The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Preferred Name

promethazine

Synonyms

(2-dimethylamino-2-methyl)ethyl-N-dibenzoparathiazine

promethazine

10-(2-Dimethylaminopropyl)phenothiazine

proazamine

promethazinum

N,N,alpha-trimethyl-10H-phenothiazine-10-ethanamine

dimethyl[1-(10H-phenothiazin-10-yl)propan-2-yl]amine

N-(2'-dimethylamino-2'-methyl)ethylphenothiazine

10-[2-(dimethylamino)propyl]phenothiazine

N,N-dimethyl-1-(10H-phenothiazin-10-yl)propan-2-amine

C17H20N2S

Promethazine

prometazina

ID

http://purl.obolibrary.org/obo/CHEBI_8461

AHFScode

04:04.12

ATCCode

D04AA10

R06AD02

R06AD05

blocks

http://purl.obolibrary.org/obo/dinto_3887

http://purl.obolibrary.org/obo/dinto_1071

http://purl.obolibrary.org/obo/dinto_0703

http://purl.obolibrary.org/obo/dinto_0392

http://purl.obolibrary.org/obo/dinto_1005

http://purl.obolibrary.org/obo/dinto_2097

http://purl.obolibrary.org/obo/dinto_3182

http://purl.obolibrary.org/obo/dinto_2804

CASRN

60-87-7

DBBrand

isophenergan

phencen

fargan

pyrethiazine

phenergan fortis

phenergan

vallergine

fellozine

iergigan

genphen

pipolphen

duplamin

fenetazina

lercigan

allergan

pyrethia

diprazine

phenargan

procit

dimapp

phargan

thiergan

promethacon

prorex

fenergan

avomine

protazine

romergan

diphergan

prometh plain

histargan

dorme

mymethazine fortis

prometh fortis

phensedyl

diprozin

remsed

prometasin

prometazin

lergigan

valergine

provigan

hiberna

tanidil

promethegan

fenazil

zipan-25

pilpophen

promethaine

aprobit

DBname

promethazine

DBSynonym

isopromethazine

prothazine

promazinamide

lilly 1516

proazamine

proazaimine

promethiazine

promethazine hcl

prometazine

promezathine

prothazin

promethazin

Definition

A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropan-2-amine moiety.

has effect

http://purl.obolibrary.org/obo/OAE_0000505

http://purl.obolibrary.org/obo/OAE_0000355

http://purl.obolibrary.org/obo/OAE_0000411

http://purl.obolibrary.org/obo/OAE_0000400

http://purl.obolibrary.org/obo/OAE_0000309

http://purl.obolibrary.org/obo/OAE_0000185

http://purl.obolibrary.org/obo/OAE_0000632

http://purl.obolibrary.org/obo/OAE_0000589

http://purl.obolibrary.org/obo/OAE_0000842

http://purl.obolibrary.org/obo/OAE_0000218

http://purl.obolibrary.org/obo/OAE_0001509

http://purl.obolibrary.org/obo/OAE_0001129

http://purl.obolibrary.org/obo/OAE_0000391

http://purl.obolibrary.org/obo/OAE_0001448

http://purl.obolibrary.org/obo/OAE_0000335

http://purl.obolibrary.org/obo/OAE_0001449

http://purl.obolibrary.org/obo/OAE_0000268

http://purl.obolibrary.org/obo/OAE_0000611

http://purl.obolibrary.org/obo/OAE_0000197

http://purl.obolibrary.org/obo/OAE_0000480

http://purl.obolibrary.org/obo/OAE_0000468

http://purl.obolibrary.org/obo/OAE_0000512

http://purl.obolibrary.org/obo/OAE_0000306

http://purl.obolibrary.org/obo/OAE_0002206

http://purl.obolibrary.org/obo/OAE_0000539

http://purl.obolibrary.org/obo/OAE_0001505

http://purl.obolibrary.org/obo/OAE_0000365

http://purl.obolibrary.org/obo/OAE_0000469

http://purl.obolibrary.org/obo/OAE_0000194

http://purl.obolibrary.org/obo/OAE_0000487

http://purl.obolibrary.org/obo/OAE_0000542

http://purl.obolibrary.org/obo/OAE_0000034

http://purl.obolibrary.org/obo/OAE_0000021

http://purl.obolibrary.org/obo/OAE_0000645

http://purl.obolibrary.org/obo/OAE_0000881

http://purl.obolibrary.org/obo/OAE_0001050

http://purl.obolibrary.org/obo/OAE_0000086

http://purl.obolibrary.org/obo/OAE_0000686

http://purl.obolibrary.org/obo/OAE_0000166

http://purl.obolibrary.org/obo/OAE_0000388

http://purl.obolibrary.org/obo/OAE_0001431

http://purl.obolibrary.org/obo/OAE_0000362

http://purl.obolibrary.org/obo/OAE_0000607

http://purl.obolibrary.org/obo/OAE_0000551

has pharmacological target

http://purl.obolibrary.org/obo/dinto_1071

has role

http://purl.obolibrary.org/obo/CHEBI_37955

http://purl.obolibrary.org/obo/CHEBI_36333

http://purl.obolibrary.org/obo/CHEBI_50919

http://purl.obolibrary.org/obo/CHEBI_50857

http://purl.obolibrary.org/obo/CHEBI_59683

http://purl.obolibrary.org/obo/CHEBI_35717

InChI

InChI=1S/C17H20N2S/c1-13(18(2)3)12-19-14-8-4-6-10-16(14)20-17-11-7-5-9-15(17)19/h4-11,13H,12H2,1-3H3

InChIKey

InChIKey=PWWVAXIEGOYWEE-UHFFFAOYSA-N

inhibits

http://purl.obolibrary.org/obo/dinto_2058

http://purl.obolibrary.org/obo/dinto_2993

http://purl.obolibrary.org/obo/dinto_1440

http://purl.obolibrary.org/obo/dinto_0753

is metabolised by

http://purl.obolibrary.org/obo/dinto_2993

http://purl.obolibrary.org/obo/dinto_0465

label

promethazine

may interact with

http://purl.obolibrary.org/obo/CHEBI_4530

http://purl.obolibrary.org/obo/dinto_DB00427

http://purl.obolibrary.org/obo/dinto_DB01578

http://purl.obolibrary.org/obo/CHEBI_439329

http://purl.obolibrary.org/obo/CHEBI_5280

http://purl.obolibrary.org/obo/dinto_DB01577

http://purl.obolibrary.org/obo/CHEBI_53289

http://purl.obolibrary.org/obo/dinto_DB01579

http://purl.obolibrary.org/obo/CHEBI_8080

http://purl.obolibrary.org/obo/CHEBI_9943

http://purl.obolibrary.org/obo/CHEBI_3044

http://purl.obolibrary.org/obo/CHEBI_32250

http://purl.obolibrary.org/obo/dinto_DB00752

http://purl.obolibrary.org/obo/dinto_DB00382

http://purl.obolibrary.org/obo/dinto_DB06700

http://purl.obolibrary.org/obo/dinto_DB01208

http://purl.obolibrary.org/obo/CHEBI_5557

http://purl.obolibrary.org/obo/CHEBI_5000

http://purl.obolibrary.org/obo/CHEBI_8067

http://purl.obolibrary.org/obo/dinto_DB00209

http://purl.obolibrary.org/obo/CHEBI_3720

http://purl.obolibrary.org/obo/dinto_DB04572

http://purl.obolibrary.org/obo/CHEBI_10124

http://purl.obolibrary.org/obo/dinto_DB00579

http://purl.obolibrary.org/obo/CHEBI_9654

http://purl.obolibrary.org/obo/dinto_DB00397

http://purl.obolibrary.org/obo/CHEBI_3181

http://purl.obolibrary.org/obo/dinto_DB00726

http://purl.obolibrary.org/obo/dinto_DB00342

http://purl.obolibrary.org/obo/dinto_DB00857

http://purl.obolibrary.org/obo/CHEBI_8874

http://purl.obolibrary.org/obo/dinto_DB00365

http://purl.obolibrary.org/obo/CHEBI_42944

http://purl.obolibrary.org/obo/CHEBI_63598

http://purl.obolibrary.org/obo/CHEBI_27796

http://purl.obolibrary.org/obo/CHEBI_2679

http://purl.obolibrary.org/obo/CHEBI_4469

prefixIRI

obo2:CHEBI_8461

prefLabel

promethazine

related with

http://purl.obolibrary.org/obo/dinto_0234

SMILES

CC(CN1C2=CC=CC=C2SC2=CC=CC=C12)N(C)C

CC(CN1c2ccccc2Sc2ccccc12)N(C)C

Synonym

(2-dimethylamino-2-methyl)ethyl-N-dibenzoparathiazine

promethazine

10-(2-Dimethylaminopropyl)phenothiazine

proazamine

promethazinum

N,N,alpha-trimethyl-10H-phenothiazine-10-ethanamine

dimethyl[1-(10H-phenothiazin-10-yl)propan-2-yl]amine

N-(2'-dimethylamino-2'-methyl)ethylphenothiazine

10-[2-(dimethylamino)propyl]phenothiazine

N,N-dimethyl-1-(10H-phenothiazin-10-yl)propan-2-amine

C17H20N2S

Promethazine

prometazina

xref

Drugs Product Database (DPD):583979

Reaxys:88554

ChEMBL:127368

DrugBank:DB01069

KEGG DRUG:D00494

ChEBI:8461

Beilstein:88554

ChemSpider:4758

NIST Chemistry WebBook:60-87-7

PubChem Substance:46507798

Drugs.com:http://www.drugs.com/promethazine.html

PubChem Compound:4927

KEGG COMPOUND:C07404

Wikipedia:http://en.wikipedia.org/wiki/Promethazine

Patent:US2530451

Patent:US2607773

RxList:http://www.rxlist.com/cgi/generic3/phenergan.htm

Wikipedia:Promethazine

PharmGKB:PA451128

Gmelin:337077

CASRN:60-87-7

National Drug Code Directory:0143-9869-22

subClassOf

http://purl.obolibrary.org/obo/dinto_000055

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http://purl.bioontology.org/ontology/UATC/D04AA10 ATC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.886.369.670 RH-MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D011398 RH-MESH LOOM
http://purl.jp/bio/4/id/200906006637143209 IOBC LOOM
http://www.co-ode.org/ontologies/galen#Promethazine GALEN LOOM
http://purl.bioontology.org/ontology/LNC/LP15006-7 LOINC LOOM
http://purl.obolibrary.org/obo/CHEBI_8461 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_8461 BIOMODELS SAME_URI
http://purl.obolibrary.org/obo/CHEBI_8461 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_8461 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_8461 CCONT LOOM
http://purl.obolibrary.org/obo/CHEBI_8461 CCONT SAME_URI
http://purl.obolibrary.org/obo/CHEBI_8461 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_8461 EFO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_8461 MCO LOOM
http://purl.obolibrary.org/obo/CHEBI_8461 MCO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_8461 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_8461 DRON SAME_URI
http://purl.obolibrary.org/obo/CHEBI_8461 NIFSTD LOOM
http://purl.obolibrary.org/obo/CHEBI_8461 NIFSTD SAME_URI
http://purl.bioontology.org/ontology/RCD/X79JO RCD LOOM
http://purl.bioontology.org/ontology/UATC/R06AD02 ATC LOOM
http://www.drugbank.ca/drugs/DB01069 FTC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.494.741.670 RH-MESH LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C779 NCIT LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0005754 FASTO LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0005754 DDO LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0005754 DMTO LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0005748 DDO LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0005748 DMTO LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147995 NDFRT LOOM
http://purl.bioontology.org/ontology/MESH/D011398 MESH LOOM
http://purl.bioontology.org/ontology/VANDF/4019910 VANDF LOOM
http://ontology.apa.org/apaonto/termsonlyOUT%20(5).owl#Promethazine APAONTO LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/372871004 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/SNMI/C-62820 SNMI LOOM
http://stirdf.jst.go.jp/id/200907048848800824 IOBC LOOM
http://purl.bioontology.org/ontology/LNC/MTHU001492 LOINC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.092.831.690 RH-MESH LOOM
http://purl.bioontology.org/ontology/RXNORM/8745 RXNORM LOOM
http://www.case.edu/EpSO.owl#Promethazine EPSO LOOM