The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Preferred Name

doxycycline

Synonyms

(4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide

(4S,4AR,5S,5AR,6R,12AS)-4-(DIMETHYLAMINO)-3,5,10,12,12A-PENTAHYDROXY-6-METHYL-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2-CARBOXAMIDE

doxiciclina

doxycycline

doxycycline (anhydrous)

5-hydroxy-alpha-6-deoxytetracycline

6alpha-deoxy-5-oxytetracycline

doxycyclinum

Doxycyclin

C22H24N2O8

Jenacyclin

Supracyclin

Vibramycin

Doxycycline

ID

http://purl.obolibrary.org/obo/CHEBI_50845

AHFScode

08:12.24

52:04.04

altId

CHEBI:4713

CHEBI:42135

ATCCode

J01AA02

A01AB22

CASRN

564-25-0

DBBrand

atridox

novo-doxylin

supracyclin

doxychel

alti-doxycycline

vibra-tabs

nu-doxycycline

vibramycin

doxy-caps

apo-doxy

doryx

oracea

periostat

doxy 100

doxylin

doxytec

doxy-lemmon

monodox

doxycin

jenacyclin

doxychel hyclate

DBname

doxycycline

DBSynonym

doxcycline anhydrous

doxytetracycline

doxycycline hyclate

doxycycline monohydrate

Definition

Tetracycline in which the 5beta-hydrogen is replaced by a hydroxy group, while the 6alpha-hydroxy group is replaced by hydrogen. A semi-synthetic tetracycline antibiotic, it is used to inhibit bacterial protein synthesis and treat non-gonococcal urethritis and cervicitis, exacerbations of bronchitis in patients with chronic obstructive pulmonary disease (COPD), and adult periodontitis.

has pharmacological target

http://purl.obolibrary.org/obo/dinto_0908

http://purl.obolibrary.org/obo/dinto_2852

http://purl.obolibrary.org/obo/dinto_2863

has role

http://purl.obolibrary.org/obo/CHEBI_36047

http://purl.obolibrary.org/obo/CHEBI_38068

InChI

InChI=1S/C22H24N2O8/c1-7-8-5-4-6-9(25)11(8)16(26)12-10(7)17(27)14-15(24(2)3)18(28)13(21(23)31)20(30)22(14,32)19(12)29/h4-7,10,14-15,17,25,27-29,32H,1-3H3,(H2,23,31)/t7-,10+,14+,15-,17-,22-/m0/s1

InChIKey

InChIKey=JBIWCJUYHHGXTC-AKNGSSGZSA-N

inhibits

http://purl.obolibrary.org/obo/dinto_0901

http://purl.obolibrary.org/obo/dinto_0908

http://purl.obolibrary.org/obo/dinto_4301

http://purl.obolibrary.org/obo/dinto_0520

http://purl.obolibrary.org/obo/dinto_2852

http://purl.obolibrary.org/obo/dinto_1975

http://purl.obolibrary.org/obo/dinto_2863

label

doxycycline

may interact with

http://purl.obolibrary.org/obo/CHEBI_9073

http://purl.obolibrary.org/obo/dinto_DB01346

http://purl.obolibrary.org/obo/dinto_DB01604

http://purl.obolibrary.org/obo/dinto_DB00237

http://purl.obolibrary.org/obo/CHEBI_10033

http://purl.obolibrary.org/obo/CHEBI_4913

http://purl.obolibrary.org/obo/dinto_DB01164

http://purl.obolibrary.org/obo/dinto_DB01373

http://purl.obolibrary.org/obo/dinto_DB01320

http://purl.obolibrary.org/obo/CHEBI_31444

http://purl.obolibrary.org/obo/CHEBI_161680

http://purl.obolibrary.org/obo/dinto_DB01606

http://purl.obolibrary.org/obo/CHEBI_102166

http://purl.obolibrary.org/obo/dinto_DB00312

http://purl.obolibrary.org/obo/CHEBI_4513

http://purl.obolibrary.org/obo/CHEBI_28077

http://purl.obolibrary.org/obo/dinto_DB01574

http://purl.obolibrary.org/obo/CHEBI_15367

http://purl.obolibrary.org/obo/dinto_DB01341

http://purl.obolibrary.org/obo/dinto_DB00794

http://purl.obolibrary.org/obo/CHEBI_6758

http://purl.obolibrary.org/obo/CHEBI_18208

http://purl.obolibrary.org/obo/dinto_DB00977

http://purl.obolibrary.org/obo/CHEBI_31794

http://purl.obolibrary.org/obo/CHEBI_4511

http://purl.obolibrary.org/obo/CHEBI_2968

http://purl.obolibrary.org/obo/CHEBI_59594

http://purl.obolibrary.org/obo/CHEBI_44185

http://purl.obolibrary.org/obo/CHEBI_6919

http://purl.obolibrary.org/obo/dinto_DB01357

http://purl.obolibrary.org/obo/dinto_DB00893

http://purl.obolibrary.org/obo/dinto_DB01353

http://purl.obolibrary.org/obo/CHEBI_6827

http://purl.obolibrary.org/obo/dinto_DB01355

http://purl.obolibrary.org/obo/CHEBI_3387

http://purl.obolibrary.org/obo/dinto_DB01352

http://purl.obolibrary.org/obo/CHEBI_133809

http://purl.obolibrary.org/obo/CHEBI_102524

http://purl.obolibrary.org/obo/CHEBI_2676

http://purl.obolibrary.org/obo/dinto_DB01354

http://purl.obolibrary.org/obo/dinto_DB00258

http://purl.obolibrary.org/obo/dinto_DB00306

http://purl.obolibrary.org/obo/CHEBI_50173

http://purl.obolibrary.org/obo/CHEBI_8232

http://purl.obolibrary.org/obo/CHEBI_49566

http://purl.obolibrary.org/obo/CHEBI_7809

http://purl.obolibrary.org/obo/CHEBI_51210

http://purl.obolibrary.org/obo/dinto_DB00532

http://purl.obolibrary.org/obo/CHEBI_5683

http://purl.obolibrary.org/obo/dinto_DB01351

http://purl.obolibrary.org/obo/CHEBI_48947

http://purl.obolibrary.org/obo/CHEBI_6067

http://purl.obolibrary.org/obo/CHEBI_50859

http://purl.obolibrary.org/obo/CHEBI_45367

http://purl.obolibrary.org/obo/CHEBI_9622

http://purl.obolibrary.org/obo/dinto_DB01370

http://purl.obolibrary.org/obo/CHEBI_53766

http://purl.obolibrary.org/obo/dinto_DB01593

http://purl.obolibrary.org/obo/CHEBI_2956

http://purl.obolibrary.org/obo/CHEBI_8069

http://purl.obolibrary.org/obo/dinto_DB01592

http://purl.obolibrary.org/obo/CHEBI_5098

http://purl.obolibrary.org/obo/CHEBI_102216

http://purl.obolibrary.org/obo/CHEBI_9398

http://purl.obolibrary.org/obo/CHEBI_28971

http://purl.obolibrary.org/obo/dinto_DB01378

http://purl.obolibrary.org/obo/CHEBI_8107

http://purl.obolibrary.org/obo/CHEBI_3393

http://purl.obolibrary.org/obo/CHEBI_7447

http://purl.obolibrary.org/obo/CHEBI_9587

http://purl.obolibrary.org/obo/CHEBI_4888

http://purl.obolibrary.org/obo/dinto_DB00417

prefixIRI

obo2:CHEBI_50845

prefLabel

doxycycline

SMILES

[H][C@@]12[C@@H](C)C3=C(C(O)=CC=C3)C(=O)C1=C(O)[C@]1(O)C(=O)C(C(N)=O)=C(O)[C@@H](N(C)C)[C@]1([H])[C@H]2O

[H][C@@]12[C@@H](C)c3cccc(O)c3C(=O)C1=C(O)[C@]1(O)C(=O)C(C(N)=O)=C(O)[C@@H](N(C)C)[C@]1([H])[C@H]2O

Synonym

(4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide

(4S,4AR,5S,5AR,6R,12AS)-4-(DIMETHYLAMINO)-3,5,10,12,12A-PENTAHYDROXY-6-METHYL-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2-CARBOXAMIDE

doxiciclina

doxycycline

doxycycline (anhydrous)

5-hydroxy-alpha-6-deoxytetracycline

6alpha-deoxy-5-oxytetracycline

doxycyclinum

Doxycyclin

C22H24N2O8

Jenacyclin

Supracyclin

Vibramycin

Doxycycline

xref

ChEMBL:471546

Patent:US3200149

PubChem Compound:5281011

KEGG COMPOUND:C06973

ChEBI:50845

CASRN:564-25-0

Wikipedia:http://en.wikipedia.org/wiki/Doxycycline

Beilstein:3041790

PDBeChem:DXT

RxList:http://www.rxlist.com/cgi/generic/doxycyc.htm

Drugs.com:http://www.drugs.com/doxycycline.html

ChemSpider:4444486

CiteXplore:1650428

KEGG DRUG:D07876

National Drug Code Directory:49884-091-01

DrugBank:DB00254

Drugs Product Database (DPD):742562

Patent:US3019260

Reaxys:3041790

BindingDB:50041429

PubChem Substance:46506491

Wikipedia:Doxycycline

PharmGKB:PA449415

subClassOf

http://purl.obolibrary.org/obo/dinto_000055

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http://purl.bioontology.org/ontology/RXNORM/3640 RXNORM LOOM
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