loading...| Preferred Name |
trifluridine |
|
| Synonyms |
2'-deoxy-5-(trifluoromethyl)uridine 5-(Trifluoromethyl)deoxyuridine 5-Trifluoromethyl-2-deoxyuridine Trifluorothymidine 1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-(trifluoromethyl)-1,2,3,4-tetrahydropyrimidine-2,4-dione C10H11F3N2O5 trifluridinum trifluorothymine deoxyriboside Trifluoromethyldeoxyuridine Viroptic trifluridina trifluridine |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_75179 |
|
| AHFScode |
52:04.20 |
|
| altId |
CHEBI:9713 |
|
| ATCCode |
S01AD02 |
|
| CASRN |
70-00-8 |
|
| DBBrand |
trifluridine [usan:inn] f3tdr trifluridinum [inn-latin] f3t trifluridina [inn-spanish] f3dthd tfdu trifluorothymine deoxyriboside fluridine trifluorothymidine virophta viroptic trifluoromethyldeoxyuridine |
|
| DBname |
trifluridine |
|
| Definition |
A pyrimidine 2'-deoxyribonucleoside compound having 5-trifluoromethyluracil as the nucleobase. An antiviral drug used mainly in the treatment of primary keratoconjunctivitis and recurrent epithelial keratitis. |
|
| has effect | ||
| has pharmacological target | ||
| has role |
http://purl.obolibrary.org/obo/CHEBI_35610 http://purl.obolibrary.org/obo/CHEBI_63720 |
|
| InChI |
InChI=1S/C10H11F3N2O5/c11-10(12,13)4-2-15(9(19)14-8(4)18)7-1-5(17)6(3-16)20-7/h2,5-7,16-17H,1,3H2,(H,14,18,19)/t5-,6+,7+/m0/s1 |
|
| InChIKey |
InChIKey=VSQQQLOSPVPRAZ-RRKCRQDMSA-N |
|
| inhibits | ||
| is metabolised by | ||
| label |
trifluridine |
|
| prefixIRI |
obo2:CHEBI_75179 |
|
| prefLabel |
trifluridine |
|
| related with | ||
| SMILES |
OC[C@H]1O[C@H](C[C@@H]1O)N1C=C(C(=O)NC1=O)C(F)(F)F OC[C@H]1O[C@H](C[C@@H]1O)n1cc(c(=O)[nH]c1=O)C(F)(F)F |
|
| Synonym |
2'-deoxy-5-(trifluoromethyl)uridine 5-(Trifluoromethyl)deoxyuridine 5-Trifluoromethyl-2-deoxyuridine Trifluorothymidine 1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-(trifluoromethyl)-1,2,3,4-tetrahydropyrimidine-2,4-dione C10H11F3N2O5 trifluridinum trifluorothymine deoxyriboside Trifluoromethyldeoxyuridine Viroptic trifluridina trifluridine |
|
| xref |
PubChem Substance:46506192 CiteXplore:22735906 CiteXplore:22977515 National Drug Code Directory:61570-037-75 CiteXplore:22076553 HMDB:HMDB14576 CiteXplore:22607463 CiteXplore:23343513 PharmGKB:PA451775 PubChem Compound:6256 Reaxys:568095 CiteXplore:21278209 BindingDB:50132298 CiteXplore:22662200 CiteXplore:19816940 KEGG DRUG:D00391 Wikipedia:Trifluridine CiteXplore:19886911 CiteXplore:23386782 CASRN:70-00-8 DrugBank:DB00432 CiteXplore:21491084 CiteXplore:23919755 ChemSpider:6020 CiteXplore:23521072 CiteXplore:20861476 Wikipedia:http://en.wikipedia.org/wiki/Trifluridine ChEMBL:269321 Drugs Product Database (DPD):2248529 |
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| subClassOf |