The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Preferred Name

daclizumab

Synonyms
ID

http://purl.obolibrary.org/obo/dinto_DB00111

AHFScode

92:00.00

ATCCode

L04AC01

CASRN

152923-56-3

DBBrand

zenapax (hoffmann-la roche inc)

DBSynonym

anti-il-2

ig gamma-1 chain c region

humanized anticd25

Definition

Humanized IgG1 Mab that binds to the human interleukin-2 receptor (anti-Tac or anti-CD25). Daclizumab is a composite of human (90%) and murine (10%) antibody sequences. The human sequences were derived from the constant domains of human IgG1 and the variable framework regions of the Eu myeloma antibody. The murine sequences were derived from the complementarity-determining regions of a murine anti-Tac antibody.

has pharmacological target

http://purl.obolibrary.org/obo/dinto_3333

http://purl.obolibrary.org/obo/dinto_3339

label

daclizumab

may interact with

http://purl.obolibrary.org/obo/dinto_DB06372

http://purl.obolibrary.org/obo/dinto_DB00072

prefixIRI

obo2:dinto_DB00111

prefLabel

daclizumab

related with

http://purl.obolibrary.org/obo/dinto_3109

http://purl.obolibrary.org/obo/dinto_3105

http://purl.obolibrary.org/obo/dinto_3106

http://purl.obolibrary.org/obo/dinto_3107

http://purl.obolibrary.org/obo/dinto_3078

http://purl.obolibrary.org/obo/dinto_3084

http://purl.obolibrary.org/obo/dinto_3112

http://purl.obolibrary.org/obo/dinto_3111

http://purl.obolibrary.org/obo/dinto_3709

http://purl.obolibrary.org/obo/dinto_3333

http://purl.obolibrary.org/obo/dinto_3339

http://purl.obolibrary.org/obo/dinto_3466

xref

Wikipedia:http://en.wikipedia.org/wiki/Daclizumab

GenBank:J00228

Drugs Product Database (DPD):2241473

Drugs.com:http://www.drugs.com/cdi/daclizumab.html

PharmGKB:PA164764446

UniProtKB:P01857

RxList:http://www.rxlist.com/cgi/generic3/zenapax.htm

subClassOf

http://purl.obolibrary.org/obo/dinto_000055

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