The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Preferred Name

cefixime

Synonyms

7beta-{(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(carboxymethoxy)imino]acetamido}-3-ethenyl-3,4-didehydrocepham-4-carboxylic acid

C16H15N5O7S2

(-)-cefixim

cefiximum

(6R,7R)-7-({(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(carboxymethoxy)imino]acetyl}amino)-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

cefixime

cefixima

(6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(carboxymethoxy)imino]acetamido]-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

ID

http://purl.obolibrary.org/obo/CHEBI_472657

AHFScode

08:12.06.12

altId

CHEBI:3487

ATCCode

J01DD08

CASRN

79350-37-1

DBBrand

suprax

cephoral

unixime

cefixoral

cfix

oroken

cefspan

DBname

cefixime

DBSynonym

cefiximum [latin]

cefixima [spanish]

cefixim

cefixime anhydrous

Definition

A third-generation cephalosporin antibiotic bearing vinyl and (2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(carboxymethoxy)imino]acetamido groups at positions 3 and 7, respectively, of the cephem skeleton. It is used in the treatment of gonorrhoea, tonsilitis, pharyngitis, bronchitis, and urinary tract infections.

has effect

http://purl.obolibrary.org/obo/OAE_0000377

http://purl.obolibrary.org/obo/OAE_0001333

http://purl.obolibrary.org/obo/OAE_0001129

http://purl.obolibrary.org/obo/OAE_0000449

http://purl.obolibrary.org/obo/OAE_0000920

http://purl.obolibrary.org/obo/OAE_0001448

http://purl.obolibrary.org/obo/OAE_0000268

http://purl.obolibrary.org/obo/OAE_0000600

http://purl.obolibrary.org/obo/OAE_0000468

http://purl.obolibrary.org/obo/OAE_0000811

http://purl.obolibrary.org/obo/OAE_0000287

http://purl.obolibrary.org/obo/OAE_0000374

http://purl.obolibrary.org/obo/OAE_0001364

http://purl.obolibrary.org/obo/OAE_0001434

http://purl.obolibrary.org/obo/OAE_0001275

http://purl.obolibrary.org/obo/OAE_0000376

http://purl.obolibrary.org/obo/OAE_0001217

http://purl.obolibrary.org/obo/OAE_0001463

http://purl.obolibrary.org/obo/OAE_0000402

http://purl.obolibrary.org/obo/OAE_0000601

http://purl.obolibrary.org/obo/OAE_0000645

http://purl.obolibrary.org/obo/OAE_0000453

http://purl.obolibrary.org/obo/OAE_0000454

http://purl.obolibrary.org/obo/OAE_0000536

http://purl.obolibrary.org/obo/OAE_0000210

http://purl.obolibrary.org/obo/OAE_0000825

http://purl.obolibrary.org/obo/OAE_0000388

http://purl.obolibrary.org/obo/OAE_0000584

http://purl.obolibrary.org/obo/OAE_0001365

http://purl.obolibrary.org/obo/OAE_0000362

http://purl.obolibrary.org/obo/OAE_0001366

http://purl.obolibrary.org/obo/OAE_0000373

has pharmacological target

http://purl.obolibrary.org/obo/dinto_2779

has role

http://purl.obolibrary.org/obo/CHEBI_36047

InChI

InChI=1S/C16H15N5O7S2/c1-2-6-4-29-14-10(13(25)21(14)11(6)15(26)27)19-12(24)9(20-28-3-8(22)23)7-5-30-16(17)18-7/h2,5,10,14H,1,3-4H2,(H2,17,18)(H,19,24)(H,22,23)(H,26,27)/b20-9-/t10-,14-/m1/s1

InChIKey

InChIKey=OKBVVJOGVLARMR-QSWIMTSFSA-N

inhibits

http://purl.obolibrary.org/obo/dinto_2789

http://purl.obolibrary.org/obo/dinto_2004

http://purl.obolibrary.org/obo/dinto_2779

http://purl.obolibrary.org/obo/dinto_4065

is transported by

http://purl.obolibrary.org/obo/dinto_2004

label

cefixime

may interact with

http://purl.obolibrary.org/obo/CHEBI_8426

prefixIRI

obo2:CHEBI_472657

prefLabel

cefixime

SMILES

[H][C@]12SCC(C=C)=C(N1C(=O)[C@H]2NC(=O)C(=N/OCC(O)=O)\c1csc(N)n1)C(O)=O

[H][C@]12SCC(C=C)=C(N1C(=O)[C@H]2NC(=O)C(=N/OCC(O)=O)C1=CSC(N)=N1)C(O)=O

Synonym

7beta-{(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(carboxymethoxy)imino]acetamido}-3-ethenyl-3,4-didehydrocepham-4-carboxylic acid

C16H15N5O7S2

(-)-cefixim

cefiximum

(6R,7R)-7-({(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(carboxymethoxy)imino]acetyl}amino)-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

cefixime

cefixima

(6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(carboxymethoxy)imino]acetamido]-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

xref

CASRN:79350-37-1

Wikipedia:http://en.wikipedia.org/wiki/Cefixime

PharmGKB:PA164768821

PDRhealth:http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/sup1416.shtml

Beilstein:6025058

Patent:US4409214

Drugs Product Database (DPD):2195992

KEGG COMPOUND:C06881

KEGG DRUG:D00258

ChEMBL:17116681

Patent:EP30630

DrugBank:DB00671

Drugs.com:http://www.drugs.com/cdi/cefixime.html

ChEBI:472657

RxList:http://www.rxlist.com/cgi/generic/cefixime.htm

subClassOf

http://purl.obolibrary.org/obo/dinto_000055

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http://www.co-ode.org/ontologies/galen#Cefixime GALEN LOOM
http://purl.bioontology.org/ontology/NDDF/002737 NDDF LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D020682 RH-MESH LOOM
http://purl.bioontology.org/ontology/UATC/J01DD08 ATC LOOM
http://purl.bioontology.org/ontology/LNC/LP17701-1 LOINC LOOM
http://purl.jp/bio/4/id/200906065371368125 IOBC LOOM
http://purl.jp/bio/4/id/200906065371368125 IOBC LOOM
http://purl.jp/bio/4/id/200906065371368125 IOBC LOOM
http://purl.jp/bio/4/id/200906065371368125 IOBC LOOM
http://purl.obolibrary.org/obo/DRON_00017900 DRON LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1100 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1100 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1100 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1100 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1100 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1100 NCIT LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147544 NDFRT LOOM
http://stirdf.jst.go.jp/id/200907019822783727 IOBC LOOM
http://stirdf.jst.go.jp/id/200907019822783727 IOBC LOOM
http://stirdf.jst.go.jp/id/200907019822783727 IOBC LOOM
http://stirdf.jst.go.jp/id/200907019822783727 IOBC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.886.665.074.190.190.115 RH-MESH LOOM
http://purl.bioontology.org/ontology/MESH/D020682 MESH LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000037809 PDQ LOOM
http://purl.bioontology.org/ontology/RXNORM/25033 RXNORM LOOM
http://purl.bioontology.org/ontology/LNC/MTHU005580 LOINC LOOM
http://purl.obolibrary.org/obo/ARO_3000646 ARO LOOM
http://purl.obolibrary.org/obo/ARO_3000646 ARO LOOM
http://purl.bioontology.org/ontology/SNMI/C-535C0 SNMI LOOM
http://purl.bioontology.org/ontology/VANDF/4019391 VANDF LOOM
http://purl.bioontology.org/ontology/RCD/e6h.. RCD LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D04.075.080.875.099.221.249.190.190.115 RH-MESH LOOM
http://purl.obolibrary.org/obo/CHEBI_472657 GENEPIO LOOM
http://purl.obolibrary.org/obo/CHEBI_472657 GENEPIO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_472657 PHIPO LOOM
http://purl.obolibrary.org/obo/CHEBI_472657 PHIPO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_472657 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_472657 BIOMODELS SAME_URI
http://purl.obolibrary.org/obo/CHEBI_472657 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_472657 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_472657 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_472657 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_472657 GENEPIO LOOM
http://purl.obolibrary.org/obo/CHEBI_472657 GENEPIO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_472657 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_472657 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_472657 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_472657 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_472657 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_472657 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_472657 GENEPIO LOOM
http://purl.obolibrary.org/obo/CHEBI_472657 GENEPIO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_472657 GENEPIO LOOM
http://purl.obolibrary.org/obo/CHEBI_472657 GENEPIO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_472657 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_472657 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_472657 NIFSTD LOOM
http://purl.obolibrary.org/obo/CHEBI_472657 NIFSTD SAME_URI
http://purl.bioontology.org/ontology/SNOMEDCT/387536009 SNOMEDCT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.065.589.099.249.190.190.115 RH-MESH LOOM