The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Preferred Name

tizanidine

Synonyms

tizanidine

C9H8ClN5S

tizanidina

5-Chloro-4-(2-imidazolin-2-ylamino)-2,1,3-benzothiadiazole

5-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-2,1,3-benzothiadiazol-4-amine

tizanidinum

Tizanidine

ID

http://purl.obolibrary.org/obo/CHEBI_63629

activates

http://purl.obolibrary.org/obo/dinto_1581

http://purl.obolibrary.org/obo/dinto_3877

http://purl.obolibrary.org/obo/dinto_0141

http://purl.obolibrary.org/obo/dinto_1135

AHFScode

12:20.00

altId

CHEBI:9608

ATCCode

M03BX02

CASRN

51322-75-9

DBBrand

sirdalud

ternelin

zanaflex

DBname

tizanidine

DBSynonym

tizanidina [inn-spanish]

tizanidinum [inn-latin]

tizanidine hcl

Definition

2,1,3-Benzothiadiazole substituted at C-4 by a Delta(1)-imidazolin-2-ylamino group and at C-4 by a chloro group. It is an agonist at alpha2-adrenergic receptor sites.

has effect

http://purl.obolibrary.org/obo/OAE_0000426

http://purl.obolibrary.org/obo/OAE_0000505

http://purl.obolibrary.org/obo/OAE_0000355

http://purl.obolibrary.org/obo/OAE_0000573

http://purl.obolibrary.org/obo/OAE_0000411

http://purl.obolibrary.org/obo/OAE_0000400

http://purl.obolibrary.org/obo/OAE_0000309

http://purl.obolibrary.org/obo/OAE_0000390

http://purl.obolibrary.org/obo/OAE_0000401

http://purl.obolibrary.org/obo/OAE_0000412

http://purl.obolibrary.org/obo/OAE_0001345

http://purl.obolibrary.org/obo/OAE_0000632

http://purl.obolibrary.org/obo/OAE_0000567

http://purl.obolibrary.org/obo/OAE_0000218

http://purl.obolibrary.org/obo/OAE_0001509

http://purl.obolibrary.org/obo/OAE_0000462

http://purl.obolibrary.org/obo/OAE_0000473

http://purl.obolibrary.org/obo/OAE_0001129

http://purl.obolibrary.org/obo/OAE_0000449

http://purl.obolibrary.org/obo/OAE_0001024

http://purl.obolibrary.org/obo/OAE_0000496

http://purl.obolibrary.org/obo/OAE_0001186

http://purl.obolibrary.org/obo/OAE_0000391

http://purl.obolibrary.org/obo/OAE_0001448

http://purl.obolibrary.org/obo/OAE_0000300

http://purl.obolibrary.org/obo/OAE_0001280

http://purl.obolibrary.org/obo/OAE_0001291

http://purl.obolibrary.org/obo/OAE_0000268

http://purl.obolibrary.org/obo/OAE_0000600

http://purl.obolibrary.org/obo/OAE_0000197

http://purl.obolibrary.org/obo/OAE_0000534

http://purl.obolibrary.org/obo/OAE_0000385

http://purl.obolibrary.org/obo/OAE_0001489

http://purl.obolibrary.org/obo/OAE_0001164

http://purl.obolibrary.org/obo/OAE_0000405

http://purl.obolibrary.org/obo/OAE_0000866

http://purl.obolibrary.org/obo/OAE_0000418

http://purl.obolibrary.org/obo/OAE_0001340

http://purl.obolibrary.org/obo/OAE_0001003

http://purl.obolibrary.org/obo/OAE_0001374

http://purl.obolibrary.org/obo/OAE_0001742

http://purl.obolibrary.org/obo/OAE_0001538

http://purl.obolibrary.org/obo/OAE_0001135

http://purl.obolibrary.org/obo/OAE_0000236

http://purl.obolibrary.org/obo/OAE_0000596

http://purl.obolibrary.org/obo/OAE_0001030

http://purl.obolibrary.org/obo/OAE_0000894

http://purl.obolibrary.org/obo/OAE_0001433

http://purl.obolibrary.org/obo/OAE_0000468

http://purl.obolibrary.org/obo/OAE_0001098

http://purl.obolibrary.org/obo/OAE_0001063

http://purl.obolibrary.org/obo/OAE_0000306

http://purl.obolibrary.org/obo/OAE_0001378

http://purl.obolibrary.org/obo/OAE_0000479

http://purl.obolibrary.org/obo/OAE_0000374

http://purl.obolibrary.org/obo/OAE_0000630

http://purl.obolibrary.org/obo/OAE_0000250

http://purl.obolibrary.org/obo/OAE_0001364

http://purl.obolibrary.org/obo/OAE_0000539

http://purl.obolibrary.org/obo/OAE_0000506

http://purl.obolibrary.org/obo/OAE_0000470

http://purl.obolibrary.org/obo/OAE_0000839

http://purl.obolibrary.org/obo/OAE_0000424

http://purl.obolibrary.org/obo/OAE_0000597

http://purl.obolibrary.org/obo/OAE_0001170

http://purl.obolibrary.org/obo/OAE_0000365

http://purl.obolibrary.org/obo/OAE_0000469

http://purl.obolibrary.org/obo/OAE_0000343

http://purl.obolibrary.org/obo/OAE_0000447

http://purl.obolibrary.org/obo/OAE_0000319

http://purl.obolibrary.org/obo/OAE_0000691

http://purl.obolibrary.org/obo/OAE_0000376

http://purl.obolibrary.org/obo/OAE_0000194

http://purl.obolibrary.org/obo/OAE_0000084

http://purl.obolibrary.org/obo/OAE_0001463

http://purl.obolibrary.org/obo/OAE_0000911

http://purl.obolibrary.org/obo/OAE_0000487

http://purl.obolibrary.org/obo/OAE_0000184

http://purl.obolibrary.org/obo/OAE_0000382

http://purl.obolibrary.org/obo/OAE_0000414

http://purl.obolibrary.org/obo/OAE_0000460

http://purl.obolibrary.org/obo/OAE_0000402

http://purl.obolibrary.org/obo/OAE_0000034

http://purl.obolibrary.org/obo/OAE_0000415

http://purl.obolibrary.org/obo/OAE_0000601

http://purl.obolibrary.org/obo/OAE_0000310

http://purl.obolibrary.org/obo/OAE_0000645

http://purl.obolibrary.org/obo/OAE_0000453

http://purl.obolibrary.org/obo/OAE_0000647

http://purl.obolibrary.org/obo/OAE_0001166

http://purl.obolibrary.org/obo/OAE_0000038

http://purl.obolibrary.org/obo/OAE_0001026

http://purl.obolibrary.org/obo/OAE_0000086

http://purl.obolibrary.org/obo/OAE_0000350

http://purl.obolibrary.org/obo/OAE_0000476

http://purl.obolibrary.org/obo/OAE_0000395

http://purl.obolibrary.org/obo/OAE_0000166

http://purl.obolibrary.org/obo/OAE_0000211

http://purl.obolibrary.org/obo/OAE_0000660

http://purl.obolibrary.org/obo/OAE_0000602

http://purl.obolibrary.org/obo/OAE_0000536

http://purl.obolibrary.org/obo/OAE_0000210

http://purl.obolibrary.org/obo/OAE_0000527

http://purl.obolibrary.org/obo/OAE_0000514

http://purl.obolibrary.org/obo/OAE_0000561

http://purl.obolibrary.org/obo/OAE_0000388

http://purl.obolibrary.org/obo/OAE_0000584

http://purl.obolibrary.org/obo/OAE_0000882

http://purl.obolibrary.org/obo/OAE_0002122

http://purl.obolibrary.org/obo/OAE_0000779

http://purl.obolibrary.org/obo/OAE_0001365

http://purl.obolibrary.org/obo/OAE_0000362

http://purl.obolibrary.org/obo/OAE_0000304

http://purl.obolibrary.org/obo/OAE_0000340

http://purl.obolibrary.org/obo/OAE_0001309

http://purl.obolibrary.org/obo/OAE_0000607

http://purl.obolibrary.org/obo/OAE_0000618

http://purl.obolibrary.org/obo/OAE_0000373

http://purl.obolibrary.org/obo/OAE_0000551

has pharmacological target

http://purl.obolibrary.org/obo/dinto_1581

http://purl.obolibrary.org/obo/dinto_3877

has role

http://purl.obolibrary.org/obo/CHEBI_35569

http://purl.obolibrary.org/obo/CHEBI_51371

InChI

InChI=1S/C9H8ClN5S/c10-5-1-2-6-8(15-16-14-6)7(5)13-9-11-3-4-12-9/h1-2H,3-4H2,(H2,11,12,13)

InChIKey

InChIKey=XFYDIVBRZNQMJC-UHFFFAOYSA-N

is metabolised by

http://purl.obolibrary.org/obo/dinto_2651

label

tizanidine

prefixIRI

obo2:CHEBI_63629

prefLabel

tizanidine

SMILES

ClC1=C(NC2=NCCN2)C2=NSN=C2C=C1

Clc1ccc2nsnc2c1NC1=NCCN1

Synonym

tizanidine

C9H8ClN5S

tizanidina

5-Chloro-4-(2-imidazolin-2-ylamino)-2,1,3-benzothiadiazole

5-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-2,1,3-benzothiadiazol-4-amine

tizanidinum

Tizanidine

xref

PharmGKB:PA451701

CiteXplore:21982341

Reaxys:618691

Drugs Product Database (DPD):2259893

CASRN:51322-75-9

Wikipedia:Tizanidine

KEGG COMPOUND:C07452

Patent:US3843668

CiteXplore:22196407

CiteXplore:21733633

KEGG DRUG:D08611

PubChem Compound:5487

ChEMBL:240117

ChemSpider:5287

CiteXplore:22223284

BindingDB:50240671

Wikipedia:http://en.wikipedia.org/wiki/Tizanidine

Drugs.com:http://www.drugs.com/tizanidine.html

CiteXplore:21317414

DrugBank:DB00697

RxList:http://www.rxlist.com/cgi/generic/tizanidine.htm

National Drug Code Directory:0378-0722-01

CASRN:618691

PubChem Substance:46505373

subClassOf

http://purl.obolibrary.org/obo/dinto_000055

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http://purl.bioontology.org/ontology/LNC/LP61793-3 LOINC LOOM
http://purl.bioontology.org/ontology/UATC/M03BX02 ATC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C023754 RH-MESH LOOM
http://purl.bioontology.org/ontology/RCD/j87.. RCD LOOM
http://www.co-ode.org/ontologies/galen#Tizanidine GALEN LOOM
http://purl.bioontology.org/ontology/MESH/C023754 MESH LOOM
http://stirdf.jst.go.jp/id/200907063886433460 IOBC LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0146011 OCHV LOOM
http://purl.bioontology.org/ontology/VANDF/4021025 VANDF LOOM
http://purl.bioontology.org/ontology/LNC/MTHU025335 LOINC LOOM
http://scai.fraunhofer.de/MSOntology#Tizanidine MSO LOOM
http://purl.jp/bio/4/id/200906044009238909 IOBC LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000148492 ODAE LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61976 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61976 NCIT LOOM
http://purl.bioontology.org/ontology/NDDF/006021 NDDF LOOM
http://www.drugbank.ca/drugs/DB00697 FTC LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/373440006 SNOMEDCT LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#16548 OCHV LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000148492 NDFRT LOOM
http://purl.bioontology.org/ontology/RXNORM/57258 RXNORM LOOM
http://purl.obolibrary.org/obo/CHEBI_63629 ODNAE LOOM
http://purl.obolibrary.org/obo/CHEBI_63629 ODNAE SAME_URI
http://purl.obolibrary.org/obo/CHEBI_63629 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_63629 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_63629 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_63629 DRON SAME_URI
http://purl.obolibrary.org/obo/CHEBI_63629 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_63629 CHEBI SAME_URI