The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Preferred Name

anakinra

Synonyms
ID

http://purl.obolibrary.org/obo/dinto_DB00026

AHFScode

92:00.00

ATCCode

L04AC03

blocks

http://purl.obolibrary.org/obo/dinto_3870

CASRN

143090-92-0

DBBrand

kineret (amgen inc)

DBSynonym

icil-1ra

il1 inhibitor

il-1ra

irap

interleukin-1 receptor antagonist protein precursor

il-1rn

Definition

Anakinra is a recombinant, nonglycosylated human interleukin-1 receptor antagonist (IL-1Ra). The difference between anakinra and the native human IL-1Ra is that anakinra has an extra methionine residue at the amino terminus. It is manufactured by using the E. coli expression system. Anakinra is composed of 153 amino acid residues. FDA approved on November 14, 2001.

has pharmacological target

http://purl.obolibrary.org/obo/dinto_3870

label

anakinra

may interact with

http://purl.obolibrary.org/obo/CHEBI_9513

http://purl.obolibrary.org/obo/dinto_DB06674

http://purl.obolibrary.org/obo/dinto_DB08904

http://purl.obolibrary.org/obo/dinto_DB06372

http://purl.obolibrary.org/obo/dinto_DB06168

http://purl.obolibrary.org/obo/dinto_DB00072

prefixIRI

obo2:dinto_DB00026

prefLabel

anakinra

xref

Drugs.com:http://www.drugs.com/cdi/anakinra.html

GenBank:M55646

Drugs Product Database (DPD):2245913

National Drug Code Directory:66658-234-28

PharmGKB:PA10799

RxList:http://www.rxlist.com/cgi/generic/anakinra.htm

Wikipedia:http://en.wikipedia.org/wiki/Anakinra

UniProtKB:P18510

subClassOf

http://purl.obolibrary.org/obo/dinto_000055

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