The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Preferred Name

valsartan

Synonyms

valsartan

(S)-N-valeryl-N-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]-methyl}-valine

(2S)-3-methyl-2-[N-({4-[2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl}methyl)pentanamido]butanoic acid

N-pentanoyl-N-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-L-valine

N-pentanoyl-N-{[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}-L-valine

C24H29N5O3

Diovan

N-(p-(o-1H-tetrazol-5-ylphenyl)benzyl)-N-valeryl-L-valine

ID

http://purl.obolibrary.org/obo/CHEBI_9927

AHFScode

24:32.08

ATCCode

C09CA03

blocks

http://purl.obolibrary.org/obo/dinto_0968

CASRN

137862-53-4

DBBrand

diovan

valsarran

DBname

valsartan

Definition

A biphenylyltetrazole that has formula C24H29N5O3.

has effect

http://purl.obolibrary.org/obo/OAE_0000505

http://purl.obolibrary.org/obo/OAE_0000400

http://purl.obolibrary.org/obo/OAE_0000377

http://purl.obolibrary.org/obo/OAE_0000632

http://purl.obolibrary.org/obo/OAE_0000567

http://purl.obolibrary.org/obo/OAE_0001509

http://purl.obolibrary.org/obo/OAE_0000462

http://purl.obolibrary.org/obo/OAE_0000659

http://purl.obolibrary.org/obo/OAE_0000333

http://purl.obolibrary.org/obo/OAE_0000391

http://purl.obolibrary.org/obo/OAE_0001448

http://purl.obolibrary.org/obo/OAE_0001025

http://purl.obolibrary.org/obo/OAE_0000300

http://purl.obolibrary.org/obo/OAE_0001046

http://purl.obolibrary.org/obo/OAE_0000600

http://purl.obolibrary.org/obo/OAE_0000385

http://purl.obolibrary.org/obo/OAE_0000406

http://purl.obolibrary.org/obo/OAE_0000396

http://purl.obolibrary.org/obo/OAE_0001373

http://purl.obolibrary.org/obo/OAE_0000375

http://purl.obolibrary.org/obo/OAE_0001378

http://purl.obolibrary.org/obo/OAE_0000374

http://purl.obolibrary.org/obo/OAE_0002206

http://purl.obolibrary.org/obo/OAE_0001364

http://purl.obolibrary.org/obo/OAE_0000343

http://purl.obolibrary.org/obo/OAE_0000376

http://purl.obolibrary.org/obo/OAE_0001217

http://purl.obolibrary.org/obo/OAE_0000508

http://purl.obolibrary.org/obo/OAE_0000921

http://purl.obolibrary.org/obo/OAE_0000382

http://purl.obolibrary.org/obo/OAE_0000414

http://purl.obolibrary.org/obo/OAE_0000358

http://purl.obolibrary.org/obo/OAE_0000460

http://purl.obolibrary.org/obo/OAE_0000402

http://purl.obolibrary.org/obo/OAE_0000034

http://purl.obolibrary.org/obo/OAE_0000415

http://purl.obolibrary.org/obo/OAE_0000601

http://purl.obolibrary.org/obo/OAE_0000310

http://purl.obolibrary.org/obo/OAE_0000453

http://purl.obolibrary.org/obo/OAE_0000350

http://purl.obolibrary.org/obo/OAE_0000602

http://purl.obolibrary.org/obo/OAE_0000613

http://purl.obolibrary.org/obo/OAE_0000536

http://purl.obolibrary.org/obo/OAE_0000210

http://purl.obolibrary.org/obo/OAE_0000388

http://purl.obolibrary.org/obo/OAE_0000584

http://purl.obolibrary.org/obo/OAE_0000466

http://purl.obolibrary.org/obo/OAE_0000362

http://purl.obolibrary.org/obo/OAE_0001366

http://purl.obolibrary.org/obo/OAE_0000296

http://purl.obolibrary.org/obo/OAE_0000373

http://purl.obolibrary.org/obo/OAE_0000551

has pharmacological target

http://purl.obolibrary.org/obo/dinto_0968

has role

http://purl.obolibrary.org/obo/CHEBI_35674

http://purl.obolibrary.org/obo/CHEBI_61016

InChI

InChI=1S/C24H29N5O3/c1-4-5-10-21(30)29(22(16(2)3)24(31)32)15-17-11-13-18(14-12-17)19-8-6-7-9-20(19)23-25-27-28-26-23/h6-9,11-14,16,22H,4-5,10,15H2,1-3H3,(H,31,32)(H,25,26,27,28)/t22-/m0/s1

InChIKey

InChIKey=ACWBQPMHZXGDFX-QFIPXVFZSA-N

inhibits

http://purl.obolibrary.org/obo/dinto_2058

is metabolised by

http://purl.obolibrary.org/obo/dinto_2058

is transported by

http://purl.obolibrary.org/obo/dinto_2019

http://purl.obolibrary.org/obo/dinto_1824

label

valsartan

may interact with

http://purl.obolibrary.org/obo/dinto_DB00519

http://purl.obolibrary.org/obo/dinto_DB01345

http://purl.obolibrary.org/obo/dinto_DB06210

http://purl.obolibrary.org/obo/CHEBI_2636

http://purl.obolibrary.org/obo/dinto_DB00384

http://purl.obolibrary.org/obo/dinto_DB01356

http://purl.obolibrary.org/obo/CHEBI_2639

http://purl.obolibrary.org/obo/dinto_DB00073

http://purl.obolibrary.org/obo/dinto_DB00684

http://purl.obolibrary.org/obo/CHEBI_50861

prefixIRI

obo2:CHEBI_9927

prefLabel

valsartan

related with

http://purl.obolibrary.org/obo/dinto_0217

SMILES

CCCCC(=O)N(CC1=CC=C(C=C1)C1=CC=CC=C1C1=NNN=N1)[C@@H](C(C)C)C(O)=O

CCCCC(=O)N(Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1)[C@@H](C(C)C)C(O)=O

Synonym

valsartan

(S)-N-valeryl-N-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]-methyl}-valine

(2S)-3-methyl-2-[N-({4-[2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl}methyl)pentanamido]butanoic acid

N-pentanoyl-N-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-L-valine

N-pentanoyl-N-{[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}-L-valine

C24H29N5O3

Diovan

N-(p-(o-1H-tetrazol-5-ylphenyl)benzyl)-N-valeryl-L-valine

xref

ChEBI:9927

RxList:http://www.rxlist.com/cgi/generic/valsartan.htm

Drugs.com:http://www.drugs.com/cdi/valsartan.html

ChEMBL:239045

KEGG DRUG:D00400

PharmGKB:PA451848

PubChem Compound:60846

Patent:US5399578

Guide To Pharmacology:3937

National Drug Code Directory:0078-0360-34

Beilstein:7754038

DrugBank:DB00177

Drugs Product Database (DPD):2244781

Wikipedia:Valsartan

ChemSpider:54833

IUPHAR:3937

PubChem Substance:46509000

Patent:EP443983

Wikipedia:http://en.wikipedia.org/wiki/Valsartan

BindingDB:50049186

CASRN:137862-53-4

subClassOf

http://purl.obolibrary.org/obo/dinto_000055

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http://purl.bioontology.org/ontology/RXNORM/69749 RXNORM LOOM
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http://purl.obolibrary.org/obo/DRON_00017695 DRON LOOM
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http://purl.obolibrary.org/obo/CHEBI_9927 CHEBI LOOM
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http://purl.obolibrary.org/obo/CHEBI_9927 CHEBI LOOM
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http://purl.bioontology.org/ontology/PDQ/CDR0000464172 PDQ LOOM
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http://www.co-ode.org/ontologies/galen#Valsartan GALEN LOOM
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