The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

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Preferred Name	terazosin
Synonyms	6,7-dimethoxy-2-{4-[(oxolan-2-yl)carbonyl]piperazin-1-yl}quinazolin-4-amine terazosin terazosinum C19H25N5O4 terazosine 6,7-dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)piperazin-1-yl]quinazolin-4-amine terazosina Terazosine 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-((tetrahydro-2-furanyl)carbonyl)piperazine Terazosin
ID	http://purl.obolibrary.org/obo/CHEBI_9445
AHFScode	24:20.00
ATCCode	G04CA03
blocks	http://purl.obolibrary.org/obo/dinto_4020 http://purl.obolibrary.org/obo/dinto_3475 http://purl.obolibrary.org/obo/dinto_0234
CASRN	63590-64-7
DBBrand	urodie hytrinex vasomet flumarc blavin vicard fosfomic itrin hytracin heitrin hytrin
DBname	terazosin
DBSynonym	terazosine [inn-french] abbott 45975 terazosinum [inn-latin] terazosine terazosina [inn-spanish] terazosin hydrochloride trazosin hcl terazosin hcl
Definition	A piperazine that has formula C19H25N5O4.
has effect	http://purl.obolibrary.org/obo/OAE_0000388 http://purl.obolibrary.org/obo/OAE_0000447 http://purl.obolibrary.org/obo/OAE_0000453 http://purl.obolibrary.org/obo/OAE_0000604 http://purl.obolibrary.org/obo/OAE_0000377 http://purl.obolibrary.org/obo/OAE_0000902 http://purl.obolibrary.org/obo/OAE_0000391 http://purl.obolibrary.org/obo/OAE_0000335 http://purl.obolibrary.org/obo/OAE_0000479 http://purl.obolibrary.org/obo/OAE_0000659 http://purl.obolibrary.org/obo/OAE_0000596 http://purl.obolibrary.org/obo/OAE_0000406 http://purl.obolibrary.org/obo/OAE_0000561 http://purl.obolibrary.org/obo/OAE_0001509 http://purl.obolibrary.org/obo/OAE_0000411 http://purl.obolibrary.org/obo/OAE_0000443 http://purl.obolibrary.org/obo/OAE_0000921 http://purl.obolibrary.org/obo/OAE_0000308 http://purl.obolibrary.org/obo/OAE_0000567 http://purl.obolibrary.org/obo/OAE_0000373 http://purl.obolibrary.org/obo/OAE_0000319 http://purl.obolibrary.org/obo/OAE_0000412 http://purl.obolibrary.org/obo/OAE_0001448 http://purl.obolibrary.org/obo/OAE_0000660 http://purl.obolibrary.org/obo/OAE_0000382 http://purl.obolibrary.org/obo/OAE_0000677 http://purl.obolibrary.org/obo/OAE_0000600 http://purl.obolibrary.org/obo/OAE_0000310 http://purl.obolibrary.org/obo/OAE_0000426 http://purl.obolibrary.org/obo/OAE_0000601 http://purl.obolibrary.org/obo/OAE_0001463 http://purl.obolibrary.org/obo/OAE_0000375 http://purl.obolibrary.org/obo/OAE_0000300 http://purl.obolibrary.org/obo/OAE_0000551 http://purl.obolibrary.org/obo/OAE_0001062 http://purl.obolibrary.org/obo/OAE_0000498 http://purl.obolibrary.org/obo/OAE_0001515 http://purl.obolibrary.org/obo/OAE_0000400 http://purl.obolibrary.org/obo/OAE_0000584 http://purl.obolibrary.org/obo/OAE_0000842 http://purl.obolibrary.org/obo/OAE_0002206 http://purl.obolibrary.org/obo/OAE_0000414 http://purl.obolibrary.org/obo/OAE_0000607 http://purl.obolibrary.org/obo/OAE_0000355 http://purl.obolibrary.org/obo/OAE_0000789 http://purl.obolibrary.org/obo/OAE_0000968 http://purl.obolibrary.org/obo/OAE_0000034 http://purl.obolibrary.org/obo/OAE_0000166 http://purl.obolibrary.org/obo/OAE_0002122 http://purl.obolibrary.org/obo/OAE_0000460 http://purl.obolibrary.org/obo/OAE_0000508 http://purl.obolibrary.org/obo/OAE_0000401 http://purl.obolibrary.org/obo/OAE_0000343 http://purl.obolibrary.org/obo/OAE_0000536 http://purl.obolibrary.org/obo/OAE_0000505 http://purl.obolibrary.org/obo/OAE_0000385 http://purl.obolibrary.org/obo/OAE_0000468 http://purl.obolibrary.org/obo/OAE_0000602 http://purl.obolibrary.org/obo/OAE_0000779 http://purl.obolibrary.org/obo/OAE_0000396 http://purl.obolibrary.org/obo/OAE_0000390 http://purl.obolibrary.org/obo/OAE_0000362 http://purl.obolibrary.org/obo/OAE_0000374 http://purl.obolibrary.org/obo/OAE_0000462 http://purl.obolibrary.org/obo/OAE_0001309 http://purl.obolibrary.org/obo/OAE_0000534 http://purl.obolibrary.org/obo/OAE_0000402 http://purl.obolibrary.org/obo/OAE_0000350
has pharmacological target	http://purl.obolibrary.org/obo/dinto_4020 http://purl.obolibrary.org/obo/dinto_3475 http://purl.obolibrary.org/obo/dinto_0234
has role	http://purl.obolibrary.org/obo/CHEBI_35610 http://purl.obolibrary.org/obo/CHEBI_37890 http://purl.obolibrary.org/obo/CHEBI_35674
InChI	InChI=1S/C19H25N5O4/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14/h10-11,14H,3-9H2,1-2H3,(H2,20,21,22)
InChIKey	InChIKey=VCKUSRYTPJJLNI-UHFFFAOYSA-N
inhibits	http://purl.obolibrary.org/obo/dinto_0140 http://purl.obolibrary.org/obo/dinto_3187 http://purl.obolibrary.org/obo/dinto_1440 http://purl.obolibrary.org/obo/dinto_3483
label	terazosin
may interact with	http://purl.obolibrary.org/obo/CHEBI_8214 http://purl.obolibrary.org/obo/CHEBI_64022 http://purl.obolibrary.org/obo/CHEBI_71940 http://purl.obolibrary.org/obo/CHEBI_3437 http://purl.obolibrary.org/obo/CHEBI_8499 http://purl.obolibrary.org/obo/CHEBI_4856 http://purl.obolibrary.org/obo/dinto_DB06207 http://purl.obolibrary.org/obo/CHEBI_63622 http://purl.obolibrary.org/obo/CHEBI_3127 http://purl.obolibrary.org/obo/dinto_DB00373 http://purl.obolibrary.org/obo/CHEBI_3441 http://purl.obolibrary.org/obo/CHEBI_2904 http://purl.obolibrary.org/obo/dinto_DB01359 http://purl.obolibrary.org/obo/CHEBI_51141 http://purl.obolibrary.org/obo/CHEBI_6904 http://purl.obolibrary.org/obo/CHEBI_50861 http://purl.obolibrary.org/obo/CHEBI_9398 http://purl.obolibrary.org/obo/CHEBI_2379 http://purl.obolibrary.org/obo/dinto_DB00073 http://purl.obolibrary.org/obo/CHEBI_3082 http://purl.obolibrary.org/obo/dinto_DB01580 http://purl.obolibrary.org/obo/CHEBI_7444 http://purl.obolibrary.org/obo/CHEBI_9139 http://purl.obolibrary.org/obo/CHEBI_2636 http://purl.obolibrary.org/obo/CHEBI_6343 http://purl.obolibrary.org/obo/CHEBI_46295
prefixIRI	obo2:CHEBI_9445
prefLabel	terazosin
SMILES	COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)C1CCCO1 COC1=C(OC)C=C2C(N)=NC(=NC2=C1)N1CCN(CC1)C(=O)C1CCCO1
Synonym	6,7-dimethoxy-2-{4-[(oxolan-2-yl)carbonyl]piperazin-1-yl}quinazolin-4-amine terazosin terazosinum C19H25N5O4 terazosine 6,7-dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)piperazin-1-yl]quinazolin-4-amine terazosina Terazosine 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-((tetrahydro-2-furanyl)carbonyl)piperazine Terazosin
xref	RxList:http://www.rxlist.com/cgi/generic/teraz.htm KEGG COMPOUND:C07127 Wikipedia:Terazosin Drugs Product Database (DPD):2243749 Patent:US4026894 Patent:DE2831112 CASRN:63590-64-7 Wikipedia:http://en.wikipedia.org/wiki/Terazosin Beilstein:719452 National Drug Code Directory:0904-6126-61 ChEBI:9445 ChEMBL:123093 PubChem Substance:46509129 DrugBank:DB01162 ChemSpider:5208 PubChem Compound:5401 Patent:DE2646186 Drugs.com:http://www.drugs.com/terazosin.html PharmGKB:PA451612 Patent:US4251532
subClassOf	http://purl.obolibrary.org/obo/dinto_000055

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Mapping To	Ontology	Source
http://purl.obolibrary.org/obo/CHEBI_9445	CHEBI	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_9445	PDRO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_9445	BERO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_9445	BIOMODELS	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_9445	DRON	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_9445	NIFSTD	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_9445	CHEBI	LOOM
http://www.phoc.org.cn/pmo/class/PMO_00025809	PMAPP-PMO	LOOM
http://purl.bioontology.org/ontology/VANDF/4019940	VANDF	LOOM
https://go.drugbank.com/drugs/DB01162	MDM	LOOM
https://bioportal.bioontology.org/ontologies/STMSO#Terazosin	STMSO	LOOM
http://purl.bioontology.org/ontology/MESH/C041226	MESH	LOOM
http://purl.bioontology.org/ontology/RCD/x01CS	RCD	LOOM
http://purl.obolibrary.org/obo/CHEBI_9445	PDRO	LOOM
http://purl.obolibrary.org/obo/CHEBI_9445	BERO	LOOM
http://purl.obolibrary.org/obo/CHEBI_9445	BIOMODELS	LOOM
http://purl.obolibrary.org/obo/CHEBI_9445	DRON	LOOM
http://purl.obolibrary.org/obo/CHEBI_9445	NIFSTD	LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387068008	SNOMEDCT	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0076107	OCHV	LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000148025	OCVDAE	LOOM
http://purl.bioontology.org/ontology/NDDF/004492	NDDF	LOOM
http://purl.bioontology.org/ontology/LNC/LP101133-9	LOINC	LOOM
http://www.drugbank.ca/drugs/DB01162	FTC	LOOM
http://purl.bioontology.org/ontology/LNC/MTHU036183	LOINC	LOOM
http://purl.jp/bio/4/id/200906099100500488	IOBC	LOOM
http://purl.bioontology.org/ontology/ATC/G04CA03	ATC	LOOM
http://www.co-ode.org/ontologies/galen#Terazosin	GALEN	LOOM
http://purl.obolibrary.org/obo/NCIT_C61964	BERO	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C041226	RH-MESH	LOOM
http://purl.bioontology.org/ontology/RXNORM/37798	RXNORM	LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61964	NCIT	LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000148025	NDFRT	LOOM
http://stirdf.jst.go.jp/id/200907074301338426	IOBC	LOOM