The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Preferred Name

cefepime

Synonyms

(6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-[(1-methylpyrrolidinium-1-yl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

C19H24N6O5S2

7beta-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-3-[(1-methylpyrrolidinium-1-yl)methyl]-3,4-didehydrocepham-4-carboxylate

cefepimum

cefepima

Cefepime

1-{[(6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-2-carboxylato-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl}-1-methylpyrrolidin-1-ium

cefepime

ID

http://purl.obolibrary.org/obo/CHEBI_478164

AHFScode

08:12.06.16

altId

CHEBI:3486

CHEBI:473919

ATCCode

J01DE01

CASRN

88040-23-7

DBBrand

maxcef

maxipime

cepimax

axepim

cepimex

DBname

cefepime

DBSynonym

cefepimum [latin]

cefepima [spanish]

Definition

A cephalosporin bearing (1-methylpyrrolidinium-1-yl)methyl and (2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido groups at positions 3 and 7, respectively, of the cephem skeleton.

has effect

http://purl.obolibrary.org/obo/OAE_0000494

http://purl.obolibrary.org/obo/OAE_0000377

http://purl.obolibrary.org/obo/OAE_0001333

http://purl.obolibrary.org/obo/OAE_0001129

http://purl.obolibrary.org/obo/OAE_0000449

http://purl.obolibrary.org/obo/OAE_0000920

http://purl.obolibrary.org/obo/OAE_0001448

http://purl.obolibrary.org/obo/OAE_0000268

http://purl.obolibrary.org/obo/OAE_0000600

http://purl.obolibrary.org/obo/OAE_0000557

http://purl.obolibrary.org/obo/OAE_0001707

http://purl.obolibrary.org/obo/OAE_0000491

http://purl.obolibrary.org/obo/OAE_0000811

http://purl.obolibrary.org/obo/OAE_0000512

http://purl.obolibrary.org/obo/OAE_0000287

http://purl.obolibrary.org/obo/OAE_0000374

http://purl.obolibrary.org/obo/OAE_0001364

http://purl.obolibrary.org/obo/OAE_0000943

http://purl.obolibrary.org/obo/OAE_0000308

http://purl.obolibrary.org/obo/OAE_0001275

http://purl.obolibrary.org/obo/OAE_0000376

http://purl.obolibrary.org/obo/OAE_0000194

http://purl.obolibrary.org/obo/OAE_0001463

http://purl.obolibrary.org/obo/OAE_0000402

http://purl.obolibrary.org/obo/OAE_0000601

http://purl.obolibrary.org/obo/OAE_0000310

http://purl.obolibrary.org/obo/OAE_0000645

http://purl.obolibrary.org/obo/OAE_0001243

http://purl.obolibrary.org/obo/OAE_0001026

http://purl.obolibrary.org/obo/OAE_0000394

http://purl.obolibrary.org/obo/OAE_0000395

http://purl.obolibrary.org/obo/OAE_0000602

http://purl.obolibrary.org/obo/OAE_0001055

http://purl.obolibrary.org/obo/OAE_0000825

http://purl.obolibrary.org/obo/OAE_0000388

http://purl.obolibrary.org/obo/OAE_0000584

http://purl.obolibrary.org/obo/OAE_0000362

http://purl.obolibrary.org/obo/OAE_0001366

http://purl.obolibrary.org/obo/OAE_0000373

has pharmacological target

http://purl.obolibrary.org/obo/dinto_2967

http://purl.obolibrary.org/obo/dinto_2968

http://purl.obolibrary.org/obo/dinto_0360

http://purl.obolibrary.org/obo/dinto_3095

has role

http://purl.obolibrary.org/obo/CHEBI_36047

InChI

InChI=1S/C19H24N6O5S2/c1-25(5-3-4-6-25)7-10-8-31-17-13(16(27)24(17)14(10)18(28)29)22-15(26)12(23-30-2)11-9-32-19(20)21-11/h9,13,17H,3-8H2,1-2H3,(H3-,20,21,22,26,28,29)/b23-12-/t13-,17-/m1/s1

InChIKey

InChIKey=HVFLCNVBZFFHBT-ZKDACBOMSA-N

inhibits

http://purl.obolibrary.org/obo/dinto_2967

http://purl.obolibrary.org/obo/dinto_2789

http://purl.obolibrary.org/obo/dinto_2004

http://purl.obolibrary.org/obo/dinto_4065

http://purl.obolibrary.org/obo/dinto_2968

http://purl.obolibrary.org/obo/dinto_0360

http://purl.obolibrary.org/obo/dinto_3095

label

cefepime

may interact with

http://purl.obolibrary.org/obo/CHEBI_8426

prefixIRI

obo2:CHEBI_478164

prefLabel

cefepime

SMILES

CON=C(/C(=O)N[C@@H]1C(=O)N2[C@]1([H])SCC(C[N+]1(C)CCCC1)=C2C([O-])=O)C1=CSC(N)=N1

[H][C@]12SCC(C[N+]3(C)CCCC3)=C(N1C(=O)[C@H]2NC(=O)C(=N/OC)\c1csc(N)n1)C([O-])=O

Synonym

(6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-[(1-methylpyrrolidinium-1-yl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

C19H24N6O5S2

7beta-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-3-[(1-methylpyrrolidinium-1-yl)methyl]-3,4-didehydrocepham-4-carboxylate

cefepimum

cefepima

Cefepime

1-{[(6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-2-carboxylato-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl}-1-methylpyrrolidin-1-ium

cefepime

xref

CiteXplore:14628573

CiteXplore:15978309

CiteXplore:15830071

CiteXplore:11864944

CiteXplore:11303846

CiteXplore:11260566

CiteXplore:18651542

CiteXplore:15494381

CiteXplore:15980347

Wikipedia:http://en.wikipedia.org/wiki/Cefepime

Drugs Product Database (DPD):2163632

PubChem Compound:5479537

CiteXplore:11431192

National Drug Code Directory:0338-1301-41

Wikipedia:Cefepime

CiteXplore:12848746

PubChem Substance:46507919

RxList:http://www.rxlist.com/cgi/generic/cefep.htm

CiteXplore:17448937

CiteXplore:21425867

Patent:DE3307550

CiteXplore:18025111

CiteXplore:11442796

CiteXplore:18673128

CASRN:88040-23-7

Patent:US4406899

CiteXplore:15303411

CiteXplore:17323865

CiteXplore:11084674

Beilstein:7453587

CiteXplore:14642333

ChemSpider:4586395

DrugBank:DB01413

CiteXplore:11964152

CiteXplore:11910959

CiteXplore:18154532

CiteXplore:11179650

CiteXplore:11280610

KEGG DRUG:D02376

CiteXplore:11306793

ChEBI:478164

CiteXplore:16650951

Reaxys:7453587

CiteXplore:17214092

CiteXplore:11191931

CiteXplore:17625777

CiteXplore:11328792

CiteXplore:19304881

PharmGKB:PA164754876

CiteXplore:16207962

CiteXplore:16705389

CiteXplore:17042189

CiteXplore:16930923

CiteXplore:19053894

Drugs.com:http://www.drugs.com/cdi/cefepime.html

CiteXplore:18717040

KEGG COMPOUND:C08111

subClassOf

http://purl.obolibrary.org/obo/dinto_000055

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