Preferred Name |
lorcaserin |
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Synonyms |
C11H14ClN (1R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine lorcaserin |
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ID |
http://purl.obolibrary.org/obo/CHEBI_65353 |
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CASRN |
846589-98-8 |
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DBBrand |
belviq |
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DBSalt |
lorcaserin hydrochloride |
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DBSynonym |
apd356 apd-356 |
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Definition |
Lorcaserin (previously APD-356), a highly selective 5HT2C receptor agonist, is used for the treatment of obesity. It has been shown to reduce body weight and food intake in animal models of obesity, and it is thought that targeting the 5HT2C receptor may alter body weight by regulating satiety. Lorcaserin is marketed as a salt form called Belviq, which is lorcaserin hydrochloride. A benzazepine that is 2,3,4,5-tetrahydro-3-benzazepine substituted at position 1 by a methyl group and a t position 6 by a chloro group. |
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has role | ||
InChI |
InChI=1S/C11H14ClN/c1-8-7-13-5-4-9-2-3-10(12)6-11(8)9/h2-3,6,8,13H,4-5,7H2,1H3/t8-/m0/s1 |
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InChIKey |
InChIKey=XTTZERNUQAFMOF-QMMMGPOBSA-N |
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is metabolised by |
http://purl.obolibrary.org/obo/dinto_2651 http://purl.obolibrary.org/obo/dinto_2993 http://purl.obolibrary.org/obo/dinto_0291 http://purl.obolibrary.org/obo/dinto_0269 http://purl.obolibrary.org/obo/dinto_0901 http://purl.obolibrary.org/obo/dinto_2496 |
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label |
lorcaserin |
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may interact with | ||
prefixIRI |
obo2:CHEBI_65353 |
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prefLabel |
lorcaserin |
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related with | ||
SMILES |
C[C@H]1CNCCc2ccc(Cl)cc12 |
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Synonym |
C11H14ClN (1R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine lorcaserin |
|
xref |
ChEBI:65350 ChEMBL:401194 Wikipedia:http://en.wikipedia.org/wiki/Lorcaserin Reaxys:9904422 Drugs.com:http://www.drugs.com/mtm/lorcaserin.html CASRN:616202-92-7 |
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subClassOf |