The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Preferred Name

trastuzumab

ID

http://purl.obolibrary.org/obo/dinto_DB00072

ATCCode

L01XC03

CASRN

180288-69-1

DBBrand

herceptin

DBSynonym

anti her2

ig gamma-1 chain c region

Definition

A recombinant IgG1 kappa, humanized monoclonal antibody that selectively binds with high affinity in a cell-based assay (Kd = 5 nM) to the extracellular domain of the human epidermal growth factor receptor protein. Produced in CHO cell culture.*

has pharmacological target

http://purl.obolibrary.org/obo/dinto_0259

inhibits

http://purl.obolibrary.org/obo/dinto_3102

label

trastuzumab

may interact with

http://purl.obolibrary.org/obo/CHEBI_71417

http://purl.obolibrary.org/obo/dinto_DB01285

http://purl.obolibrary.org/obo/dinto_DB00005

http://purl.obolibrary.org/obo/CHEBI_50667

http://purl.obolibrary.org/obo/CHEBI_63599

http://purl.obolibrary.org/obo/CHEBI_31941

http://purl.obolibrary.org/obo/CHEBI_8382

http://purl.obolibrary.org/obo/CHEBI_63632

http://purl.obolibrary.org/obo/dinto_DB00054

http://purl.obolibrary.org/obo/CHEBI_9555

http://purl.obolibrary.org/obo/dinto_DB00065

http://purl.obolibrary.org/obo/CHEBI_49668

http://purl.obolibrary.org/obo/dinto_DB00928

http://purl.obolibrary.org/obo/CHEBI_71418

http://purl.obolibrary.org/obo/dinto_DB00552

http://purl.obolibrary.org/obo/CHEBI_47898

http://purl.obolibrary.org/obo/CHEBI_2948

http://purl.obolibrary.org/obo/CHEBI_480999

http://purl.obolibrary.org/obo/CHEBI_46345

http://purl.obolibrary.org/obo/CHEBI_4911

http://purl.obolibrary.org/obo/CHEBI_15367

http://purl.obolibrary.org/obo/dinto_DB01281

http://purl.obolibrary.org/obo/dinto_DB00276

http://purl.obolibrary.org/obo/dinto_DB00095

http://purl.obolibrary.org/obo/CHEBI_38940

http://purl.obolibrary.org/obo/dinto_DB00694

http://purl.obolibrary.org/obo/CHEBI_114785

http://purl.obolibrary.org/obo/dinto_DB00051

http://purl.obolibrary.org/obo/CHEBI_4305

http://purl.obolibrary.org/obo/dinto_DB00888

http://purl.obolibrary.org/obo/dinto_DB01380

http://purl.obolibrary.org/obo/CHEBI_50729

http://purl.obolibrary.org/obo/dinto_DB00291

http://purl.obolibrary.org/obo/dinto_DB01206

http://purl.obolibrary.org/obo/CHEBI_31355

http://purl.obolibrary.org/obo/CHEBI_8764

http://purl.obolibrary.org/obo/dinto_DB00385

http://purl.obolibrary.org/obo/CHEBI_9513

http://purl.obolibrary.org/obo/CHEBI_175901

http://purl.obolibrary.org/obo/CHEBI_72564

http://purl.obolibrary.org/obo/CHEBI_4672

http://purl.obolibrary.org/obo/CHEBI_61049

http://purl.obolibrary.org/obo/dinto_DB00108

http://purl.obolibrary.org/obo/CHEBI_50885

http://purl.obolibrary.org/obo/dinto_DB00570

http://purl.obolibrary.org/obo/CHEBI_44185

http://purl.obolibrary.org/obo/CHEBI_681569

http://purl.obolibrary.org/obo/dinto_DB00026

http://purl.obolibrary.org/obo/dinto_DB01177

http://purl.obolibrary.org/obo/CHEBI_4027

http://purl.obolibrary.org/obo/dinto_DB00290

http://purl.obolibrary.org/obo/CHEBI_41879

http://purl.obolibrary.org/obo/dinto_DB00488

http://purl.obolibrary.org/obo/dinto_DB04572

http://purl.obolibrary.org/obo/CHEBI_28901

http://purl.obolibrary.org/obo/dinto_DB00023

http://purl.obolibrary.org/obo/dinto_DB00078

http://purl.obolibrary.org/obo/CHEBI_8378

http://purl.obolibrary.org/obo/CHEBI_17650

http://purl.obolibrary.org/obo/dinto_DB00075

http://purl.obolibrary.org/obo/dinto_DB00074

http://purl.obolibrary.org/obo/dinto_DB06287

http://purl.obolibrary.org/obo/CHEBI_63791

http://purl.obolibrary.org/obo/CHEBI_75988

http://purl.obolibrary.org/obo/dinto_DB00970

http://purl.obolibrary.org/obo/CHEBI_9288

http://purl.obolibrary.org/obo/dinto_DB00111

http://purl.obolibrary.org/obo/dinto_DB00087

http://purl.obolibrary.org/obo/CHEBI_52172

http://purl.obolibrary.org/obo/dinto_DB00305

http://purl.obolibrary.org/obo/dinto_DB00541

http://purl.obolibrary.org/obo/CHEBI_44423

http://purl.obolibrary.org/obo/CHEBI_45863

http://purl.obolibrary.org/obo/CHEBI_168396

http://purl.obolibrary.org/obo/CHEBI_63612

http://purl.obolibrary.org/obo/CHEBI_4031

http://purl.obolibrary.org/obo/dinto_DB00073

http://purl.obolibrary.org/obo/dinto_DB00997

http://purl.obolibrary.org/obo/dinto_DB00081

http://purl.obolibrary.org/obo/CHEBI_567361

http://purl.obolibrary.org/obo/CHEBI_4868

http://purl.obolibrary.org/obo/dinto_DB06372

http://purl.obolibrary.org/obo/CHEBI_5864

http://purl.obolibrary.org/obo/CHEBI_28876

http://purl.obolibrary.org/obo/CHEBI_6888

http://purl.obolibrary.org/obo/dinto_DB00762

http://purl.obolibrary.org/obo/CHEBI_50924

http://purl.obolibrary.org/obo/CHEBI_45783

http://purl.obolibrary.org/obo/CHEBI_60761

http://purl.obolibrary.org/obo/CHEBI_28680

http://purl.obolibrary.org/obo/CHEBI_3423

http://purl.obolibrary.org/obo/CHEBI_27899

http://purl.obolibrary.org/obo/dinto_DB00004

http://purl.obolibrary.org/obo/CHEBI_31348

http://purl.obolibrary.org/obo/dinto_DB00059

http://purl.obolibrary.org/obo/CHEBI_3077

http://purl.obolibrary.org/obo/CHEBI_9168

prefixIRI

obo2:dinto_DB00072

prefLabel

trastuzumab

related with

http://purl.obolibrary.org/obo/dinto_3466

http://purl.obolibrary.org/obo/dinto_3106

http://purl.obolibrary.org/obo/dinto_2792

http://purl.obolibrary.org/obo/dinto_3084

http://purl.obolibrary.org/obo/dinto_3105

http://purl.obolibrary.org/obo/dinto_3709

http://purl.obolibrary.org/obo/dinto_3111

http://purl.obolibrary.org/obo/dinto_3461

http://purl.obolibrary.org/obo/dinto_3109

http://purl.obolibrary.org/obo/dinto_0259

http://purl.obolibrary.org/obo/dinto_3107

http://purl.obolibrary.org/obo/dinto_3112

http://purl.obolibrary.org/obo/dinto_3078

xref

GenBank:J00228

Wikipedia:http://en.wikipedia.org/wiki/Trastuzumab

UniProtKB:P01857

National Drug Code Directory:50242-134-68

Drugs Product Database (DPD):2240692

Drugs.com:http://www.drugs.com/cdi/trastuzumab.html

RxList:http://www.rxlist.com/cgi/generic/trastuz.htm

PharmGKB:PA451743

subClassOf

http://purl.obolibrary.org/obo/dinto_000055

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http://purl.bioontology.org/ontology/MESH/D000068878 MESH LOOM
http://purl.bioontology.org/ontology/RXNORM/224905 RXNORM LOOM
http://bmi.utah.edu/ontologies/hfontology/C0728747 HFO LOOM
http://purl.bioontology.org/ontology/UATC/L01XC03 ATC LOOM
http://purl.bioontology.org/ontology/VANDF/4021140 VANDF LOOM
http://www.drugbank.ca/drugs/DB00072 FTC LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1647 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1647 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1647 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1647 NCIT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C112748 RH-MESH LOOM
http://purl.obolibrary.org/obo/DRON_00013025 ODNAE LOOM
http://purl.obolibrary.org/obo/DRON_00013025 DRON LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/327397006 SNOMEDCT LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000148593 ODAE LOOM
http://purl.jp/bio/4/id/200906019489166096 IOBC LOOM
http://d-nb.info/gnd/4661821-1 FAST-TOPICAL LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387003001 SNOMEDCT LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0004971 FASTO LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0004971 DDO LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0004971 DMTO LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000148593 NDFRT LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000042265 PDQ LOOM
http://data.bnf.fr/ark:/12148/cb14456492g FAST-TOPICAL LOOM