| Synonyms |
Clomipramine
(3-{5-chloro-2-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-yl}propyl)dimethylamine
chlorimipramine
3-chloroimipramine
3-(3-CHLORO-5H-DIBENZO[B,F]AZEPIN-5-YL)-N,N-DIMETHYLPROPAN-1-AMINE
C19H23ClN2
3-(3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethyl-1-propanamine
monochlorimipramine
3-(3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethylpropan-1-amine
G 34586
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| Definition |
A dibenzoazepine that is 10,11-dihydro-5H-dibenzo[b,f]azepine which is substituted by chlorine at position 3 and in which the hydrogen attached to the nitrogen is replaced by a 3-(dimethylamino)propyl group. One of the more sedating tricyclic antidepressants, it is used as the hydrochloride salt for the treatment of depression as well as obsessive-compulsive disorder and phobias.
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| InChI |
InChI=1S/C19H23ClN2/c1-21(2)12-5-13-22-18-7-4-3-6-15(18)8-9-16-10-11-17(20)14-19(16)22/h3-4,6-7,10-11,14H,5,8-9,12-13H2,1-2H3
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| Synonym |
Clomipramine (3-{5-chloro-2-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-yl}propyl)dimethylamine chlorimipramine 3-chloroimipramine 3-(3-CHLORO-5H-DIBENZO[B,F]AZEPIN-5-YL)-N,N-DIMETHYLPROPAN-1-AMINE C19H23ClN2 3-(3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethyl-1-propanamine monochlorimipramine 3-(3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethylpropan-1-amine G 34586
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| xref |
CiteXplore:12007764 ChEBI:47780 PharmGKB:PA449048 ChemSpider:2699 Wikipedia:Clomipramine KEGG COMPOUND:C06918 CiteXplore:12084414 CASRN:303-49-1 RxList:http://www.rxlist.com/cgi/generic/clomipr.htm IUPHAR:2398 NIST Chemistry WebBook:303-49-1 Patent:US3467650 CiteXplore:16085036 ChEMBL:100996 DrugBank:DB01242 National Drug Code Directory:0781-2027-31 Wikipedia:http://en.wikipedia.org/wiki/Clomipramine PDBeChem:CXX PubChem Compound:2801 CiteXplore:17471183 Reaxys:1323477 CiteXplore:19810911 Drugs.com:http://www.drugs.com/cdi/clomipramine.html CASRN:1323477 PubChem Substance:46505157 Patent:CH371799 Drugs Product Database (DPD):2244818 PDRhealth:http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/ana1020.shtml PDB:CXX Guide To Pharmacology:2398 BindingDB:50021927
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