.org/obo/OAE_0002122

http://purl.obolibrary.org/obo/OAE_0000343

http://purl.obolibrary.org/obo/OAE_0000385

http://purl.obolibrary.org/obo/OAE_0000468

http://purl.obolibrary.org/obo/OAE_0001279

http://purl.obolibrary.org/obo/OAE_0000396

http://purl.obolibrary.org/obo/OAE_0000390

http://purl.obolibrary.org/obo/OAE_0000362

http://purl.obolibrary.org/obo/OAE_0000565

http://purl.obolibrary.org/obo/OAE_0000501

http://purl.obolibrary.org/obo/OAE_0000374

http://purl.obolibrary.org/obo/OAE_0000358

http://purl.obolibrary.org/obo/OAE_0001364

http://purl.obolibrary.org/obo/OAE_0000402
has pharmacological target

http://purl.obolibrary.org/obo/dinto_3326
InChI

InChI=1S/C36H47N5O4/c1-36(2,3)39-35(45)31-24-40(22-26-12-9-15-37-21-26)16-17-41(31)23-29(42)19-28(18-25-10-5-4-6-11-25)34(44)38-33-30-14-8-7-13-27(30)20-32(33)43/h4-15,21,28-29,31-33,42-43H,16-20,22-24H2,1-3H3,(H,38,44)(H,39,45)/t28-,29+,31+,32-,33+/m1/s1
InChIKey

InChIKey=CBVCZFGXHXORBI-PXQQMZJSSA-N
induces

http://purl.obolibrary.org/obo/dinto_1440
inhibits

http://purl.obolibrary.org/obo/dinto_1970

http://purl.obolibrary.org/obo/dinto_2058

http://purl.obolibrary.org/obo/dinto_2990

http://purl.obolibrary.org/obo/dinto_2993

http://purl.obolibrary.org/obo/dinto_3326

http://purl.obolibrary.org/obo/dinto_0291

http://purl.obolibrary.org/obo/dinto_2019

http://purl.obolibrary.org/obo/dinto_1987

http://purl.obolibrary.org/obo/dinto_0901

http://purl.obolibrary.org/obo/dinto_1440

http://purl.obolibrary.org/obo/dinto_2828

http://purl.obolibrary.org/obo/dinto_1956
is metabolised by

http://purl.obolibrary.org/obo/dinto_2990

http://purl.obolibrary.org/obo/dinto_0901

http://purl.obolibrary.org/obo/dinto_1956
is transported by

http://purl.obolibrary.org/obo/dinto_0887

http://purl.obolibrary.org/obo/dinto_1440
label

indinavir
may interact with

http://purl.obolibrary.org/obo/dinto_DB00906

http://purl.obolibrary.org/obo/dinto_DB00683

http://purl.obolibrary.org/obo/CHEBI_8212

http://purl.obolibrary.org/obo/CHEBI_119486

http://purl.obolibrary.org/obo/CHEBI_32250

http://purl.obolibrary.org/obo/CHEBI_9948

http://purl.obolibrary.org/obo/CHEBI_9943

http://purl.obolibrary.org/obo/dinto_DB00801

http://purl.obolibrary.org/obo/CHEBI_119573

http://purl.obolibrary.org/obo/CHEBI_4317

http://purl.obolibrary.org/obo/CHEBI_71940

http://purl.obolibrary.org/obo/CHEBI_68642

http://purl.obolibrary.org/obo/CHEBI_41774

http://purl.obolibrary.org/obo/dinto_DB00541

http://purl.obolibrary.org/obo/CHEBI_37924

http://purl.obolibrary.org/obo/dinto_DB00243

http://purl.obolibrary.org/obo/CHEBI_10127

http://purl.obolibrary.org/obo/CHEBI_4858

http://purl.obolibrary.org/obo/dinto_DB06207

http://purl.obolibrary.org/obo/CHEBI_4031

http://purl.obolibrary.org/obo/CHEBI_8871

http://purl.obolibrary.org/obo/CHEBI_61049

http://purl.obolibrary.org/obo/dinto_DB00726

http://purl.obolibrary.org/obo/CHEBI_3756

http://purl.obolibrary.org/obo/dinto_DB06287

http://purl.obolibrary.org/obo/dinto_DB00342

http://purl.obolibrary.org/obo/CHEBI_53766

http://purl.obolibrary.org/obo/CHEBI_3611

http://purl.obolibrary.org/obo/CHEBI_40303

http://purl.obolibrary.org/obo/dinto_DB01370

http://purl.obolibrary.org/obo/CHEBI_133809

http://purl.obolibrary.org/obo/CHEBI_31794

http://purl.obolibrary.org/obo/dinto_DB01323

http://purl.obolibrary.org/obo/dinto_DB00570

http://purl.obolibrary.org/obo/CHEBI_3761

http://purl.obolibrary.org/obo/CHEBI_63621

http://purl.obolibrary.org/obo/CHEBI_10125

http://purl.obolibrary.org/obo/CHEBI_9654

http://purl.obolibrary.org/obo/dinto_DB00582

http://purl.obolibrary.org/obo/dinto_DB01558

http://purl.obolibrary.org/obo/CHEBI_8768

http://purl.obolibrary.org/obo/CHEBI_2611

http://purl.obolibrary.org/obo/CHEBI_6375

http://purl.obolibrary.org/obo/CHEBI_75988

http://purl.obolibrary.org/obo/CHEBI_63637

http://purl.obolibrary.org/obo/dinto_DB08901

http://purl.obolibrary.org/obo/CHEBI_3387

http://purl.obolibrary.org/obo/CHEBI_3720

http://purl.obolibrary.org/obo/dinto_DB01588

http://purl.obolibrary.org/obo/CHEBI_39548

http://purl.obolibrary.org/obo/dinto_DB01378

http://purl.obolibrary.org/obo/CHEBI_3732

http://purl.obolibrary.org/obo/CHEBI_480999

http://purl.obolibrary.org/obo/CHEBI_9622

http://purl.obolibrary.org/obo/CHEBI_45367

http://purl.obolibrary.org/obo/CHEBI_9398

http://purl.obolibrary.org/obo/CHEBI_10033

http://purl.obolibrary.org/obo/CHEBI_32315

http://purl.obolibrary.org/obo/CHEBI_421707

http://purl.obolibrary.org/obo/dinto_DB01118

http://purl.obolibrary.org/obo/dinto_DB00126

http://purl.obolibrary.org/obo/CHEBI_9139

http://purl.obolibrary.org/obo/CHEBI_7915

http://purl.obolibrary.org/obo/CHEBI_4513

http://purl.obolibrary.org/obo/CHEBI_7772

http://purl.obolibrary.org/obo/dinto_DB01369

http://purl.obolibrary.org/obo/CHEBI_49575

http://purl.obolibrary.org/obo/dinto_DB00690

http://purl.obolibrary.org/obo/CHEBI_50275

http://purl.obolibrary.org/obo/CHEBI_63584

http://purl.obolibrary.org/obo/dinto_DB01373

http://purl.obolibrary.org/obo/dinto_DB01026

http://purl.obolibrary.org/obo/CHEBI_2896

http://purl.obolibrary.org/obo/CHEBI_119915

http://purl.obolibrary.org/obo/CHEBI_114785

http://purl.obolibrary.org/obo/CHEBI_28077

http://purl.obolibrary.org/obo/dinto_DB02703

http://purl.obolibrary.org/obo/dinto_DB01589

http://purl.obolibrary.org/obo/CHEBI_9674

http://purl.obolibrary.org/obo/CHEBI_71272

http://purl.obolibrary.org/obo/CHEBI_38940

http://purl.obolibrary.org/obo/CHEBI_64318

http://purl.obolibrary.org/obo/CHEBI_70735

http://purl.obolibrary.org/obo/CHEBI_46295

http://purl.obolibrary.org/obo/dinto_DB00976

http://purl.obolibrary.org/obo/CHEBI_4562
prefixIRI

obo2:dinto_DB00224
prefLabel

indinavir
SMILES

CC(C)(C)NC(=O)[C@@H]1CN(CC2=CN=CC=C2)CCN1C[C@@H](O)C[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H]1[C@H](O)CC2=CC=CC=C12
Synonym

(2S)-1-[(2S,4R)-4-benzyl-2-hydroxy-4-{[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]carbamoyl}butyl]-N-tert-butyl-4-(pyridin-3-ylmethyl)piperazine-2-carboxamide

C36H47N5O4
xref

PharmGKB:PA449977

Drugs Product Database (DPD):2229161

RxList:http://www.rxlist.com/cgi/generic2/indinav.htm

Drugs.com:http://www.drugs.com/cdi/indinavir.html

ChEBI:5898

PubChem Compound:5362440

National Drug Code Directory:0006-0570-62

Wikipedia:http://en.wikipedia.org/wiki/Indinavir

BindingDB:517

ChemSpider:4515036

PubChem Substance:46506442
subClassOf

http://purl.obolibrary.org/obo/dinto_000055
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http://purl.obolibrary.org/obo/CHEBI_44032 HOIP LOOM
http://purl.obolibrary.org/obo/CHEBI_44032 CHEBI LOOM
http://purl.bioontology.org/ontology/MESH/D019469 MESH LOOM
http://purl.bioontology.org/ontology/CSP/4009-0058 CRISP LOOM
http://purl.obolibrary.org/obo/NCIT_C66877 BERO LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000022031 NDFRT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.383.725.385 RH-MESH LOOM
http://www.co-ode.org/ontologies/galen#Indinavir GALEN LOOM
https://go.drugbank.com/drugs/DB00224 MDM LOOM
http://purl.bioontology.org/ontology/RCD/eiH.. RCD LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D019469 RH-MESH LOOM
http://stirdf.jst.go.jp/id/200907022489273458 IOBC LOOM
http://purl.jp/bio/4/id/200906083006589307 IOBC LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/372529006 SNOMEDCT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C66877 NCIT LOOM
http://www.phoc.org.cn/pmo/class/PMO_00018374 PMAPP-PMO LOOM
http://purl.obolibrary.org/obo/OMIT_0019512 OMIT LOOM
http://purl.bioontology.org/ontology/ATC/J05AE02 ATC LOOM
http://purl.obolibrary.org/obo/CHEBI_44032 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_44032 FIDEO LOOM
http://purl.obolibrary.org/obo/CHEBI_44032 INBANCIDO LOOM
http://purl.obolibrary.org/obo/CHEBI_44032 COVID-19 LOOM
http://purl.obolibrary.org/obo/CHEBI_44032 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_44032 HUPSON LOOM
http://purl.obolibrary.org/obo/CHEBI_44032 TXPO LOOM
http://purl.obolibrary.org/obo/CHEBI_44032 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_44032 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_44032 CIDO LOOM
http://purl.obolibrary.org/obo/CHEBI_44032 NIFSTD LOOM
http://purl.bioontology.org/ontology/NDDF/005733 NDDF LOOM
http://purl.bioontology.org/ontology/LNC/MTHU013846 LOINC LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#31851 OCHV LOOM
http://purl.bioontology.org/ontology/LNC/LP21311-3 LOINC LOOM
http://purl.obolibrary.org/obo/MESH_D019469 BERO LOOM
http://purl.bioontology.org/ontology/VANDF/4024026 VANDF LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0376637 OCHV LOOM
http://purl.bioontology.org/ontology/RXNORM/114289 RXNORM LOOM
http://purl.obolibrary.org/obo/DRON_00013621 INBANCIDO LOOM
http://purl.obolibrary.org/obo/DRON_00013621 CIDO LOOM