The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Preferred Name

etanercept

Synonyms
ID

http://purl.obolibrary.org/obo/dinto_DB00005

AHFScode

92:00.00

ATCCode

L04AB01

CASRN

185243-69-0

DBBrand

enbrel sureclick

enbrel

enbrel (immunex corp)

DBSynonym

tumor necrosis factor receptor 2

p75

cd120b

tumor necrosis factor receptor type ii

p80 tnf-alpha receptor

tnf-r2

tumor necrosis factor receptor superfamily member 1b precursor

Definition

Dimeric fusion protein consisting of the extracellular ligand-binding portion of the human 75 kilodalton (p75) tumor necrosis factor receptor (TNFR) linked to the Fc portion of human IgG1. The Fc component of etanercept contains the CH2 domain, the CH3 domain and hinge region, but not the CH1 domain of IgG1. Etanercept is produced by recombinant DNA technology in a Chinese hamster ovary (CHO) mammalian cell expression system. It consists of 934 amino acids

has pharmacological target

http://purl.obolibrary.org/obo/dinto_3490

inhibits

http://purl.obolibrary.org/obo/dinto_2116

label

etanercept

may interact with

http://purl.obolibrary.org/obo/dinto_DB06372

http://purl.obolibrary.org/obo/dinto_DB00072

prefixIRI

obo2:dinto_DB00005

prefLabel

etanercept

related with

http://purl.obolibrary.org/obo/dinto_3109

http://purl.obolibrary.org/obo/dinto_3105

http://purl.obolibrary.org/obo/dinto_3106

http://purl.obolibrary.org/obo/dinto_3107

http://purl.obolibrary.org/obo/dinto_3181

http://purl.obolibrary.org/obo/dinto_3078

http://purl.obolibrary.org/obo/dinto_3490

http://purl.obolibrary.org/obo/dinto_3084

http://purl.obolibrary.org/obo/dinto_3112

http://purl.obolibrary.org/obo/dinto_3111

http://purl.obolibrary.org/obo/dinto_0795

http://purl.obolibrary.org/obo/dinto_3709

http://purl.obolibrary.org/obo/dinto_3461

http://purl.obolibrary.org/obo/dinto_3466

xref

RxList:http://www.rxlist.com/cgi/generic/etanercept.htm

Drugs.com:http://www.drugs.com/cdi/etanercept.html

Drugs Product Database (DPD):2242903

National Drug Code Directory:58406-455-04

PharmGKB:PA449515

GenBank:M32315

UniProtKB:P20333

Wikipedia:http://en.wikipedia.org/wiki/Etanercept

subClassOf

http://purl.obolibrary.org/obo/dinto_000055

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Delete Mapping To Ontology Source
https://github.com/sap218/coid/blob/master/coid.owl#COID_00476 COID LOOM
http://purl.obolibrary.org/obo/NCIT_C2381 BERO LOOM
http://purl.bioontology.org/ontology/MESH/D000068800 MESH LOOM
http://www.drugbank.ca/drugs/DB00005 FTC LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000148590 NDFRT LOOM
http://purl.bioontology.org/ontology/LNC/LP220257-2 LOINC LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387045004 SNOMEDCT LOOM
http://www.phoc.org.cn/pmo/class/PMO_00022091 PMAPP-PMO LOOM
http://purl.bioontology.org/ontology/NDDF/007673 NDDF LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#45174 OCHV LOOM
http://purl.bioontology.org/ontology/RXNORM/214555 RXNORM LOOM
http://doe-generated-ontology.com/OntoAD#C0717758 ONTOAD LOOM
http://purl.bioontology.org/ontology/ATC/L04AB01 ATC LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000257809 PDQ LOOM
http://bmi.utah.edu/ontologies/hfontology/C0717758 HFO LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0717758 OCHV LOOM
https://go.drugbank.com/drugs/DB00005 MDM LOOM
http://purl.obolibrary.org/obo/MESH_D000068800 BERO LOOM
http://scai.fraunhofer.de/AlzheimerOntology#Etanercept ADO LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2381 NCIT LOOM
http://purl.bioontology.org/ontology/LNC/MTHU054569 LOINC LOOM
https://github.com/sap218/ocimido/blob/master/ontology/ocimido.owl#OCIMIDO_00023 OCIMIDO LOOM
http://purl.obolibrary.org/obo/CHEBI_4875 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_4875 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_4875 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_4875 CHEBI LOOM
http://bmi.utah.edu/ontologies/peontology/C0717758 RAO LOOM
http://purl.jp/bio/4/id/200906056230071693 IOBC LOOM
http://purl.bioontology.org/ontology/VANDF/4021136 VANDF LOOM
http://purl.obolibrary.org/obo/OMIT_0001329 OMIT LOOM