The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
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Preferred Name

methysergide
Synonyms

(+)-N-(1-(Hydroxymethyl)propyl)-1-methyl-D-lysergamide

N-(1-(Hydroxymethyl)propyl)-1-methyl-dextro-(+)-lysergamide

9,10-Didehydro-N-(1-(hydroxymethyl)propyl)-1,6-dimethylergoline-8-carboxamide

1-Methyllysergic acid butanolamide

C21H27N3O2

metisergida

(4R,7R)-N-(1-hydroxybutan-2-yl)-6,11-dimethyl-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca-1(16),2,9,12,14-pentaene-4-carboxamide

methysergide

1-Methyl-dextro-lysergic acid (+)-1-hydroxy-2-butylamide

Methysergide

(8R)-N-[1-hydroxymethyl(propyl)]-1,6-dimethyl-9,10-didehydroergoline-8-carboxamide

1-Methylmethylergonovine

methysergidum

1-Methyl-D-lysergic acid butanolamide

(+)-9,10-Didehydro-N-(1-(hydroxymethyl)propyl)-1,6-dimethylergoline-8beta-carboxamide
ID

http://purl.obolibrary.org/obo/CHEBI_584020
activates

http://purl.obolibrary.org/obo/dinto_1166
AHFScode

12:16.00
altId

CHEBI:6893
ATCCode

N02CA04
blocks

http://purl.obolibrary.org/obo/dinto_3340

http://purl.obolibrary.org/obo/dinto_0510

http://purl.obolibrary.org/obo/dinto_0392

http://purl.obolibrary.org/obo/dinto_0648
CASRN

361-37-5
DBBrand

desernil

deseril

deseryl

desernyl

sansert
DBname

methysergide
DBSynonym

methysergidum [inn-latin]

n-(alpha-(hydroxymethyl)propyl)-1-methyl-dextro-lysergamide

methyllysergic acid butanolamide

n-(1-(hydroxymethyl)propyl)-1-methyl-dextro-(+)-lysergamide

methysergid

metisergide [dcit]

metisergido [inn-spanish]
Definition

A synthetic ergot alkaloid, structurally related to the oxytocic agent methylergonovine and to the potent hallucinogen LSD and used prophylactically to reduce the frequency and intensity of severe vascular headaches.
has effect

http://purl.obolibrary.org/obo/OAE_0000388

http://purl.obolibrary.org/obo/OAE_0000879

http://purl.obolibrary.org/obo/OAE_0000589

http://purl.obolibrary.org/obo/OAE_0000902

http://purl.obolibrary.org/obo/OAE_0000406

http://purl.obolibrary.org/obo/OAE_0001449

http://purl.obolibrary.org/obo/OAE_0000415

http://purl.obolibrary.org/obo/OAE_0000021

http://purl.obolibrary.org/obo/OAE_0001448

http://purl.obolibrary.org/obo/OAE_0000600

http://purl.obolibrary.org/obo/OAE_0000310

http://purl.obolibrary.org/obo/OAE_0000920

http://purl.obolibrary.org/obo/OAE_0000601

http://purl.obolibrary.org/obo/OAE_0000375

http://purl.obolibrary.org/obo/OAE_0000551

http://purl.obolibrary.org/obo/OAE_0001515

http://purl.obolibrary.org/obo/OAE_0002206

http://purl.obolibrary.org/obo/OAE_0000542

http://purl.obolibrary.org/obo/OAE_0000414

http://purl.obolibrary.org/obo/OAE_0000355

http://purl.obolibrary.org/obo/OAE_0000034

http://purl.obolibrary.org/obo/OAE_0000385

http://purl.obolibrary.org/obo/OAE_0000602

http://purl.obolibrary.org/obo/OAE_0001217

http://purl.obolibrary.org/obo/OAE_0000390

http://purl.obolibrary.org/obo/OAE_0000362

http://purl.obolibrary.org/obo/OAE_0000374

http://purl.obolibrary.org/obo/OAE_0000402

http://purl.obolibrary.org/obo/OAE_0001298
has pharmacological target

http://purl.obolibrary.org/obo/dinto_3340

http://purl.obolibrary.org/obo/dinto_0510

http://purl.obolibrary.org/obo/dinto_1166

http://purl.obolibrary.org/obo/dinto_0392

http://purl.obolibrary.org/obo/dinto_0648
has role

http://purl.obolibrary.org/obo/CHEBI_66991

http://purl.obolibrary.org/obo/CHEBI_48279

http://purl.obolibrary.org/obo/CHEBI_50514
InChI

InChI=1S/C21H27N3O2/c1-4-15(12-25)22-21(26)14-8-17-16-6-5-7-18-20(16)13(10-23(18)2)9-19(17)24(3)11-14/h5-8,10,14-15,19,25H,4,9,11-12H2,1-3H3,(H,22,26)/t14-,15?,19-/m1/s1
InChIKey

InChIKey=KPJZHOPZRAFDTN-NQUBZZJWSA-N
label

methysergide
may interact with

http://purl.obolibrary.org/obo/CHEBI_8214

http://purl.obolibrary.org/obo/CHEBI_119486

http://purl.obolibrary.org/obo/CHEBI_119573

http://purl.obolibrary.org/obo/CHEBI_3437

http://purl.obolibrary.org/obo/CHEBI_8499

http://purl.obolibrary.org/obo/CHEBI_520985

http://purl.obolibrary.org/obo/CHEBI_4856

http://purl.obolibrary.org/obo/CHEBI_63622

http://purl.obolibrary.org/obo/CHEBI_3127

http://purl.obolibrary.org/obo/dinto_DB00373

http://purl.obolibrary.org/obo/CHEBI_238698

http://purl.obolibrary.org/obo/CHEBI_48273

http://purl.obolibrary.org/obo/CHEBI_10650

http://purl.obolibrary.org/obo/CHEBI_7478

http://purl.obolibrary.org/obo/CHEBI_3441

http://purl.obolibrary.org/obo/CHEBI_2904

http://purl.obolibrary.org/obo/dinto_DB01361

http://purl.obolibrary.org/obo/dinto_DB01359

http://purl.obolibrary.org/obo/CHEBI_28787

http://purl.obolibrary.org/obo/CHEBI_60072

http://purl.obolibrary.org/obo/CHEBI_3732

http://purl.obolibrary.org/obo/CHEBI_6904

http://purl.obolibrary.org/obo/CHEBI_64355

http://purl.obolibrary.org/obo/CHEBI_55344

http://purl.obolibrary.org/obo/CHEBI_2379

http://purl.obolibrary.org/obo/CHEBI_3082

http://purl.obolibrary.org/obo/dinto_DB01105

http://purl.obolibrary.org/obo/dinto_DB01580

http://purl.obolibrary.org/obo/dinto_DB00199

http://purl.obolibrary.org/obo/CHEBI_7444

http://purl.obolibrary.org/obo/CHEBI_6062

http://purl.obolibrary.org/obo/CHEBI_6061

http://purl.obolibrary.org/obo/CHEBI_31739

http://purl.obolibrary.org/obo/CHEBI_10124

http://purl.obolibrary.org/obo/CHEBI_6343

http://purl.obolibrary.org/obo/CHEBI_50922

http://purl.obolibrary.org/obo/dinto_DB00998

http://purl.obolibrary.org/obo/CHEBI_258351

http://purl.obolibrary.org/obo/dinto_DB00976
prefixIRI

obo2:CHEBI_584020
prefLabel

methysergide
SMILES

[H][C@@]12Cc3cn(C)c4cccc(C1=C[C@H](CN2C)C(=O)NC(CC)CO)c34

[H][C@@]12CC3=CN(C)C4=C3C(=CC=C4)C1=C[C@H](CN2C)C(=O)NC(CC)CO
Synonym

(+)-N-(1-(Hydroxymethyl)propyl)-1-methyl-D-lysergamide

N-(1-(Hydroxymethyl)propyl)-1-methyl-dextro-(+)-lysergamide

9,10-Didehydro-N-(1-(hydroxymethyl)propyl)-1,6-dimethylergoline-8-carboxamide

1-Methyllysergic acid butanolamide

C21H27N3O2

metisergida

(4R,7R)-N-(1-hydroxybutan-2-yl)-6,11-dimethyl-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca-1(16),2,9,12,14-pentaene-4-carboxamide

methysergide

1-Methyl-dextro-lysergic acid (+)-1-hydroxy-2-butylamide

Methysergide

(8R)-N-[1-hydroxymethyl(propyl)]-1,6-dimethyl-9,10-didehydroergoline-8-carboxamide

1-Methylmethylergonovine

methysergidum

1-Methyl-D-lysergic acid butanolamide

(+)-9,10-Didehydro-N-(1-(hydroxymethyl)propyl)-1,6-dimethylergoline-8beta-carboxamide
xref

DrugBank:DB00247

RxList:http://www.rxlist.com/cgi/generic3/sansert.htm

Wikipedia:http://en.wikipedia.org/wiki/Methysergide

PharmGKB:PA164743265

BindingDB:50031942

ChEBI:584020

CASRN:361-37-5

National Drug Code Directory:0078-0058-05

Patent:GB854569

Guide To Pharmacology:134

Patent:US3113133

Drugs Product Database (DPD):27499

KEGG DRUG:D02357

IUPHAR:134

Beilstein:765986

KEGG COMPOUND:C07199
subClassOf

http://purl.obolibrary.org/obo/dinto_000055
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http://purl.obolibrary.org/obo/CHEBI_584020 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_584020 PDRO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_584020 BERO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_584020 BIOMODELS SAME_URI
http://purl.obolibrary.org/obo/CHEBI_584020 DRON SAME_URI
http://purl.obolibrary.org/obo/CHEBI_584020 NIFSTD SAME_URI
http://purl.obolibrary.org/obo/CHEBI_584020 CHEBI LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#8068 OCHV LOOM
http://www.gamuts.net/entity#methysergide GAMUTS LOOM
http://purl.bioontology.org/ontology/NDDF/004806 NDDF LOOM
http://purl.obolibrary.org/obo/OMIT_0009840 OMIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C66123 NCIT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.549.439.689 RH-MESH LOOM
https://go.drugbank.com/drugs/DB00247 MDM LOOM
http://purl.obolibrary.org/obo/MESH_D008784 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_584020 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_584020 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_584020 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_584020 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_584020 NIFSTD LOOM
http://purl.bioontology.org/ontology/MESH/D008784 MESH LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0025842 OCHV LOOM
http://purl.bioontology.org/ontology/VANDF/4019833 VANDF LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.132.327.287.689 RH-MESH LOOM
http://purl.obolibrary.org/obo/CHEBI_6893 NIFSTD LOOM
http://www.co-ode.org/ontologies/galen#Methysergide GALEN LOOM
http://purl.bioontology.org/ontology/ATC/N02CA04 ATC LOOM
http://purl.bioontology.org/ontology/SNMI/C-68480 SNMI LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D008784 RH-MESH LOOM
http://purl.bioontology.org/ontology/RCD/x01RA RCD LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147921 NDFRT LOOM
http://purl.bioontology.org/ontology/RXNORM/6911 RXNORM LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387044000 SNOMEDCT LOOM
http://www.drugbank.ca/drugs/DB00247 FTC LOOM
http://www.phoc.org.cn/pmo/class/PMO_00018010 PMAPP-PMO LOOM
http://purl.obolibrary.org/obo/NCIT_C66123 BERO LOOM