The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Preferred Name

levofloxacin

Synonyms

(-)-Ofloxacin

(S)-Ofloxacin

Ofloxacin S-(-)-form

L-Ofloxacin

(S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid

(S)-(-)-9-fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzooxazine-6-carboxylic acid

(2S)-7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.0^{5,13}]trideca-5(13),6,8,11-tetraene-11-carboxylic acid

levofloxacin

(3S)-(-)-9-fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylic acid

levofloxacino

C18H20FN3O4

levofloxacinum

levofloxacine

(3S)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid

ID

http://purl.obolibrary.org/obo/CHEBI_63598

AHFScode

08:12.18

altId

CHEBI:6440

ATCCode

S01AE05

J01MA12

CASRN

100986-85-4

DBBrand

volequin

tavanic

mosardal

nofaxin

elequine

cravit

cravit ophthalmic

floxel

lesacin

levoxacin

reskuin

levokacin

iquix

levaquin

quixin

leroxacin

levox

DBname

levofloxacin

DBSynonym

l-ofloxacin

Definition

An optically active form of ofloxacin having (S)-configuration; an inhibitor of bacterial topoisomerase IV and DNA gyrase

has pharmacological target

http://purl.obolibrary.org/obo/dinto_0551

http://purl.obolibrary.org/obo/dinto_2751

http://purl.obolibrary.org/obo/dinto_1028

has role

http://purl.obolibrary.org/obo/CHEBI_36047

http://purl.obolibrary.org/obo/CHEBI_53559

http://purl.obolibrary.org/obo/CHEBI_59517

InChI

InChI=1S/C18H20FN3O4/c1-10-9-26-17-14-11(16(23)12(18(24)25)8-22(10)14)7-13(19)15(17)21-5-3-20(2)4-6-21/h7-8,10H,3-6,9H2,1-2H3,(H,24,25)/t10-/m0/s1

InChIKey

InChIKey=GSDSWSVVBLHKDQ-JTQLQIEISA-N

inhibits

http://purl.obolibrary.org/obo/dinto_2814

http://purl.obolibrary.org/obo/dinto_0901

http://purl.obolibrary.org/obo/dinto_1440

http://purl.obolibrary.org/obo/dinto_0551

http://purl.obolibrary.org/obo/dinto_1979

http://purl.obolibrary.org/obo/dinto_2751

http://purl.obolibrary.org/obo/dinto_2651

http://purl.obolibrary.org/obo/dinto_1028

is transported by

http://purl.obolibrary.org/obo/dinto_1440

http://purl.obolibrary.org/obo/dinto_0520

label

levofloxacin

prefixIRI

obo2:CHEBI_63598

prefLabel

levofloxacin

SMILES

C[C@H]1COc2c(N3CCN(C)CC3)c(F)cc3c2n1cc(C(O)=O)c3=O

C[C@H]1COC2=C3N1C=C(C(O)=O)C(=O)C3=CC(F)=C2N1CCN(C)CC1

Synonym

(-)-Ofloxacin

(S)-Ofloxacin

Ofloxacin S-(-)-form

L-Ofloxacin

(S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid

(S)-(-)-9-fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzooxazine-6-carboxylic acid

(2S)-7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.0^{5,13}]trideca-5(13),6,8,11-tetraene-11-carboxylic acid

levofloxacin

(3S)-(-)-9-fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylic acid

levofloxacino

C18H20FN3O4

levofloxacinum

levofloxacine

(3S)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid

xref

PubChem Substance:46505134

Wikipedia:http://en.wikipedia.org/wiki/Levofloxacin

Reaxys:5385660

KEGG COMPOUND:C07660

ChemSpider:131410

Wikipedia:Levofloxacin

CiteXplore:22088660

PubChem Compound:149096

CiteXplore:21974858

KEGG DRUG:D08120

CASRN:100986-85-4

HMDB:HMDB01929

Drugs.com:http://www.drugs.com/cdi/levofloxacin-drops.html

DrugBank:DB01137

ChEMBL:101795

CiteXplore:21965436

National Drug Code Directory:68669-135-05

RxList:http://www.rxlist.com/cgi/generic2/quixin.htm

BindingDB:50167506

PDRhealth:http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/flo1181.shtml

CiteXplore:22221614

PharmGKB:PA450214

CiteXplore:21075586

Drugs Product Database (DPD):2248263

subClassOf

http://purl.obolibrary.org/obo/dinto_000055

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http://purl.bioontology.org/ontology/MESH/D064704 MESH LOOM
http://purl.bioontology.org/ontology/VANDF/4021005 VANDF LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000148474 NDFRT LOOM
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http://purl.bioontology.org/ontology/UATC/J01MA12 ATC LOOM
http://www.drugbank.ca/drugs/DB01137 FTC LOOM
http://purl.bioontology.org/ontology/LNC/MTHU009097 LOINC LOOM
http://purl.bioontology.org/ontology/LNC/LP17276-4 LOINC LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387552007 SNOMEDCT LOOM
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http://purl.jp/bio/4/id/200906067864073585 IOBC LOOM
http://purl.jp/bio/4/id/200906067864073585 IOBC LOOM
http://purl.jp/bio/4/id/200906067864073585 IOBC LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000037941 PDQ LOOM
http://purl.bioontology.org/ontology/RXNORM/82122 RXNORM LOOM
http://stirdf.jst.go.jp/id/200907015113123220 IOBC LOOM
http://stirdf.jst.go.jp/id/200907015113123220 IOBC LOOM
http://stirdf.jst.go.jp/id/200907015113123220 IOBC LOOM
http://stirdf.jst.go.jp/id/200907015113123220 IOBC LOOM
http://purl.obolibrary.org/obo/ARO_0000071 ARO LOOM
http://purl.obolibrary.org/obo/ARO_0000071 ARO LOOM
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http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1586 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1586 NCIT LOOM
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http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1586 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1586 NCIT LOOM
http://www.co-ode.org/ontologies/galen#Levofloxacin GALEN LOOM
http://purl.bioontology.org/ontology/SNMI/C-55791 SNMI LOOM
http://purl.bioontology.org/ontology/RCD/egC.. RCD LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0005582 DDO LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0005582 DMTO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.438.810.835.322.500.500 RH-MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D064704 RH-MESH LOOM
http://purl.obolibrary.org/obo/CHEBI_63598 ODNAE LOOM
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http://purl.obolibrary.org/obo/CHEBI_63598 GENEPIO LOOM
http://purl.obolibrary.org/obo/CHEBI_63598 GENEPIO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_63598 PHIPO LOOM
http://purl.obolibrary.org/obo/CHEBI_63598 PHIPO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_63598 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_63598 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_63598 CHEBI LOOM
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http://purl.obolibrary.org/obo/CHEBI_63598 CHEBI LOOM
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http://purl.obolibrary.org/obo/CHEBI_63598 CHEBI LOOM
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http://purl.obolibrary.org/obo/CHEBI_63598 GENEPIO LOOM
http://purl.obolibrary.org/obo/CHEBI_63598 GENEPIO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_63598 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_63598 DRON SAME_URI
http://purl.obolibrary.org/obo/CHEBI_63598 GENEPIO LOOM
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http://purl.obolibrary.org/obo/CHEBI_63598 CHEBI LOOM
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http://purl.obolibrary.org/obo/DDO.owl#DDO_0005578 DDO LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0005578 DMTO LOOM