The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Preferred Name

mifepristone

Synonyms

Mifeprex

Mifepristone

11beta-[4-(dimethylamino)phenyl]-17beta-hydroxy-17alpha-(prop-1-yn-1-yl)estra-4,9-dien-3-one

Mifegyne

C29H35NO2

(10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]-14-hydroxy-15-methyl-14-(prop-1-yn-1-yl)tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-1,6-dien-5-one

11-(4-DIMETHYLAMINO-PHENYL)-17-HYDROXY-13-METHYL-17-PROP-1-YNYL-1,2,6,7,8,11,12,13,14,15,16,17-DODEC AHYDRO-CYCLOPENTA[A]PHENANTHREN-3-ONE

mifepristona

RU486

mifepristonum

mifepristone

RU-486

ID

http://purl.obolibrary.org/obo/CHEBI_50692

altId

CHEBI:6934

CHEBI:40057

ATCCode

G03XB01

blocks

http://purl.obolibrary.org/obo/dinto_2874

http://purl.obolibrary.org/obo/dinto_3882

CASRN

84371-65-3

DBBrand

corlux

mifeprex

mifegyne

korlym

DBname

mifepristone

DBSynonym

mifepriston

ru486

Definition

A 3-oxo steroid that has formula C29H35NO2.

has effect

http://purl.obolibrary.org/obo/OAE_0000388

http://purl.obolibrary.org/obo/OAE_0000453

http://purl.obolibrary.org/obo/OAE_0000377

http://purl.obolibrary.org/obo/OAE_0000376

http://purl.obolibrary.org/obo/OAE_0001186

http://purl.obolibrary.org/obo/OAE_0000567

http://purl.obolibrary.org/obo/OAE_0000373

http://purl.obolibrary.org/obo/OAE_0000382

http://purl.obolibrary.org/obo/OAE_0000600

http://purl.obolibrary.org/obo/OAE_0000310

http://purl.obolibrary.org/obo/OAE_0000601

http://purl.obolibrary.org/obo/OAE_0000300

http://purl.obolibrary.org/obo/OAE_0000551

http://purl.obolibrary.org/obo/OAE_0000400

http://purl.obolibrary.org/obo/OAE_0000584

http://purl.obolibrary.org/obo/OAE_0002206

http://purl.obolibrary.org/obo/OAE_0000414

http://purl.obolibrary.org/obo/OAE_0000355

http://purl.obolibrary.org/obo/OAE_0000034

http://purl.obolibrary.org/obo/OAE_0000362

http://purl.obolibrary.org/obo/OAE_0000374

http://purl.obolibrary.org/obo/OAE_0000394

http://purl.obolibrary.org/obo/OAE_0000466

http://purl.obolibrary.org/obo/OAE_0001170

http://purl.obolibrary.org/obo/OAE_0001497

http://purl.obolibrary.org/obo/OAE_0000402

has pharmacological target

http://purl.obolibrary.org/obo/dinto_2874

http://purl.obolibrary.org/obo/dinto_3882

has role

http://purl.obolibrary.org/obo/CHEBI_49020

http://purl.obolibrary.org/obo/CHEBI_49323

http://purl.obolibrary.org/obo/CHEBI_49326

http://purl.obolibrary.org/obo/CHEBI_50691

InChI

InChI=1S/C29H35NO2/c1-5-15-29(32)16-14-26-24-12-8-20-17-22(31)11-13-23(20)27(24)25(18-28(26,29)2)19-6-9-21(10-7-19)30(3)4/h6-7,9-10,17,24-26,32H,8,11-14,16,18H2,1-4H3/t24-,25+,26-,28-,29-/m0/s1

InChIKey

InChIKey=VKHAHZOOUSRJNA-GCNJZUOMSA-N

induces

http://purl.obolibrary.org/obo/dinto_0901

http://purl.obolibrary.org/obo/dinto_1440

inhibits

http://purl.obolibrary.org/obo/dinto_2990

http://purl.obolibrary.org/obo/dinto_2993

http://purl.obolibrary.org/obo/dinto_0901

http://purl.obolibrary.org/obo/dinto_1440

http://purl.obolibrary.org/obo/dinto_2828

http://purl.obolibrary.org/obo/dinto_1956

is metabolised by

http://purl.obolibrary.org/obo/dinto_2990

http://purl.obolibrary.org/obo/dinto_0901

label

mifepristone

may interact with

http://purl.obolibrary.org/obo/CHEBI_70746

http://purl.obolibrary.org/obo/CHEBI_72312

http://purl.obolibrary.org/obo/dinto_DB06699

prefixIRI

obo2:CHEBI_50692

prefLabel

mifepristone

SMILES

[H][C@@]12CC[C@@](O)(C#CC)[C@@]1(C)C[C@H](C1=CC=C(C=C1)N(C)C)C1=C3CCC(=O)C=C3CC[C@@]21[H]

[H][C@@]12CCC3=CC(=O)CCC3=C1[C@H](C[C@@]1(C)[C@@]2([H])CC[C@@]1(O)C#CC)c1ccc(cc1)N(C)C

Synonym

Mifeprex

Mifepristone

11beta-[4-(dimethylamino)phenyl]-17beta-hydroxy-17alpha-(prop-1-yn-1-yl)estra-4,9-dien-3-one

Mifegyne

C29H35NO2

(10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]-14-hydroxy-15-methyl-14-(prop-1-yn-1-yl)tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-1,6-dien-5-one

11-(4-DIMETHYLAMINO-PHENYL)-17-HYDROXY-13-METHYL-17-PROP-1-YNYL-1,2,6,7,8,11,12,13,14,15,16,17-DODEC AHYDRO-CYCLOPENTA[A]PHENANTHREN-3-ONE

mifepristona

RU486

mifepristonum

mifepristone

RU-486

xref

PDBeChem:486

IUPHAR:2805

Drugs.com:http://www.drugs.com/cdi/mifepristone.html

CASRN:84371-65-3

PDB:486

ChemSpider:49889

KEGG COMPOUND:C07652

BindingDB:18627

KEGG DRUG:D00585

RxList:http://www.rxlist.com/cgi/generic3/mifeprist.htm

Wikipedia:http://en.wikipedia.org/wiki/Mifepristone

PubChem Substance:46505795

DrugBank:DB00834

Patent:US4386085

Patent:EP57115

ChEBI:50692

PubChem Compound:55245

ChEMBL:812273

PharmGKB:PA450500

Guide To Pharmacology:2805

subClassOf

http://purl.obolibrary.org/obo/dinto_000055

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Delete Mapping To Ontology Source
http://purl.obolibrary.org/obo/CHEBI_50692 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_50692 PDRO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_50692 FIDEO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_50692 BERO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_50692 BIOMODELS SAME_URI
http://purl.obolibrary.org/obo/CHEBI_50692 DRON SAME_URI
http://purl.obolibrary.org/obo/CHEBI_50692 NIFSTD SAME_URI
http://purl.obolibrary.org/obo/XCO_0000880 XCO LOOM
http://purl.obolibrary.org/obo/CHEBI_50692 CHEBI LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/395796009 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000040888 PDQ LOOM
http://www.drugbank.ca/drugs/DB00834 FTC LOOM
http://purl.obolibrary.org/obo/MESH_D015735 BERO LOOM
https://go.drugbank.com/drugs/DB00834 MDM LOOM
http://purl.obolibrary.org/obo/CHEBI_50692 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_50692 FIDEO LOOM
http://purl.obolibrary.org/obo/CHEBI_50692 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_50692 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_50692 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_50692 NIFSTD LOOM
http://www.co-ode.org/ontologies/galen#Mifepristone GALEN LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#8133 OCHV LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0026088 OCHV LOOM
http://purl.bioontology.org/ontology/RXNORM/6964 RXNORM LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D015735 RH-MESH LOOM
http://purl.bioontology.org/ontology/CSP/4001-0083 CRISP LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D04.808.365.415.580 RH-MESH LOOM
http://purl.obolibrary.org/obo/NCIT_C655 BERO LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000148679 NDFRT LOOM
http://purl.bioontology.org/ontology/VANDF/4021235 VANDF LOOM
http://purl.jp/bio/4/id/200906037182480980 IOBC LOOM
http://purl.bioontology.org/ontology/NDDF/004008 NDDF LOOM
http://purl.bioontology.org/ontology/MESH/D015735 MESH LOOM
http://purl.obolibrary.org/obo/OMIT_0016386 OMIT LOOM
http://www.phoc.org.cn/pmo/class/PMO_00018633 PMAPP-PMO LOOM
http://purl.bioontology.org/ontology/ATC/G03XB01 ATC LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C655 NCIT LOOM
http://stirdf.jst.go.jp/id/200907076006242126 IOBC LOOM