The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Preferred Name

verapamil

Synonyms

C27H38N2O4

verapamil

2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile

verapamilo

Verapamil

verapamilum

ID

http://purl.obolibrary.org/obo/CHEBI_9948

AHFScode

24:28.92

ATCCode

C08DA01

CASRN

52-53-9

DBBrand

nu-verap

cardiagutt

isoptimo

calan

covera-hs

novo-veramil

drosteakard

securon

geangin

dignover

vasolan

verelan pm

veraptin

iproveratril

verexamil

isoptin sr

apo-verap

veramex

berkatens

dilacoran

veracim

cordilox

quasar

verelan

arpamyl

univer

calan sr

cardibeltin

isoptin

DBname

verapamil

DBSynonym

verapamilum [inn-latin]

verapamil [usan:ban:inn]

verapamilo [inn-spanish]

verapamil hcl

Definition

An L-type calcium channel blocker of the phenylalkylamine class.

has effect

http://purl.obolibrary.org/obo/OAE_0000081

http://purl.obolibrary.org/obo/OAE_0000505

http://purl.obolibrary.org/obo/OAE_0000400

http://purl.obolibrary.org/obo/OAE_0000770

http://purl.obolibrary.org/obo/OAE_0001068

http://purl.obolibrary.org/obo/OAE_0000401

http://purl.obolibrary.org/obo/OAE_0000377

http://purl.obolibrary.org/obo/OAE_0001345

http://purl.obolibrary.org/obo/OAE_0000677

http://purl.obolibrary.org/obo/OAE_0000567

http://purl.obolibrary.org/obo/OAE_0000207

http://purl.obolibrary.org/obo/OAE_0001509

http://purl.obolibrary.org/obo/OAE_0001001

http://purl.obolibrary.org/obo/OAE_0000449

http://purl.obolibrary.org/obo/OAE_0000333

http://purl.obolibrary.org/obo/OAE_0000391

http://purl.obolibrary.org/obo/OAE_0001025

http://purl.obolibrary.org/obo/OAE_0000600

http://purl.obolibrary.org/obo/OAE_0000242

http://purl.obolibrary.org/obo/OAE_0000534

http://purl.obolibrary.org/obo/OAE_0000385

http://purl.obolibrary.org/obo/OAE_0000406

http://purl.obolibrary.org/obo/OAE_0001373

http://purl.obolibrary.org/obo/OAE_0000468

http://purl.obolibrary.org/obo/OAE_0000811

http://purl.obolibrary.org/obo/OAE_0000375

http://purl.obolibrary.org/obo/OAE_0001468

http://purl.obolibrary.org/obo/OAE_0000374

http://purl.obolibrary.org/obo/OAE_0000630

http://purl.obolibrary.org/obo/OAE_0001297

http://purl.obolibrary.org/obo/OAE_0002206

http://purl.obolibrary.org/obo/OAE_0000539

http://purl.obolibrary.org/obo/OAE_0000343

http://purl.obolibrary.org/obo/OAE_0000785

http://purl.obolibrary.org/obo/OAE_0000319

http://purl.obolibrary.org/obo/OAE_0000376

http://purl.obolibrary.org/obo/OAE_0000487

http://purl.obolibrary.org/obo/OAE_0000921

http://purl.obolibrary.org/obo/OAE_0000382

http://purl.obolibrary.org/obo/OAE_0000358

http://purl.obolibrary.org/obo/OAE_0000565

http://purl.obolibrary.org/obo/OAE_0000460

http://purl.obolibrary.org/obo/OAE_0001069

http://purl.obolibrary.org/obo/OAE_0000034

http://purl.obolibrary.org/obo/OAE_0000021

http://purl.obolibrary.org/obo/OAE_0000415

http://purl.obolibrary.org/obo/OAE_0000601

http://purl.obolibrary.org/obo/OAE_0000310

http://purl.obolibrary.org/obo/OAE_0001370

http://purl.obolibrary.org/obo/OAE_0000645

http://purl.obolibrary.org/obo/OAE_0000453

http://purl.obolibrary.org/obo/OAE_0000038

http://purl.obolibrary.org/obo/OAE_0000350

http://purl.obolibrary.org/obo/OAE_0000166

http://purl.obolibrary.org/obo/OAE_0000602

http://purl.obolibrary.org/obo/OAE_0000210

http://purl.obolibrary.org/obo/OAE_0000388

http://purl.obolibrary.org/obo/OAE_0000584

http://purl.obolibrary.org/obo/OAE_0000779

http://purl.obolibrary.org/obo/OAE_0000362

http://purl.obolibrary.org/obo/OAE_0001309

http://purl.obolibrary.org/obo/OAE_0000607

http://purl.obolibrary.org/obo/OAE_0000373

has pharmacological target

http://purl.obolibrary.org/obo/dinto_1027

http://purl.obolibrary.org/obo/dinto_2965

http://purl.obolibrary.org/obo/dinto_2959

http://purl.obolibrary.org/obo/dinto_2975

http://purl.obolibrary.org/obo/dinto_1110

http://purl.obolibrary.org/obo/dinto_2979

http://purl.obolibrary.org/obo/dinto_2957

http://purl.obolibrary.org/obo/dinto_2962

has role

http://purl.obolibrary.org/obo/CHEBI_38215

http://purl.obolibrary.org/obo/CHEBI_38070

http://purl.obolibrary.org/obo/CHEBI_35620

InChI

InChI=1S/C27H38N2O4/c1-20(2)27(19-28,22-10-12-24(31-5)26(18-22)33-7)14-8-15-29(3)16-13-21-9-11-23(30-4)25(17-21)32-6/h9-12,17-18,20H,8,13-16H2,1-7H3

InChIKey

InChIKey=SGTNSNPWRIOYBX-UHFFFAOYSA-N

induces

http://purl.obolibrary.org/obo/dinto_1440

http://purl.obolibrary.org/obo/dinto_0465

inhibits

http://purl.obolibrary.org/obo/dinto_1973

http://purl.obolibrary.org/obo/dinto_1027

http://purl.obolibrary.org/obo/dinto_2019

http://purl.obolibrary.org/obo/dinto_2814

http://purl.obolibrary.org/obo/dinto_2058

http://purl.obolibrary.org/obo/dinto_2789

http://purl.obolibrary.org/obo/dinto_1956

http://purl.obolibrary.org/obo/dinto_2990

http://purl.obolibrary.org/obo/dinto_0901

http://purl.obolibrary.org/obo/dinto_0300

http://purl.obolibrary.org/obo/dinto_0931

http://purl.obolibrary.org/obo/dinto_0023

http://purl.obolibrary.org/obo/dinto_2828

http://purl.obolibrary.org/obo/dinto_0883

http://purl.obolibrary.org/obo/dinto_1987

http://purl.obolibrary.org/obo/dinto_2965

http://purl.obolibrary.org/obo/dinto_2959

http://purl.obolibrary.org/obo/dinto_3628

http://purl.obolibrary.org/obo/dinto_2993

http://purl.obolibrary.org/obo/dinto_0887

http://purl.obolibrary.org/obo/dinto_0588

http://purl.obolibrary.org/obo/dinto_1440

http://purl.obolibrary.org/obo/dinto_2975

http://purl.obolibrary.org/obo/dinto_1110

http://purl.obolibrary.org/obo/dinto_3489

http://purl.obolibrary.org/obo/dinto_2979

http://purl.obolibrary.org/obo/dinto_2957

http://purl.obolibrary.org/obo/dinto_3464

http://purl.obolibrary.org/obo/dinto_1970

http://purl.obolibrary.org/obo/dinto_3187

http://purl.obolibrary.org/obo/dinto_1540

http://purl.obolibrary.org/obo/dinto_2962

is metabolised by

http://purl.obolibrary.org/obo/dinto_2058

http://purl.obolibrary.org/obo/dinto_1956

http://purl.obolibrary.org/obo/dinto_2990

http://purl.obolibrary.org/obo/dinto_0901

http://purl.obolibrary.org/obo/dinto_0291

http://purl.obolibrary.org/obo/dinto_1959

http://purl.obolibrary.org/obo/dinto_0465

http://purl.obolibrary.org/obo/dinto_2651

http://purl.obolibrary.org/obo/dinto_1221

is transported by

http://purl.obolibrary.org/obo/dinto_1440

label

verapamil

may interact with

http://purl.obolibrary.org/obo/CHEBI_9073

http://purl.obolibrary.org/obo/CHEBI_3223

http://purl.obolibrary.org/obo/dinto_DB04855

http://purl.obolibrary.org/obo/dinto_DB00237

http://purl.obolibrary.org/obo/CHEBI_28177

http://purl.obolibrary.org/obo/dinto_DB01558

http://purl.obolibrary.org/obo/dinto_DB06212

http://purl.obolibrary.org/obo/CHEBI_64355

http://purl.obolibrary.org/obo/dinto_DB01396

http://purl.obolibrary.org/obo/dinto_DB00503

http://purl.obolibrary.org/obo/CHEBI_63621

http://purl.obolibrary.org/obo/dinto_DB00199

http://purl.obolibrary.org/obo/CHEBI_102166

http://purl.obolibrary.org/obo/CHEBI_31547

http://purl.obolibrary.org/obo/CHEBI_2379

http://purl.obolibrary.org/obo/CHEBI_63632

http://purl.obolibrary.org/obo/dinto_DB00224

http://purl.obolibrary.org/obo/CHEBI_3732

http://purl.obolibrary.org/obo/CHEBI_4551

http://purl.obolibrary.org/obo/dinto_DB01394

http://purl.obolibrary.org/obo/dinto_DB00312

http://purl.obolibrary.org/obo/CHEBI_68478

http://purl.obolibrary.org/obo/dinto_DB01601

http://purl.obolibrary.org/obo/CHEBI_37924

http://purl.obolibrary.org/obo/CHEBI_28077

http://purl.obolibrary.org/obo/dinto_DB00220

http://purl.obolibrary.org/obo/CHEBI_4856

http://purl.obolibrary.org/obo/dinto_DB00196

http://purl.obolibrary.org/obo/CHEBI_7494

http://purl.obolibrary.org/obo/CHEBI_32250

http://purl.obolibrary.org/obo/CHEBI_2636

http://purl.obolibrary.org/obo/dinto_DB00794

http://purl.obolibrary.org/obo/CHEBI_6758

http://purl.obolibrary.org/obo/dinto_DB01218

http://purl.obolibrary.org/obo/dinto_DB00243

http://purl.obolibrary.org/obo/dinto_DB01026

http://purl.obolibrary.org/obo/CHEBI_40050

http://purl.obolibrary.org/obo/dinto_DB01118

http://purl.obolibrary.org/obo/dinto_DB00976

http://purl.obolibrary.org/obo/dinto_DB00373

http://purl.obolibrary.org/obo/CHEBI_61049

http://purl.obolibrary.org/obo/dinto_DB01319

http://purl.obolibrary.org/obo/dinto_DB01167

http://purl.obolibrary.org/obo/CHEBI_70746

http://purl.obolibrary.org/obo/CHEBI_681850

http://purl.obolibrary.org/obo/dinto_DB01223

http://purl.obolibrary.org/obo/dinto_DB01369

http://purl.obolibrary.org/obo/dinto_DB01303

http://purl.obolibrary.org/obo/CHEBI_8364

http://purl.obolibrary.org/obo/CHEBI_6904

http://purl.obolibrary.org/obo/CHEBI_63628

http://purl.obolibrary.org/obo/dinto_DB01110

http://purl.obolibrary.org/obo/CHEBI_8499

http://purl.obolibrary.org/obo/dinto_DB01356

http://purl.obolibrary.org/obo/CHEBI_4681

http://purl.obolibrary.org/obo/CHEBI_3387

http://purl.obolibrary.org/obo/CHEBI_7444

http://purl.obolibrary.org/obo/CHEBI_102524

http://purl.obolibrary.org/obo/CHEBI_119573

http://purl.obolibrary.org/obo/CHEBI_45304

http://purl.obolibrary.org/obo/CHEBI_367163

http://purl.obolibrary.org/obo/CHEBI_9654

http://purl.obolibrary.org/obo/CHEBI_6343

http://purl.obolibrary.org/obo/CHEBI_28593

http://purl.obolibrary.org/obo/dinto_DB00342

http://purl.obolibrary.org/obo/CHEBI_39548

http://purl.obolibrary.org/obo/CHEBI_3127

http://purl.obolibrary.org/obo/CHEBI_40303

http://purl.obolibrary.org/obo/dinto_DB00622

http://purl.obolibrary.org/obo/CHEBI_3441

http://purl.obolibrary.org/obo/CHEBI_4031

http://purl.obolibrary.org/obo/dinto_DB01351

http://purl.obolibrary.org/obo/dinto_DB00073

http://purl.obolibrary.org/obo/CHEBI_45367

http://purl.obolibrary.org/obo/CHEBI_2904

http://purl.obolibrary.org/obo/CHEBI_9622

http://purl.obolibrary.org/obo/dinto_DB00683

http://purl.obolibrary.org/obo/dinto_DB01580

http://purl.obolibrary.org/obo/CHEBI_9150

http://purl.obolibrary.org/obo/dinto_DB00582

http://purl.obolibrary.org/obo/CHEBI_9674

http://purl.obolibrary.org/obo/CHEBI_68575

http://purl.obolibrary.org/obo/CHEBI_8069

http://purl.obolibrary.org/obo/CHEBI_45783

http://purl.obolibrary.org/obo/CHEBI_102216

http://purl.obolibrary.org/obo/CHEBI_8214

http://purl.obolibrary.org/obo/CHEBI_50861

http://purl.obolibrary.org/obo/CHEBI_9398

http://purl.obolibrary.org/obo/CHEBI_8107

http://purl.obolibrary.org/obo/dinto_DB06207

http://purl.obolibrary.org/obo/CHEBI_7447

http://purl.obolibrary.org/obo/dinto_DB00951

prefixIRI

obo2:CHEBI_9948

prefLabel

verapamil

related with

http://purl.obolibrary.org/obo/dinto_1670

http://purl.obolibrary.org/obo/dinto_2714

SMILES

COC1=C(OC)C=C(CCN(C)CCCC(C#N)(C(C)C)C2=CC(OC)=C(OC)C=C2)C=C1

COc1ccc(CCN(C)CCCC(C#N)(C(C)C)c2ccc(OC)c(OC)c2)cc1OC

Synonym

C27H38N2O4

verapamil

2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile

verapamilo

Verapamil

verapamilum

xref

ChEMBL:101219

ChemSpider:2425

BindingDB:50005628

PubChem Compound:2520

KEGG DRUG:D02356

Beilstein:2825000

ChEBI:9948

PubChem Substance:46508158

CASRN:52-53-9

Drugs.com:http://www.drugs.com/verapamil.html

PharmGKB:PA451868

IUPHAR:2406

Wikipedia:http://en.wikipedia.org/wiki/Verapamil

KEGG COMPOUND:C07188

DrugBank:DB00661

National Drug Code Directory:0091-4085-01

Drugs Product Database (DPD):2239769

Guide To Pharmacology:2406

RxList:http://www.rxlist.com/cgi/generic/verapsr.htm

subClassOf

http://purl.obolibrary.org/obo/dinto_000055

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Delete Mapping To Ontology Source
http://purl.bioontology.org/ontology/PDQ/CDR0000039730 PDQ LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.092.471.683.953 RH-MESH LOOM
http://d-nb.info/gnd/4062550-3 FAST-TOPICAL LOOM
http://purl.bioontology.org/ontology/NDDF/004515 NDDF LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D014700 RH-MESH LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/372754009 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/LNC/MTHU007771 LOINC LOOM
http://purl.jp/bio/4/id/200906047107040601 IOBC LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000148054 NDFRT LOOM
http://bmi.utah.edu/ontologies/hfontology/C0042523 HFO LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000148054 OCVDAE LOOM
http://www.drugbank.ca/drugs/DB00661 FTC LOOM
http://ontology.apa.org/apaonto/termsonlyOUT%20(5).owl#Verapamil APAONTO LOOM
http://purl.bioontology.org/ontology/SNMI/C-80490 SNMI LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C928 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C928 NCIT LOOM
http://stirdf.jst.go.jp/id/200907065943493604 IOBC LOOM
http://purl.obolibrary.org/obo/CHEBI_9948 PHIPO LOOM
http://purl.obolibrary.org/obo/CHEBI_9948 PHIPO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_9948 PHIPO LOOM
http://purl.obolibrary.org/obo/CHEBI_9948 PHIPO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_9948 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_9948 BIOMODELS SAME_URI
http://purl.obolibrary.org/obo/CHEBI_9948 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_9948 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_9948 CCONT LOOM
http://purl.obolibrary.org/obo/CHEBI_9948 CCONT SAME_URI
http://purl.obolibrary.org/obo/CHEBI_9948 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_9948 EFO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_9948 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_9948 DRON SAME_URI
http://purl.obolibrary.org/obo/CHEBI_9948 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_9948 EFO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_9948 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_9948 DRON SAME_URI
http://purl.obolibrary.org/obo/CHEBI_9948 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_9948 CHEBI SAME_URI
http://purl.bioontology.org/ontology/CSP/2268-7394 CRISP LOOM
http://doe-generated-ontology.com/OntoAD#C0042523 ONTOAD LOOM
http://purl.bioontology.org/ontology/MESH/D014700 MESH LOOM
http://purl.bioontology.org/ontology/RCD/x01QU RCD LOOM
http://stirdf.jst.go.jp/id/200907001651458621 IOBC LOOM
http://purl.jp/bio/4/id/200906076642470240 IOBC LOOM
http://purl.bioontology.org/ontology/RXNORM/11170 RXNORM LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#12957 OCHV LOOM
http://stirdf.jst.go.jp/id/200907009098573680 IOBC LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0042523 OCHV LOOM
http://purl.jp/bio/4/id/200906017005265599 IOBC LOOM
http://purl.bioontology.org/ontology/UATC/C08DA01 ATC LOOM
http://stirdf.jst.go.jp/id/200907073876348656 IOBC LOOM
http://mimi.case.edu/ontologies/2009/9/DrugOntology#verapamil SDO LOOM
http://purl.bioontology.org/ontology/VANDF/4019969 VANDF LOOM
http://purl.obolibrary.org/obo/XCO_0000616 XCO LOOM
http://purl.obolibrary.org/obo/XCO_0000616 XCO LOOM
http://www.gamuts.net/entity#verapamil GAMUTS LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0006181 FASTO LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0006181 DDO LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0006181 DMTO LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0006187 DDO LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0006187 DMTO LOOM
http://purl.bioontology.org/ontology/LNC/LP16307-8 LOINC LOOM
http://www.co-ode.org/ontologies/galen#Verapamil GALEN LOOM
http://purl.jp/bio/4/id/200906075738916960 IOBC LOOM
http://id.loc.gov/authorities/subjects/sh93000011 FAST-TOPICAL LOOM