The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Preferred Name

cyanocobalamin

Synonyms

C63H89CoN14O14P

ID

http://purl.obolibrary.org/obo/dinto_DB00115

AHFScode

88:08.00

ATCCode

B03BB01

B03BA01

CASRN

68-19-9

DBBrand

vitabee 12

crystamine

berubigen

cyomin

rubivite

neuroforte-r

ruvite

berocca pn

primabalt

shovite

rubramin pc

cyanoject

bedoz

cobex

cobolin-m

vibal

depinar

DBSynonym

vitamin b12 complex

cyanocob(iii)alamin

vitamin b12

Definition

Cyanocobalamin (commonly known as Vitamin B12) is the most chemically complex of all the vitamins. Cyanocobalamin s structure is based on a corrin ring, which, although similar to the porphyrin ring found in heme, chlorophyll, and cytochrome, has two of the pyrrole rings directly bonded. The central metal ion is Co (cobalt). Cyanocobalamin cannot be made by plants or by animals, as the only type of organisms that have the enzymes required for the synthesis of cyanocobalamin are bacteria and archaea. Higher plants do not concentrate cyanocobalamin from the soil and so are a poor source of the substance as compared with animal tissues. Cyanocobalamin is naturally found in foods including meat (especially liver and shellfish), eggs, and milk products. [HMDB]

has effect

http://purl.obolibrary.org/obo/OAE_0000185

http://purl.obolibrary.org/obo/OAE_0000377

http://purl.obolibrary.org/obo/OAE_0001345

http://purl.obolibrary.org/obo/OAE_0000632

http://purl.obolibrary.org/obo/OAE_0000842

http://purl.obolibrary.org/obo/OAE_0000300

http://purl.obolibrary.org/obo/OAE_0000600

http://purl.obolibrary.org/obo/OAE_0000596

http://purl.obolibrary.org/obo/OAE_0000780

http://purl.obolibrary.org/obo/OAE_0000317

http://purl.obolibrary.org/obo/OAE_0000375

http://purl.obolibrary.org/obo/OAE_0000374

http://purl.obolibrary.org/obo/OAE_0000376

http://purl.obolibrary.org/obo/OAE_0000497

http://purl.obolibrary.org/obo/OAE_0000382

http://purl.obolibrary.org/obo/OAE_0000414

http://purl.obolibrary.org/obo/OAE_0000601

http://purl.obolibrary.org/obo/OAE_0000310

http://purl.obolibrary.org/obo/OAE_0000453

http://purl.obolibrary.org/obo/OAE_0000350

http://purl.obolibrary.org/obo/OAE_0000388

http://purl.obolibrary.org/obo/OAE_0000779

http://purl.obolibrary.org/obo/OAE_0000362

http://purl.obolibrary.org/obo/OAE_0000373

has pharmacological target

http://purl.obolibrary.org/obo/dinto_2845

http://purl.obolibrary.org/obo/dinto_2771

InChI

InChI=1S/C62H90N13O14P.CN.Co/c1-29-20-39-40(21-30(29)2)75(28-70-39)57-52(84)53(41(27-76)87-57)89-90(85,86)88-31(3)26-69-49(83)18-19-59(8)37(22-46(66)80)56-62(11)61(10,25-48(68)82)36(14-17-45(65)79)51(74-62)33(5)55-60(9,24-47(67)81)34(12-15-43(63)77)38(71-55)23-42-58(6,7)35(13-16-44(64)78)50(72-42)32(4)54(59)73-56;1-2;/h20-21,23,28,31,34-37,41,52-53,56-57,76,84H,12-19,22,24-27H2,1-11H3,(H15,63,64,65,66,67,68,69,71,72,73,74,77,78,79,80,81,82,83,85,86);;/q;;+1/p-1/t31-,34-,35-,36-,37+,41-,52-,53-,56-,57+,59-,60+,61+,62+;;/m1../s1

InChIKey

InChIKey=SEKGMJVHSBBHRD-WZHZPDAFSA-M

is metabolised by

http://purl.obolibrary.org/obo/dinto_0381

is transported by

http://purl.obolibrary.org/obo/dinto_3281

http://purl.obolibrary.org/obo/dinto_1590

http://purl.obolibrary.org/obo/dinto_2167

http://purl.obolibrary.org/obo/dinto_1715

http://purl.obolibrary.org/obo/dinto_1548

label

cyanocobalamin

prefixIRI

obo2:dinto_DB00115

prefLabel

cyanocobalamin

related with

http://purl.obolibrary.org/obo/dinto_3595

http://purl.obolibrary.org/obo/dinto_3587

http://purl.obolibrary.org/obo/dinto_2845

http://purl.obolibrary.org/obo/dinto_2780

http://purl.obolibrary.org/obo/dinto_1620

http://purl.obolibrary.org/obo/dinto_2771

SMILES

OC[C@H]1O[C@@H]([C@H](O)[C@@H]1OP(O)(=O)O[C@]([H])(C)CNC(=O)CC[C@]1(C)[C@@H](CC(=O)N)[C@@]2([H])N([Co]C#N)C1=C(C)/C1=N/C(=C\C3=N\C(=C(C)/C4=N[C@]2(C)[C@@](C)(CC(=O)N)[C@@H]4CCC(=O)N)\[C@@](C)(CC(=O)N)[C@@H]3CCC(=O)N)/C(C)(C)[C@@H]1CCC(=O)N)N1C=NC2=CC(C)=C(C)C=C12

Synonym

C63H89CoN14O14P

xref

Drugs.com:http://www.drugs.com/cdi/cyanocobalamin-b12.html

National Drug Code Directory:0270-0519-16

PubChem Substance:46509031

ChEBI:17439

PharmGKB:PA451892

Drugs Product Database (DPD):274186

PDB:CNC

PubChem Compound:44176380

Wikipedia:http://en.wikipedia.org/wiki/Cyanocobalamin

RxList:http://www.rxlist.com/cgi/generic/b12inj.htm

PDRhealth:http://www.pdrhealth.com/drug_info/nmdrugprofiles/nutsupdrugs/vit_0262.shtml

ChemSpider:4575342

subClassOf

http://purl.obolibrary.org/obo/dinto_000055

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http://purl.bioontology.org/ontology/SNOMEDCT/419382002 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/LNC/LP15262-6 LOINC LOOM
http://www.co-ode.org/ontologies/galen#Cyanocobalamin GALEN LOOM
http://purl.bioontology.org/ontology/VANDF/4021896 VANDF LOOM
http://purl.bioontology.org/ontology/UATC/B03BA01 ATC LOOM
http://purl.bioontology.org/ontology/VANDF/4017441 VANDF LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C64333 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C64333 NCIT LOOM
http://www.drugbank.ca/drugs/DB00115 FTC LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000040295 PDQ LOOM
http://purl.bioontology.org/ontology/LNC/LP32549-5 LOINC LOOM