Preferred Name |
ciclopirox |
|
Synonyms |
C12H17NO2 6-cyclohexyl-1-hydroxy-4-methyl-1,2-dihydropyridin-2-one ciclopirox ciclopiroxum 6-cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridinone 6-cyclohexyl-1-hydroxy-4-methylpyridin-2(1H)-one |
|
ID |
http://purl.obolibrary.org/obo/CHEBI_453011 |
|
AHFScode |
84:04.08.20 |
|
ATCCode |
D01AE14 G01AX12 |
|
CASRN |
29342-05-0 |
|
chelates | ||
DBBrand |
stieprox penlac nail lacquer penlac loprox shampoo loprox |
|
DBname |
ciclopirox |
|
DBSynonym |
ciclopiroxum [inn-latin] ciclopirox-olamin ciclopirox olamin hoe 296b ciclopiroxolamine hoe-296b |
|
Definition |
1-Hydroxypyridin-2(1H)-one in which the hydrogens at positions 4 and 6 are substituted by methyl and cyclohexyl groups, repectively. A broad spectrum antigfungal agent, it also exhibits antibacterial activity against many Gram-positive and Gram-negative bacteria, and has anti-inflammatory properties. It is used a a topical treatment of fungal skin and nail infections. |
|
has effect |
http://purl.obolibrary.org/obo/OAE_0000377 http://purl.obolibrary.org/obo/OAE_0000443 http://purl.obolibrary.org/obo/OAE_0000415 http://purl.obolibrary.org/obo/OAE_0000373 http://purl.obolibrary.org/obo/OAE_0000250 http://purl.obolibrary.org/obo/OAE_0000645 http://purl.obolibrary.org/obo/OAE_0000894 http://purl.obolibrary.org/obo/OAE_0000355 http://purl.obolibrary.org/obo/OAE_0000362 |
|
has pharmacological target | ||
has role |
http://purl.obolibrary.org/obo/CHEBI_59010 |
|
InChI |
InChI=1S/C12H17NO2/c1-9-7-11(13(15)12(14)8-9)10-5-3-2-4-6-10/h7-8,10,15H,2-6H2,1H3 |
|
InChIKey |
InChIKey=SCKYRAXSEDYPSA-UHFFFAOYSA-N |
|
label |
ciclopirox |
|
prefixIRI |
obo2:CHEBI_453011 |
|
prefLabel |
ciclopirox |
|
SMILES |
CC1=CC(=O)N(O)C(=C1)C1CCCCC1 Cc1cc(C2CCCCC2)n(O)c(=O)c1 |
|
Synonym |
C12H17NO2 6-cyclohexyl-1-hydroxy-4-methyl-1,2-dihydropyridin-2-one ciclopirox ciclopiroxum 6-cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridinone 6-cyclohexyl-1-hydroxy-4-methylpyridin-2(1H)-one |
|
xref |
Drugs.com:http://www.drugs.com/cdi/ciclopirox-cream.html DrugBank:DB01188 ChEMBL:17253868 National Drug Code Directory:0066-8008-01 CASRN:29342-05-0 ChemSpider:2647 Drugs Product Database (DPD):2247228 PubChem Substance:46506333 PharmGKB:PA164747060 Beilstein:1533423 PDRhealth:http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/lop1236.shtml BindingDB:50231223 PubChem Compound:2749 RxList:http://www.rxlist.com/cgi/generic3/penlac.htm Wikipedia:Ciclopirox Patent:US3883545 Wikipedia:http://en.wikipedia.org/wiki/Ciclopirox ChEMBL:16854048 KEGG DRUG:D03488 |
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subClassOf |