aldesleukin

http://purl.obolibrary.org/obo/dinto_DB00041

http://purl.obolibrary.org/obo/dinto_3083

http://purl.obolibrary.org/obo/dinto_3333

http://purl.obolibrary.org/obo/dinto_3339

10:00.00

L03AC01

85898-30-2

proleukin

proleukin (chiron corp)

t-cell growth factor

tcgf

il-2

interleukin-2 precursor

Aldesleukin, a lymphokine, is produced by recombinant DNA technology using a genetically engineered E. coli strain containing an analog of the human interleukin-2 gene. Genetic engineering techniques were used to modify the human IL-2 gene, and the resulting expression clone encodes a modified human interleukin-2. This recombinant form differs from native interleukin-2 in the following ways: a) Aldesleukin is not glycosylated because it is derived from E. coli; b) the molecule has no N-terminal alanine; the codon for this amino acid was deleted during the genetic engineering procedure; c) the molecule has serine substituted for cysteine at amino acid position 125.

http://purl.obolibrary.org/obo/dinto_3083

http://purl.obolibrary.org/obo/dinto_3333

http://purl.obolibrary.org/obo/dinto_3339

http://purl.obolibrary.org/obo/dinto_3611

http://purl.obolibrary.org/obo/dinto_3334

http://purl.obolibrary.org/obo/dinto_2116

http://purl.obolibrary.org/obo/dinto_0293

http://purl.obolibrary.org/obo/dinto_0901

aldesleukin

http://purl.obolibrary.org/obo/dinto_DB01285

http://purl.obolibrary.org/obo/CHEBI_205919

http://purl.obolibrary.org/obo/CHEBI_59582

http://purl.obolibrary.org/obo/dinto_3333

http://purl.obolibrary.org/obo/dinto_3339

obo2:dinto_DB00041

aldesleukin

PharmGKB:PA448081

National Drug Code Directory:0078-0495-61

UniProtKB:P60569

Wikipedia:http://en.wikipedia.org/wiki/Aldesleukin

Drugs Product Database (DPD):2130181

RxList:http://www.rxlist.com/cgi/generic2/aldesleukin.htm

GenBank:M11144

Drugs.com:http://www.drugs.com/cdi/aldesleukin.html

http://purl.obolibrary.org/obo/dinto_000055