The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Preferred Name

raloxifene

Synonyms

raloxifene

[6-hydroxy-2-(4-hydroxyphenyl)-1-benzothien-3-yl][4-(2-piperidin-1-ylethoxy)phenyl]methanone

LY 139481

C28H27NO4S

2-(4-hydroxyphenyl)-3-({4-[2-(piperidin-1-yl)ethoxy]phenyl}carbonyl)-1-benzothiophen-6-ol

(2-(4-Hydroxyphenyl)-6-hydroxybenzo(b)thien-3-yl)(4-(2-(1-piperidinyl)ethoxy)phenyl)methanone

raloxifeno

Raloxifene

raloxifenum

ID

http://purl.obolibrary.org/obo/CHEBI_8772

activates

http://purl.obolibrary.org/obo/dinto_2830

http://purl.obolibrary.org/obo/dinto_2827

AHFScode

68:16.12

ATCCode

G03XC01

CASRN

84449-90-1

DBBrand

keoxifene

evista

DBname

raloxifene

DBSynonym

raloxifene hcl

raloxifeno [spanish]

ly-139481

raloxifene hydrochloride

raloxifenum [latin]

ral

Definition

A benzothiophene that has formula C28H27NO4S.

has effect

http://purl.obolibrary.org/obo/OAE_0000400

http://purl.obolibrary.org/obo/OAE_0000401

http://purl.obolibrary.org/obo/OAE_0000185

http://purl.obolibrary.org/obo/OAE_0000377

http://purl.obolibrary.org/obo/OAE_0000632

http://purl.obolibrary.org/obo/OAE_0000567

http://purl.obolibrary.org/obo/OAE_0000462

http://purl.obolibrary.org/obo/OAE_0000496

http://purl.obolibrary.org/obo/OAE_0000600

http://purl.obolibrary.org/obo/OAE_0000534

http://purl.obolibrary.org/obo/OAE_0000385

http://purl.obolibrary.org/obo/OAE_0000406

http://purl.obolibrary.org/obo/OAE_0000050

http://purl.obolibrary.org/obo/OAE_0001340

http://purl.obolibrary.org/obo/OAE_0000766

http://purl.obolibrary.org/obo/OAE_0000596

http://purl.obolibrary.org/obo/OAE_0000502

http://purl.obolibrary.org/obo/OAE_0000501

http://purl.obolibrary.org/obo/OAE_0000317

http://purl.obolibrary.org/obo/OAE_0001263

http://purl.obolibrary.org/obo/OAE_0000375

http://purl.obolibrary.org/obo/OAE_0000711

http://purl.obolibrary.org/obo/OAE_0000479

http://purl.obolibrary.org/obo/OAE_0000374

http://purl.obolibrary.org/obo/OAE_0001744

http://purl.obolibrary.org/obo/OAE_0002206

http://purl.obolibrary.org/obo/OAE_0001515

http://purl.obolibrary.org/obo/OAE_0001505

http://purl.obolibrary.org/obo/OAE_0000861

http://purl.obolibrary.org/obo/OAE_0000343

http://purl.obolibrary.org/obo/OAE_0000319

http://purl.obolibrary.org/obo/OAE_0000084

http://purl.obolibrary.org/obo/OAE_0000460

http://purl.obolibrary.org/obo/OAE_0000402

http://purl.obolibrary.org/obo/OAE_0000021

http://purl.obolibrary.org/obo/OAE_0000601

http://purl.obolibrary.org/obo/OAE_0000453

http://purl.obolibrary.org/obo/OAE_0000647

http://purl.obolibrary.org/obo/OAE_0000498

http://purl.obolibrary.org/obo/OAE_0000350

http://purl.obolibrary.org/obo/OAE_0000536

http://purl.obolibrary.org/obo/OAE_0000514

http://purl.obolibrary.org/obo/OAE_0000561

http://purl.obolibrary.org/obo/OAE_0000455

http://purl.obolibrary.org/obo/OAE_0000362

has pharmacological target

http://purl.obolibrary.org/obo/dinto_2830

http://purl.obolibrary.org/obo/dinto_2827

has role

http://purl.obolibrary.org/obo/CHEBI_50739

http://purl.obolibrary.org/obo/CHEBI_50646

http://purl.obolibrary.org/obo/CHEBI_50837

InChI

InChI=1S/C28H27NO4S/c30-21-8-4-20(5-9-21)28-26(24-13-10-22(31)18-25(24)34-28)27(32)19-6-11-23(12-7-19)33-17-16-29-14-2-1-3-15-29/h4-13,18,30-31H,1-3,14-17H2

InChIKey

InChIKey=GZUITABIAKMVPG-UHFFFAOYSA-N

inhibits

http://purl.obolibrary.org/obo/dinto_0901

http://purl.obolibrary.org/obo/dinto_0273

http://purl.obolibrary.org/obo/dinto_0465

http://purl.obolibrary.org/obo/dinto_3102

http://purl.obolibrary.org/obo/dinto_1221

is metabolised by

http://purl.obolibrary.org/obo/dinto_0901

label

raloxifene

may interact with

http://purl.obolibrary.org/obo/CHEBI_3641

http://purl.obolibrary.org/obo/dinto_DB01432

http://purl.obolibrary.org/obo/dinto_DB00286

http://purl.obolibrary.org/obo/dinto_DB00783

http://purl.obolibrary.org/obo/dinto_DB00977

http://purl.obolibrary.org/obo/CHEBI_3752

http://purl.obolibrary.org/obo/CHEBI_41922

http://purl.obolibrary.org/obo/CHEBI_59594

http://purl.obolibrary.org/obo/dinto_DB04574

http://purl.obolibrary.org/obo/dinto_DB01357

http://purl.obolibrary.org/obo/CHEBI_18332

http://purl.obolibrary.org/obo/dinto_DB04573

http://purl.obolibrary.org/obo/CHEBI_59602

prefixIRI

obo2:CHEBI_8772

prefLabel

raloxifene

SMILES

Oc1ccc(cc1)-c1sc2cc(O)ccc2c1C(=O)c1ccc(OCCN2CCCCC2)cc1

OC1=CC=C(C=C1)C1=C(C(=O)C2=CC=C(OCCN3CCCCC3)C=C2)C2=C(S1)C=C(O)C=C2

Synonym

raloxifene

[6-hydroxy-2-(4-hydroxyphenyl)-1-benzothien-3-yl][4-(2-piperidin-1-ylethoxy)phenyl]methanone

LY 139481

C28H27NO4S

2-(4-hydroxyphenyl)-3-({4-[2-(piperidin-1-yl)ethoxy]phenyl}carbonyl)-1-benzothiophen-6-ol

(2-(4-Hydroxyphenyl)-6-hydroxybenzo(b)thien-3-yl)(4-(2-(1-piperidinyl)ethoxy)phenyl)methanone

raloxifeno

Raloxifene

raloxifenum

xref

RxList:http://www.rxlist.com/cgi/generic/raloxif.htm

PDRhealth:http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/evi1169.shtml

PharmGKB:PA451221

PubChem Substance:46506514

Guide To Pharmacology:2820

National Drug Code Directory:0002-4165-02

BindingDB:19441

KEGG COMPOUND:C07228

Drugs Product Database (DPD):2239028

Patent:US4418068

Drugs.com:http://www.drugs.com/cdi/raloxifene.html

Beilstein:4890356

ChEBI:8772

IUPHAR:2820

PDB:RAL

CASRN:84449-90-1

PubChem Compound:5035

DrugBank:DB00481

ChemSpider:4859

Wikipedia:http://en.wikipedia.org/wiki/Raloxifene

Patent:EP62503

subClassOf

http://purl.obolibrary.org/obo/dinto_000055

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http://www.co-ode.org/ontologies/galen#Raloxifene GALEN LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.455.426.559.389.150.700.900.775 RH-MESH LOOM
http://www.drugbank.ca/drugs/DB00481 FTC LOOM
http://purl.bioontology.org/ontology/UATC/G03XC01 ATC LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/419530003 SNOMEDCT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D020849 RH-MESH LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/109029006 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/VANDF/4024098 VANDF LOOM
http://purl.obolibrary.org/obo/CHEBI_8772 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_8772 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_8772 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_8772 EFO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_8772 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_8772 BIOMODELS SAME_URI
http://purl.obolibrary.org/obo/CHEBI_8772 CCONT LOOM
http://purl.obolibrary.org/obo/CHEBI_8772 CCONT SAME_URI
http://purl.obolibrary.org/obo/CHEBI_8772 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_8772 EFO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_8772 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_8772 EFO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_8772 NBO LOOM
http://purl.obolibrary.org/obo/CHEBI_8772 NBO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_8772 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_8772 EFO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_8772 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_8772 DRON SAME_URI
http://purl.obolibrary.org/obo/CHEBI_8772 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_8772 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_8772 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_8772 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_8772 NIFSTD LOOM
http://purl.obolibrary.org/obo/CHEBI_8772 NIFSTD SAME_URI
http://purl.bioontology.org/ontology/LNC/LP171633-3 LOINC LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000022103 NDFRT LOOM
http://stirdf.jst.go.jp/id/200907039651233937 IOBC LOOM
http://purl.bioontology.org/ontology/CSP/5001-0008 CRISP LOOM
http://purl.jp/bio/4/id/200906030196047290 IOBC LOOM
http://purl.jp/bio/4/id/200906030196047290 IOBC LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000043109 PDQ LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1518 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1518 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1518 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1518 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1518 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1518 NCIT LOOM
http://purl.bioontology.org/ontology/RXNORM/72143 RXNORM LOOM