The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Preferred Name

lorcaserin

Synonyms

C11H14ClN

(1R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine

lorcaserin

ID

http://purl.obolibrary.org/obo/CHEBI_65353

CASRN

846589-98-8

DBBrand

belviq

DBSalt

lorcaserin hydrochloride

DBSynonym

apd356

apd-356

Definition

Lorcaserin (previously APD-356), a highly selective 5HT2C receptor agonist, is used for the treatment of obesity. It has been shown to reduce body weight and food intake in animal models of obesity, and it is thought that targeting the 5HT2C receptor may alter body weight by regulating satiety. Lorcaserin is marketed as a salt form called Belviq, which is lorcaserin hydrochloride.

A benzazepine that is 2,3,4,5-tetrahydro-3-benzazepine substituted at position 1 by a methyl group and a t position 6 by a chloro group.

has role

http://purl.obolibrary.org/obo/CHEBI_50507

http://purl.obolibrary.org/obo/CHEBI_74518

InChI

InChI=1S/C11H14ClN/c1-8-7-13-5-4-9-2-3-10(12)6-11(8)9/h2-3,6,8,13H,4-5,7H2,1H3/t8-/m0/s1

InChIKey

InChIKey=XTTZERNUQAFMOF-QMMMGPOBSA-N

is metabolised by

http://purl.obolibrary.org/obo/dinto_2651

http://purl.obolibrary.org/obo/dinto_2993

http://purl.obolibrary.org/obo/dinto_0291

http://purl.obolibrary.org/obo/dinto_0269

http://purl.obolibrary.org/obo/dinto_0901

http://purl.obolibrary.org/obo/dinto_2496

http://purl.obolibrary.org/obo/dinto_0465

http://purl.obolibrary.org/obo/dinto_2045

label

lorcaserin

may interact with

http://purl.obolibrary.org/obo/CHEBI_9566

http://purl.obolibrary.org/obo/CHEBI_64318

prefixIRI

obo2:CHEBI_65353

prefLabel

lorcaserin

related with

http://purl.obolibrary.org/obo/dinto_0510

SMILES

C[C@H]1CNCCc2ccc(Cl)cc12

Synonym

C11H14ClN

(1R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine

lorcaserin

xref

ChEBI:65350

ChEMBL:401194

Wikipedia:http://en.wikipedia.org/wiki/Lorcaserin

Reaxys:9904422

Drugs.com:http://www.drugs.com/mtm/lorcaserin.html

CASRN:616202-92-7

RxList:http://www.rxlist.com/belviq-drug.htm

subClassOf

http://purl.obolibrary.org/obo/dinto_000055

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