loading...| Preferred Name |
hydroxychloroquine |
|
| Synonyms |
hydroxychloroquinum 7-chloro-4-[5-(N-ethyl-N-2-hydroxyethylamino)-2-pentyl]aminoquinoline 7-chloro-4-[4-(N-ethyl-N-beta-hydroxyethylamino)-1-methylbutylamino]quinoline 7-chloro-4-(4-(N-ethyl-N-beta-hydroxyethylamino)-1-methylbutylamino)quinoline hydroxychloroquine 2-[{4-[(7-chloroquinolin-4-yl)amino]pentyl}(ethyl)amino]ethanol oxichlorochine C18H26ClN3O hidroxicloroquina (+-)-hydroxychloroquine 2-({4-[(7-chloroquinolin-4-yl)amino]pentyl}(ethyl)amino)ethan-1-ol Polirreumin 2-(N-(4-(7-chlor-4-chinolylamino)-4-methylbutyl)ethylamino)ethanol 7-chloro-4-(4-(ethyl(2-hydroxyethyl)amino)-1-methylbutylamino)quinoline oxichloroquine NSC4375 2-((4-((7-chloro-4-quinolyl)amino)pentyl)ethylamino)ethanol |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_5801 |
|
| ATCCode |
P01BA02 |
|
| blocks | ||
| CASRN |
118-42-3 |
|
| DBBrand |
quensyl plaquenil axemal dolquine polirreumin ercoquin |
|
| DBname |
hydroxychloroquine |
|
| DBSalt |
hydroxychloroquine sulfate |
|
| DBSynonym |
hcq |
|
| Definition |
An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions. |
|
| has effect |
http://purl.obolibrary.org/obo/OAE_0000238 http://purl.obolibrary.org/obo/OAE_0000388 http://purl.obolibrary.org/obo/OAE_0000785 http://purl.obolibrary.org/obo/OAE_0000573 http://purl.obolibrary.org/obo/OAE_0000377 http://purl.obolibrary.org/obo/OAE_0001510 http://purl.obolibrary.org/obo/OAE_0000376 http://purl.obolibrary.org/obo/OAE_0001509 http://purl.obolibrary.org/obo/OAE_0000415 http://purl.obolibrary.org/obo/OAE_0000373 http://purl.obolibrary.org/obo/OAE_0000577 http://purl.obolibrary.org/obo/OAE_0001448 http://purl.obolibrary.org/obo/OAE_0000600 http://purl.obolibrary.org/obo/OAE_0000539 http://purl.obolibrary.org/obo/OAE_0000770 http://purl.obolibrary.org/obo/OAE_0001026 http://purl.obolibrary.org/obo/OAE_0000287 http://purl.obolibrary.org/obo/OAE_0000601 http://purl.obolibrary.org/obo/OAE_0001463 http://purl.obolibrary.org/obo/OAE_0001105 http://purl.obolibrary.org/obo/OAE_0000268 http://purl.obolibrary.org/obo/OAE_0000086 http://purl.obolibrary.org/obo/OAE_0000510 http://purl.obolibrary.org/obo/OAE_0000645 http://purl.obolibrary.org/obo/OAE_0000584 http://purl.obolibrary.org/obo/OAE_0001129 http://purl.obolibrary.org/obo/OAE_0000542 http://purl.obolibrary.org/obo/OAE_0000607 http://purl.obolibrary.org/obo/OAE_0000525 http://purl.obolibrary.org/obo/OAE_0000606 http://purl.obolibrary.org/obo/OAE_0000460 http://purl.obolibrary.org/obo/OAE_0000866 http://purl.obolibrary.org/obo/OAE_0000306 |
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| has pharmacological target |
http://purl.obolibrary.org/obo/dinto_2873 |
|
| has role |
http://purl.obolibrary.org/obo/CHEBI_50177 |
|
| InChI |
InChI=1S/C18H26ClN3O/c1-3-22(11-12-23)10-4-5-14(2)21-17-8-9-20-18-13-15(19)6-7-16(17)18/h6-9,13-14,23H,3-5,10-12H2,1-2H3,(H,20,21) |
|
| InChIKey |
InChIKey=XXSMGPRMXLTPCZ-UHFFFAOYSA-N |
|
| inhibits | ||
| label |
hydroxychloroquine |
|
| prefixIRI |
obo2:CHEBI_5801 |
|
| prefLabel |
hydroxychloroquine |
|
| related with | ||
| SMILES |
CCN(CCO)CCCC(C)Nc1ccnc2cc(Cl)ccc12 CCN(CCO)CCCC(C)NC1=C2C=CC(Cl)=CC2=NC=C1 |
|
| Synonym |
hydroxychloroquinum 7-chloro-4-[5-(N-ethyl-N-2-hydroxyethylamino)-2-pentyl]aminoquinoline 7-chloro-4-[4-(N-ethyl-N-beta-hydroxyethylamino)-1-methylbutylamino]quinoline 7-chloro-4-(4-(N-ethyl-N-beta-hydroxyethylamino)-1-methylbutylamino)quinoline hydroxychloroquine 2-[{4-[(7-chloroquinolin-4-yl)amino]pentyl}(ethyl)amino]ethanol oxichlorochine C18H26ClN3O hidroxicloroquina (+-)-hydroxychloroquine 2-({4-[(7-chloroquinolin-4-yl)amino]pentyl}(ethyl)amino)ethan-1-ol Polirreumin 2-(N-(4-(7-chlor-4-chinolylamino)-4-methylbutyl)ethylamino)ethanol 7-chloro-4-(4-(ethyl(2-hydroxyethyl)amino)-1-methylbutylamino)quinoline oxichloroquine NSC4375 2-((4-((7-chloro-4-quinolyl)amino)pentyl)ethylamino)ethanol |
|
| xref |
KEGG COMPOUND:C07043 CiteXplore:23778483 RxList:http://www.rxlist.com/cgi/generic/hquine.htm PharmGKB:PA164777036 ChemSpider:3526 National Drug Code Directory:0955-0790-01 HMDB:HMDB15549 Drugs Product Database (DPD):2017709 Reaxys:253894 CiteXplore:23216212 CiteXplore:23902281 ChEMBL:529737 CiteXplore:23887202 CiteXplore:23218706 Wikipedia:http://en.wikipedia.org/wiki/Hydroxychloroquine Wikipedia:Hydroxychloroquine Patent:US2546658 Drugs.com:http://www.drugs.com/cdi/hydroxychloroquine.html DrugBank:DB01611 CASRN:118-42-3 PubChem Substance:46508459 CiteXplore:23581274 CiteXplore:23485647 PubChem Compound:3652 CiteXplore:23481418 KEGG DRUG:D08050 NIST Chemistry WebBook:118-42-3 |
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| subClassOf |