loading...| Preferred Name |
bevacizumab |
|
| Synonyms |
|
|
| ID |
http://purl.obolibrary.org/obo/dinto_DB00112 |
|
| AHFScode |
10:00.00 |
|
| ATCCode |
L01XC07 |
|
| CASRN |
216974-75-3 |
|
| DBBrand |
avastin (genentech inc) avastin |
|
| DBSynonym |
r-435 antivegf avastin |
|
| Definition |
A recombinant humanized monoclonal IgG1 antibody that binds to and inhibits the biologic activity of human vascular endothelial growth factor (VEGF). Bevacizumab contains human framework regions and the complementarity-determining regions of a murine antibody that binds to VEGF. Bevacizumab is produced in a Chinese Hamster Ovary mammalian cell expression system in a nutrient medium containing the antibiotic gentamicin and has a molecular weight of approximately 149 kilodaltons. |
|
| has pharmacological target | ||
| label |
bevacizumab |
|
| may interact with | ||
| prefixIRI |
obo2:dinto_DB00112 |
|
| prefLabel |
bevacizumab |
|
| related with |
http://purl.obolibrary.org/obo/dinto_3109 http://purl.obolibrary.org/obo/dinto_3105 http://purl.obolibrary.org/obo/dinto_3106 http://purl.obolibrary.org/obo/dinto_3107 http://purl.obolibrary.org/obo/dinto_3078 http://purl.obolibrary.org/obo/dinto_3084 http://purl.obolibrary.org/obo/dinto_3112 http://purl.obolibrary.org/obo/dinto_3111 http://purl.obolibrary.org/obo/dinto_2763 |
|
| xref |
PharmGKB:PA130232992 Wikipedia:http://en.wikipedia.org/wiki/Bevacizumab Drugs.com:http://www.drugs.com/cdi/bevacizumab-solution.html RxList:http://www.rxlist.com/cgi/generic3/avastin.htm National Drug Code Directory:50242-060-01 Drugs Product Database (DPD):2270994 |
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| subClassOf |