The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

Preferred Name	epidermal growth factor receptor
Synonyms	receptor tyrosine-protein kinase erbb-1
ID	http://purl.obolibrary.org/obo/dinto_2792
Definition	Isoform 2/truncated isoform may act as an antagonist
definition source	DrugBank Database
Gene	egfr
is blocked by	http://purl.obolibrary.org/obo/CHEBI_49668 http://purl.obolibrary.org/obo/CHEBI_49603 http://purl.obolibrary.org/obo/CHEBI_6456 http://purl.obolibrary.org/obo/CHEBI_114785 http://purl.obolibrary.org/obo/dinto_DB00002
is inhibited by	http://purl.obolibrary.org/obo/CHEBI_49960 http://purl.obolibrary.org/obo/CHEBI_61390 http://purl.obolibrary.org/obo/CHEBI_76003
is pharmacological target of	http://purl.obolibrary.org/obo/CHEBI_49668 http://purl.obolibrary.org/obo/dinto_DB01269 http://purl.obolibrary.org/obo/CHEBI_49603 http://purl.obolibrary.org/obo/CHEBI_61390 http://purl.obolibrary.org/obo/CHEBI_114785 http://purl.obolibrary.org/obo/dinto_DB00002 http://purl.obolibrary.org/obo/CHEBI_76003
label	epidermal growth factor receptor
OrganismClass	human
prefixIRI	obo2:dinto_2792
prefLabel	epidermal growth factor receptor
related with	http://purl.obolibrary.org/obo/dinto_DB01269 http://purl.obolibrary.org/obo/dinto_DB07602 http://purl.obolibrary.org/obo/dinto_DB03496 http://purl.obolibrary.org/obo/dinto_DB07662 http://purl.obolibrary.org/obo/dinto_DB00072
Synonym	receptor tyrosine-protein kinase erbb-1 epidermal growth factor receptor precursor ec 2.7.10.1
xref	DrugBank:844 UniProt ID:P00533
subClassOf	http://purl.obolibrary.org/obo/dinto_000128

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Mapping To	Ontology	Source
http://purl.obolibrary.org/obo/PR_000006933	EFO	LOOM
http://purl.obolibrary.org/obo/PR_000006933	GO-PLUS	LOOM
http://purl.obolibrary.org/obo/PR_000006933	OBA	LOOM
http://purl.obolibrary.org/obo/PR_000006933	EFO	LOOM
http://purl.obolibrary.org/obo/PR_000006933	PR	LOOM
http://purl.obolibrary.org/obo/PR_000006933	HUPSON	LOOM
http://purl.obolibrary.org/obo/PR_000006933	CIDO	LOOM
http://purl.obolibrary.org/obo/PR_000006933	NIFSTD	LOOM
http://scai.fraunhofer.de/CSEO#CSEO_00001103	CSEO	LOOM
http://www.drugtargetontology.org/dto/DTO_03100124	DTO	LOOM
http://bmi.utah.edu/ontologies/hfontology/C0034802	HFO	LOOM
http://purl.bioontology.org/ontology/LNC/MTHU004296	LOINC	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#10607	OCHV	LOOM
http://www.orpha.net/ORDO/Orphanet_121311	ORDO	LOOM
http://purl.uniprot.org/uniprot/P00533	FTC	LOOM
http://purl.bioontology.org/ontology/OMIM/131550	OMIM	LOOM
http://purl.obolibrary.org/obo/NCIT_C17068	BERO	LOOM
http://www.ncbi.nlm.nih.gov/gene/13649	NIFSTD	LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17068	NCIT	LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000042939	PDQ	LOOM
http://purl.bioontology.org/ontology/LNC/LP18396-9	LOINC	LOOM